Product References
Tryptophanemia is controlled by a tryptophan-sensing mechanism ubiquitinating tryptophan 2,3-dioxygenase.
Proceedings of the National Academy of Sciences of the United States of America
Klaessens S,Stroobant V,Hoffmann D,Gyrd-Hansen M,Pilotte L,Vigneron N,De Plaen E,Van den Eynde BJ
MA1-24750 was used in Western Blot to show that tryptophan homeostasis is largely controlled by the stability of tryptophan 2,3-dioxygenase (TDO), the hepatic enzyme responsible for tryptophan catabolism.
Tue Jun 08 00:00:00 UTC 2021
Tryptophanemia is controlled by a tryptophan-sensing mechanism ubiquitinating tryptophan 2,3-dioxygenase.
Proceedings of the National Academy of Sciences of the United States of America
Klaessens S,Stroobant V,Hoffmann D,Gyrd-Hansen M,Pilotte L,Vigneron N,De Plaen E,Van den Eynde BJ
MA1-24750 was used in Western Blot to show that tryptophan homeostasis is largely controlled by the stability of tryptophan 2,3-dioxygenase (TDO), the hepatic enzyme responsible for tryptophan catabolism.
Tue Jun 08 00:00:00 UTC 2021
Stathmin 1 Induces Murine Hepatocyte Proliferation and Increased Liver Mass.
Hepatology communications
Zhao E,Shen Y,Amir M,Farris AB,Czaja MJ
MA1-24750 was used in Western Blot to determine STMN1 function in the liver in vivo, in mice infected with a control or Stmn1-expressing adenovirus.
Wed Jan 01 00:00:00 UTC 2020
Stathmin 1 Induces Murine Hepatocyte Proliferation and Increased Liver Mass.
Hepatology communications
Zhao E,Shen Y,Amir M,Farris AB,Czaja MJ
MA1-24750 was used in Western Blot to determine STMN1 function in the liver in vivo, in mice infected with a control or Stmn1-expressing adenovirus.
Wed Jan 01 00:00:00 UTC 2020
The CDK4/CDK6 inhibitor PD0332991 paradoxically stabilizes activated cyclin D3-CDK4/6 complexes.
Cell cycle (Georgetown, Tex.)
Paternot S,Colleoni B,Bisteau X,Roger PP
MA1-24750 was used in Western Blot to study the differences in PD0332991 activity on the activation of cyclin D-CDK4/6 complexes, dependent on p21 binding.
Thu Aug 20 00:00:00 UTC 2015
Genetic characterization of the role of the Cip/Kip family of proteins as cyclin-dependent kinase inhibitors and assembly factors.
Molecular and cellular biology
Cerqueira A,Martín A,Symonds CE,Odajima J,Dubus P,Barbacid M,Santamaría D
MA1-24750 was used in western blot to study the role of Cip/Kip family members as Cdk inhibitors and assembly factors stabilizing Cdk4/6-cyclin D complexes
Tue Apr 01 00:00:00 UTC 2014
Apigenin inhibits prostate cancer progression in TRAMP mice via targeting PI3K/Akt/FoxO pathway.
Carcinogenesis
Shukla S,Bhaskaran N,Babcook MA,Fu P,Maclennan GT,Gupta S
MA1-24750 was used in western blot to study the role of PI3 kinase/Akt/FoxO signaling in the mechanism by which apigenin inhibits the progression of prostate cancer in a murine model
Sat Feb 01 00:00:00 UTC 2014
Aberrant expression pattern and location of cullin 1 are associated with the development of papillary carcinoma in thyroid and cyclin D1 expression.
Endocrine pathology
Do SI,Kim K,Lee H,Kim HS,Do TG,Yun J,Kim DH,Chae SW,Park YL,Park CH,Sohn JH,Min KW,Pyo JS
MA1-24750 was used in immunohistochemistry to study the immunohistochemical expression of Cullin-1 and cyclin D1 in patients with papillary thyroid carcinoma and the relationship to cliniopathology
Mon Sep 01 00:00:00 UTC 2014
SHIP2 signaling in normal and pathological situations: Its impact on cell proliferation.
Advances in biological regulation
Elong Edimo W,Schurmans S,Roger PP,Erneux C
MA1-24750 was used in western blot to study the roles of SHIP2 signaling in normal and tumor cells
Wed Jan 01 00:00:00 UTC 2014
WNT signaling and distant metastasis in colon cancer through transcriptional activity of nuclear β-Catenin depend on active PI3K signaling.
Oncotarget
Ormanns S,Neumann J,Horst D,Kirchner T,Jung A
MA1-24750 was used in western blot to learn how active PI3K signaling is required for WNT signaling and distant metastasis in colon cancer through nuclear beta-catenin transcriptional activity
Fri May 30 00:00:00 UTC 2014
Overexpression of β-catenin and cyclinD1 predicts a poor prognosis in ovarian serous carcinomas.
International journal of clinical and experimental pathology
Wang H,Wang H,Makki MS,Wen J,Dai Y,Shi Q,Liu Q,Zhou X,Wang J
MA1-24750 was used in immunohistochemistry to study the prognostic value of the immunohistochemical expression of beta-catenin and cyclin D1 in ovarian serous carcinomas
Fri Sep 05 00:00:00 UTC 2014
Acetylation-defective mutant of Pparγ is associated with decreased lipid synthesis in breast cancer cells.
Oncotarget
Tian L,Wang C,Hagen FK,Gormley M,Addya S,Soccio R,Casimiro MC,Zhou J,Powell MJ,Xu P,Deng H,Sauve AA,Pestell RG
MA1-24750 was used in western blot to determine that decreased lipid synthesis in breast cancer cells and its association with acetylated-defective mutant of Ppary
Mon Sep 15 00:00:00 UTC 2014
Nitric oxide production upregulates Wnt/β-catenin signaling by inhibiting Dickkopf-1.
Cancer research
Du Q,Zhang X,Liu Q,Zhang X,Bartels CE,Geller DA
MA1-24750 was used in western blot to study the role of Dickkopf-1 downregulation in the mechanism by which NO upregulates Wnt/beta-catenin signaling
Fri Nov 01 00:00:00 UTC 2013
Targeting cell cycle and hormone receptor pathways in cancer.
Oncogene
Comstock CE,Augello MA,Goodwin JF,de Leeuw R,Schiewer MJ,Ostrander WF,Burkhart RA,McClendon AK,McCue PA,Trabulsi EJ,Lallas CD,Gomella LG,Centenera MM,Brody JR,Butler LM,Tilley WD,Knudsen KE
MA1-24750 was used in western blot to study the antitumor properties and mechanistic functions of PD-0332991 in prostate cancer models
Thu Nov 28 00:00:00 UTC 2013
Cell cycle activation contributes to increased neuronal activity in the posterior thalamic nucleus and associated chronic hyperesthesia after rat spinal cord contusion.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
Wu J,Raver C,Piao C,Keller A,Faden AI
MA1-24750 was used in immunohistochemistry and western blot to study the role of cell cycle activation in spinal cord injury-associated pain via elevated posterior thalamic nucleus neuronal activity
Mon Jul 01 00:00:00 UTC 2013
UBE2QL1 is disrupted by a constitutional translocation associated with renal tumor predisposition and is a novel candidate renal tumor suppressor gene.
Human mutation
Wake NC,Ricketts CJ,Morris MR,Prigmore E,Gribble SM,Skytte AB,Brown M,Clarke N,Banks RE,Hodgson S,Turnell AS,Maher ER,Woodward ER
MA1-24750 was used in immunohistochemistry to study the association of the novel UBE2QL1 gene with renal cell carcinoma and its potential role as a renal tumor suppressor
Sun Dec 01 00:00:00 UTC 2013
Carboplatin delays mammary cancer 4T1 growth in mice.
Pathology, research and practice
Souza CM,Gamba Cde O,Campos CB,Lopes MT,Ferreira MA,Andrade SP,Cassali GD
MA1-24750 was used in immunohistochemistry to study the potential mechanisms by which carboplatin inhibits mammary tumor growth and metastasis in mice
Tue Jan 15 00:00:00 UTC 2013
'Monster cell' melanoma with pulmonary metastasis and cyclin D1 amplification.
Journal of cutaneous pathology
Hawryluk EB,Baran JL,Gerami P,Sepehr A
MA1-24750 was used in immunohistochemistry to report on a case of pulmonary 'monster cell' melanoma
Tue Jan 01 00:00:00 UTC 2013
Identification of microRNA-mRNA functional interactions in UVB-induced senescence of human diploid fibroblasts.
BMC genomics
Greussing R,Hackl M,Charoentong P,Pauck A,Monteforte R,Cavinato M,Hofer E,Scheideler M,Neuhaus M,Micutkova L,Mueck C,Trajanoski Z,Grillari J,Jansen-Dürr P
MA1-24750 was used in western blot to study induction of senescence in human diploid fibroblasts by UVB irradiation and the role of interactions between miRNAs and mRNAs in the underlying molecular mechanisms
Thu Apr 04 00:00:00 UTC 2013
Melatonin inhibits the proliferation of human osteosarcoma cell line MG-63.
Bone
Liu L,Xu Y,Reiter RJ
MA1-24750 was used in western blot to study the mechanism underlying the inhibition of human osteosarcoma cell line proliferation by melatonin
Thu Aug 01 00:00:00 UTC 2013
CDK4 T172 phosphorylation is central in a CDK7-dependent bidirectional CDK4/CDK2 interplay mediated by p21 phosphorylation at the restriction point.
PLoS genetics
Bisteau X,Paternot S,Colleoni B,Ecker K,Coulonval K,De Groote P,Declercq W,Hengst L,Roger PP
MA1-24750 was used in western blot to study the roles CDK7 and p21 in regulating the T172 phosphorylation of CDK4 at the restriction point
Wed May 01 00:00:00 UTC 2013
ChIP sequencing of cyclin D1 reveals a transcriptional role in chromosomal instability in mice.
The Journal of clinical investigation
Casimiro MC,Crosariol M,Loro E,Ertel A,Yu Z,Dampier W,Saria EA,Papanikolaou A,Stanek TJ,Li Z,Wang C,Fortina P,Addya S,Tozeren A,Knudsen ES,Arnold A,Pestell RG
MA1-24750 was used in western blot to study the role of cyclin D1 in chromosome instability and tumorigenesis as revealed by genome-wide ChIP analysis
Thu Mar 01 00:00:00 UTC 2012
The tumour suppressor FOXO3 is a key regulator of mantle cell lymphoma proliferation and survival.
British journal of haematology
Obrador-Hevia A,Serra-Sitjar M,Rodríguez J,Villalonga P,Fernández de Mattos S
MA1-24750 was used in western blot to study the modulation of mantle cell lymphoma growth and proliferation by FOXO3
Wed Feb 01 00:00:00 UTC 2012
Combined effect of cyclin D3 expression and abrogation of cyclin D1 prevent mouse skin tumor development.
Cell cycle (Georgetown, Tex.)
Wang X,Sistrunk C,Miliani de Marval PL,Kim Y,Rodriguez-Puebla ML
MA1-24750 was used in western blot to study the protective effect against skin cancer formation of cyclin D3 overexpression plus cyclin D1 ablation
Sun Jan 15 00:00:00 UTC 2012
The role of cyclin D1 expression and patient's survival in non-small-cell lung cancer: a systematic review with meta-analysis.
Clinical lung cancer
Zhang LQ,Jiang F,Xu L,Wang J,Bai JL,Yin R,Wu YQ,Meng LJ
MA1-24750 was used in immunohistochemistry to study the lack of prognostic value of cyclin D1 expression in non-small cell lung cancer patients
Tue May 01 00:00:00 UTC 2012
Synergistic Effect of Hyperglycemia and p27(kip1) Suppression on Adult Mouse Islet Beta Cell Replication.
International journal of endocrinology
Chen ST,Fu SH,Hsu S,Huang YY,Hsu BR
MA1-24750 was used in western blot to explore the contributions of hyperglycemia and p27(kip1) suppression on islet beta cell regeneration
Thu Aug 23 00:00:00 UTC 2012
EGFR inhibition in glioma cells modulates Rho signaling to inhibit cell motility and invasion and cooperates with temozolomide to reduce cell growth.
PloS one
Ramis G,Thomàs-Moyà E,Fernández de Mattos S,Rodríguez J,Villalonga P
MA1-24750 was used in western blot to study the role of Rho signaling in the mechanism by which inhibition of EGFR kinase activity impairs the motility and invasiveness of glioma cells
Thu Nov 08 00:00:00 UTC 2012
Notch receptor inhibition reveals the importance of cyclin D1 and Wnt signaling in invasive esophageal squamous cell carcinoma.
American journal of cancer research
Naganuma S,Whelan KA,Natsuizaka M,Kagawa S,Kinugasa H,Chang S,Subramanian H,Rhoades B,Ohashi S,Itoh H,Herlyn M,Diehl JA,Gimotty PA,Klein-Szanto AJ,Nakagawa H
MA1-24750 was used in immunohistochemistry to study the roles of Notch, cyclin D1 and Wnt in invasive esophageal squamous cell carcinoma
Tue Oct 02 00:00:00 UTC 2012
Disruption of the mouse protein tyrosine kinase 6 gene prevents STAT3 activation and confers resistance to azoxymethane.
Gastroenterology
Gierut J,Zheng Y,Bie W,Carroll RE,Ball-Kell S,Haegebarth A,Tyner AL
MA1-24750 was used in western blot to investigate the role of protein tyrosine kinase 6 in STAT3 activation and colon tumorigenesis.
Sat Oct 01 00:00:00 UTC 2011
Interaction between FGFR-2, STAT5, and progesterone receptors in breast cancer.
Cancer research
Cerliani JP,Guillardoy T,Giulianelli S,Vaque JP,Gutkind JS,Vanzulli SI,Martins R,Zeitlin E,Lamb CA,Lanari C
MA1-24750 was used in immunoprecipitation and western blot to study the interaction between FGFR-2, STAT5, and progesterone receptors in breast cancer
Sun May 15 00:00:00 UTC 2011
Melatonin delays cell proliferation by inducing G1 and G2 /M phase arrest in a human osteoblastic cell line hFOB 1.19.
Journal of pineal research
Liu L,Zhu Y,Xu Y,Reiter RJ
MA1-24750 was used in western blot to study the mechanism by which melatonin delays cell proliferation in a human osteoblastic cell line
Tue Mar 01 00:00:00 UTC 2011
Preclinical pharmacology, antitumor activity, and development of pharmacodynamic markers for the novel, potent AKT inhibitor CCT128930.
Molecular cancer therapeutics
Yap TA,Walton MI,Hunter LJ,Valenti M,de Haven Brandon A,Eve PD,Ruddle R,Heaton SP,Henley A,Pickard L,Vijayaraghavan G,Caldwell JJ,Thompson NT,Aherne W,Raynaud FI,Eccles SA,Workman P,Collins I,Garrett MD
MA1-24750 was used in western blot to study the anti-tumor activity, pharmacology and pharmacodynamics of a novel AKT inhibitor
Tue Feb 01 00:00:00 UTC 2011
Plk5, a polo box domain-only protein with specific roles in neuron differentiation and glioblastoma suppression.
Molecular and cellular biology
de Cárcer G,Escobar B,Higuero AM,García L,Ansón A,Pérez G,Mollejo M,Manning G,Meléndez B,Abad-Rodríguez J,Malumbres M
MA1-24750 was used in western blot to investigate the influence of Plk5 on the progress of brain cancer
Tue Mar 01 00:00:00 UTC 2011
Classical membrane progesterone receptors in murine mammary carcinomas: agonistic effects of progestins and RU-486 mediating rapid non-genomic effects.
Breast cancer research and treatment
Bottino MC,Cerliani JP,Rojas P,Giulianelli S,Soldati R,Mondillo C,Gorostiaga MA,Pignataro OP,Calvo JC,Gutkind JS,Molinolo AA,Lüthy IA,Lanari C
MA1-24750 was used in western blot to study the effect ofprogestins and RU-486 on murine mammary carcinoma
Fri Apr 01 00:00:00 UTC 2011
IDH1 and IDH2 mutations, immunohistochemistry and associations in a series of brain tumors.
Journal of neuro-oncology
Mellai M,Piazzi A,Caldera V,Monzeglio O,Cassoni P,Valente G,Schiffer D
MA1-24750 was used in immunohistochemistry to study the relationship between IDH1 and IDH2 mutations and a series of brain tumors
Tue Nov 01 00:00:00 UTC 2011
Metabotropic glutamate receptor 5 promotes proliferation of human neural stem/progenitor cells with activation of mitogen-activated protein kinases signaling pathway in vitro.
Neuroscience
Zhao L,Jiao Q,Yang P,Chen X,Zhang J,Zhao B,Zheng P,Liu Y
MA1-24750 was used in western blot to study the mechanism by which mGluR5 promotes human embryonic neural stem/progenitor cell proliferation
Thu Sep 29 00:00:00 UTC 2011
Hepatic carcinoma-associated fibroblasts promote an adaptative response in colorectal cancer cells that inhibit proliferation and apoptosis: nonresistant cells die by nonapoptotic cell death.
Neoplasia (New York, N.Y.)
Berdiel-Acer M,Bohem ME,López-Doriga A,Vidal A,Salazar R,Martínez-Iniesta M,Santos C,Sanjuan X,Villanueva A,Molleví DG
MA1-24750 was used in western blot to study the adaptive response promoted by hepatic carcinoma-associated fibroblasts in colorectal cancer cells
Sat Oct 01 00:00:00 UTC 2011
The adaptive compensations in endocrine pancreas from glucocorticoid-treated rats are reversible after the interruption of treatment.
Acta physiologica (Oxford, England)
Rafacho A,Quallio S,Ribeiro DL,Taboga SR,Paula FM,Boschero AC,Bosqueiro JR
MA1-24750 was used in western blot to study whether the glucocorticoid induced effects on insulin resistance and insulin secretion are reversible
Mon Nov 01 00:00:00 UTC 2010
1 Alpha,25-dihydroxyvitamin D3 and its TX527 analog inhibit the growth of endothelial cells transformed by Kaposi sarcoma-associated herpes virus G protein-coupled receptor in vitro and in vivo.
Endocrinology
Gonzalez-Pardo V,Martin D,Gutkind JS,Verstuyf A,Bouillon R,de Boland AR,Boland RL
MA1-24750 was used in western blot to investigate the effect of 1 alpha,25-dihydroxyvitamin D3 and its TX527 analog on endothelial cell proliferation
Fri Jan 01 00:00:00 UTC 2010
AMN082 promotes the proliferation and differentiation of neural progenitor cells with influence on phosphorylation of MAPK signaling pathways.
Neurochemistry international
Tian Y,Liu Y,Chen X,Kang Q,Zhang J,Shi Q,Zhang H
MA1-24750 was used in western blot to investigate the role of metabotropic glutamate receptors in the development and differentiation of neural progenitors
Sun Aug 01 00:00:00 UTC 2010
Expression of cyclin D2 is an independent predictor of the development of hepatic metastasis in colorectal cancer.
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
Sarkar R,Hunter IA,Rajaganeshan R,Perry SL,Guillou P,Jayne DG
MA1-24750 was used in immunohistochemistry to investigate the prognostic significance cyclin D2 expression in liver metastasis
Thu Apr 01 00:00:00 UTC 2010
Hypoxia stimulates proliferation of rat neural stem cells with influence on the expression of cyclin D1 and c-Jun N-terminal protein kinase signaling pathway in vitro.
Neuroscience
Chen X,Tian Y,Yao L,Zhang J,Liu Y
MA1-24750 was used in western blot to investigate the effect of hypoxia on cyclin D1 expression and cell growth in rat neural stem cells
Wed Feb 03 00:00:00 UTC 2010
Norcantharidin inhibits growth of human gallbladder carcinoma xenografted tumors in nude mice by inducing apoptosis and blocking the cell cycle in vivo.
Hepatobiliary & pancreatic diseases international : HBPD INT
Fan YZ,Zhao ZM,Fu JY,Chen CQ,Sun W
MA1-24750 was used in immunohistochemistry to investigate the inhibitory effect of norcantharidin on the tumor growth of human gallbladder carcinoma xenografted in nude mice in vivo
Sun Aug 01 00:00:00 UTC 2010
Sansalvamide induces pancreatic cancer growth arrest through changes in the cell cycle.
Anticancer research
Heiferman MJ,Salabat MR,Ujiki MB,Strouch MJ,Cheon EC,Silverman RB,Bentrem DJ
MA1-24750 was used in western blot to investigate the antiproliferative effects of sansalvamide 12 in AsPC-1 and CD18 cells and its mechanism
Fri Jan 01 00:00:00 UTC 2010
Identification of a potent natural triterpenoid inhibitor of proteosome chymotrypsin-like activity and NF-kappaB with antimyeloma activity in vitro and in vivo.
Blood
Tiedemann RE,Schmidt J,Keats JJ,Shi CX,Zhu YX,Palmer SE,Mao X,Schimmer AD,Stewart AK
MA1-24750 was used in western blot to screen for compounds that suppress cyclin D2 promoter transcription
Thu Apr 23 00:00:00 UTC 2009
Multiple division cycles and long-term survival of hepatocytes are distinctly regulated by extracellular signal-regulated kinases ERK1 and ERK2.
Hepatology (Baltimore, Md.)
Frémin C,Bessard A,Ezan F,Gailhouste L,Régeard M,Le Seyec J,Gilot D,Pagès G,Pouysségur J,Langouët S,Baffet G
MA1-24750 was used in western blot to study the distinct roles of ERK1 and ERK2 in regulating the cell cycle and long-term survival in normal hepatocytes
Sun Mar 01 00:00:00 UTC 2009
Inhibition of integrin-linked kinase attenuates renal interstitial fibrosis.
Journal of the American Society of Nephrology : JASN
Li Y,Tan X,Dai C,Stolz DB,Wang D,Liu Y
MA1-24750 was used in western blot to investigate the influence of integrin-linked kinase inhibition on renal interstitial fibrosis
Tue Sep 01 00:00:00 UTC 2009
Differential response of glioma cells to FOXO1-directed therapy.
Cancer research
Lau CJ,Koty Z,Nalbantoglu J
MA1-24750 was used in western blot to examine the therapeutic significance of FOXO1 in glioma
Wed Jul 01 00:00:00 UTC 2009
Pifithrin-alpha protects against DNA damage-induced apoptosis downstream of mitochondria independent of p53.
Cell death and differentiation
Sohn D,Graupner V,Neise D,Essmann F,Schulze-Osthoff K,Jänicke RU
MA1-24750 was used in western blot to study the mechanism by which pifithrin-alpha protects against apoptosis induced by DNA damage
Mon Jun 01 00:00:00 UTC 2009
Relationship of phospho-pRb (Ser-807/811) level to exposure to tobacco smoke in primary non-small cell lung cancer.
Cancer letters
Ko E,Kim Y,Lee BB,Han J,Song SY,Shim YM,Park J,Kim DH
MA1-24750 was used in immunohistochemistry to study the relationship between levels of phosphorylated retinoblastoma protein and exposure to tobacco smoke in primary non-small cell lung cancer
Wed Feb 18 00:00:00 UTC 2009
PCDH24-induced contact inhibition involves downregulation of beta-catenin signaling.
Molecular oncology
Ose R,Yanagawa T,Ikeda S,Ohara O,Koga H
MA1-24750 was used in western blot to investigate the mechanism for contact inhibition induced by PCDH24 overexpression
Sun Feb 01 00:00:00 UTC 2009
E2F4 and ribonucleotide reductase mediate S-phase arrest in colon cancer cells treated with chlorophyllin.
International journal of cancer
Chimploy K,Díaz GD,Li Q,Carter O,Dashwood WM,Mathews CK,Williams DE,Bailey GS,Dashwood RH
MA1-24750 was used in western blot to investigate the cellular effects of chlorophyllin treatment
Sun Nov 01 00:00:00 UTC 2009
Interleukin-24 induces expression of beta4 integrin but suppresses anchorage-independent growth of rat mammary tumor cells by a mechanism that is independent of beta4.
Molecular cancer research : MCR
Xuan W,Li YJ,Liu G,Ben-David Y,Archer MC
MA1-24750 was used in western blot to study the role of IL-24 in beta4 integrin expression and suppression of rat mammary tumor cell growth
Sun Mar 01 00:00:00 UTC 2009
High doses of dexamethasone induce increased beta-cell proliferation in pancreatic rat islets.
American journal of physiology. Endocrinology and metabolism
Rafacho A,Cestari TM,Taboga SR,Boschero AC,Bosqueiro JR
MA1-24750 was used in western blot to study the effects of high dose dexamethasone on pancreatic beta-cell proliferation
Wed Apr 01 00:00:00 UTC 2009
Immunophenotypic analysis of CD103+ B-lymphoproliferative disorders: hairy cell leukemia and its mimics.
American journal of clinical pathology
Dong HY,Weisberger J,Liu Z,Tugulea S
MA1-24750 was used in immunohistochemistry to study the immunophenotype of CD103+ B-lymphoproliferative disorders
Wed Apr 01 00:00:00 UTC 2009
Eukaryotic initiation factor-4E and cyclin D1 expression associated with patient survival in lung cancer.
Clinical lung cancer
Khoury T,Alrawi S,Ramnath N,Li Q,Grimm M,Black J,Tan D
MA1-24750 was used in immunohistochemistry to study the prognostic value of initiation factor-4E and cyclin D1 expression in lung cancer
Thu Jan 01 00:00:00 UTC 2009
Cyclin A is essential for the p53-modulated inhibition from benzo(a)pyrene toxicity in A549 cells.
Toxicology
Wang Z,Qi Y,Chen Q,Yang D,Tang S,Jin X,Gao J,Fu J,Zhou Z,Wang J,Xiao X
MA1-24750 was used in western blot to study the role of cyclin A in the protective effect of p53 from benzopyrene carcinogenic toxicity in A549 cells
Wed Feb 04 00:00:00 UTC 2009
Transcription factor signal transducer and activator of transcription 5 promotes growth of human prostate cancer cells in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research
Dagvadorj A,Kirken RA,Leiby B,Karras J,Nevalainen MT
MA1-24750 was used in western blot to study the mechanism by which STAT5 promotes human prostate cancer cell growth
Sat Mar 01 00:00:00 UTC 2008
BAF180 is a critical regulator of p21 induction and a tumor suppressor mutated in breast cancer.
Cancer research
Xia W,Nagase S,Montia AG,Kalachikov SM,Keniry M,Su T,Memeo L,Hibshoosh H,Parsons R
MA1-24750 was used in western blot to study the role of BAF180 in regulating p21 expression in breast cancer
Sat Mar 15 00:00:00 UTC 2008
The Smo/Smo model: hedgehog-induced medulloblastoma with 90% incidence and leptomeningeal spread.
Cancer research
Hatton BA,Villavicencio EH,Tsuchiya KD,Pritchard JI,Ditzler S,Pullar B,Hansen S,Knoblaugh SE,Lee D,Eberhart CG,Hallahan AR,Olson JM
MA1-24750 was used in immunohistochemistry to evaluate a medulloblastoma murine model
Sat Mar 15 00:00:00 UTC 2008
Deregulated expression of p16INK4a and p53 pathway members in benign and malignant myoepithelial tumours of the salivary glands.
Histopathology
Vékony H,Röser K,Löning T,Raaphorst FM,Leemans CR,Van der Waal I,Bloemena E
MA1-24750 was used in immunohistochemistry to study the expression of p16INK4a and p53 pathway members in benign and malignant myoepithelial salivary gland tumours
Mon Dec 01 00:00:00 UTC 2008
Carcinoma-associated fibroblasts activate progesterone receptors and induce hormone independent mammary tumor growth: A role for the FGF-2/FGFR-2 axis.
International journal of cancer
Giulianelli S,Cerliani JP,Lamb CA,Fabris VT,Bottino MC,Gorostiaga MA,Novaro V,Góngora A,Baldi A,Molinolo A,Lanari C
MA1-24750 was used in western blot to study the role of cancer-associated fibroblasts in mammary tumorigenesis and development of hormone independence
Mon Dec 01 00:00:00 UTC 2008
CCND1 polymorphisms (A870G and C1722G) modulate its protein expression and survival in oral carcinoma.
Oral oncology
Sathyan KM,Nalinakumari KR,Abraham T,Kannan S
MA1-24750 was used in immunohistochemistry to study the role of CCND1 polymorphisms in modulating its expression and survival in oral carcinoma
Tue Jul 01 00:00:00 UTC 2008
Functions of p21 and p27 in the regenerating epithelial linings of the mouse small and large intestine.
Cancer biology & therapy
Zheng Y,Bie W,Yang R,Perekatt AO,Poole AJ,Tyner AL
MA1-24750 was used in western blot to investigate the role of p21 and p27 in intestinal epithelial regeneraton
Sun Jun 01 00:00:00 UTC 2008
An acidic environment changes cyclin D1 localization and alters colony forming ability in gliomas.
Journal of neuro-oncology
Schnier JB,Nishi K,Harley WR,Gorin FA
MA1-24750 was used in western blot to investigate the influence of environmental pH on cyclin D1 localization and glioma proliferation
Fri Aug 01 00:00:00 UTC 2008
TRPM6 expression and cell proliferation are up-regulated by phosphorylation of ERK1/2 in renal epithelial cells.
Biochemical and biophysical research communications
Ikari A,Okude C,Sawada H,Yamazaki Y,Sugatani J,Miwa M
MA1-24750 was used in western blot to study the role of ERK1/2 phosphorylation in upregulating TRPM6 expression and cell proliferation in renal epithelial cells
Fri May 16 00:00:00 UTC 2008
The Ets transcription factor GABP is required for cell-cycle progression.
Nature cell biology
Yang ZF,Mott S,Rosmarin AG
MA1-24750 was used in western blot to study the role of Ets transcription factor GABP during cell-cycle progression
Thu Mar 01 00:00:00 UTC 2007
Proliferation and migration mediated by Dkk-1/Wnt/beta-catenin cascade in a model of hepatocellular carcinoma cells.
Translational research : the journal of laboratory and clinical medicine
Qin X,Zhang H,Zhou X,Wang C,Zhang H,Zhang X,Ye L
MA1-24750 was used in western blot to investigate the role of Dkk-1/Wnt/beta-catenin pathway in the tumorigenesis and metastasis of hepatocellular carcinoma
Thu Nov 01 00:00:00 UTC 2007
Poorly differentiated follicular thyroid carcinoma: prognostic factors and relevance of histological classification.
Thyroid : official journal of the American Thyroid Association
Pulcrano M,Boukheris H,Talbot M,Caillou B,Dupuy C,Virion A,De Vathaire F,Schlumberger M
MA1-24750 was used in immunohistochemistry to study the prognosis and histological classification of poorly differentiated follicular thyroid carcinoma
Sun Jul 01 00:00:00 UTC 2007
Hemangiomas and angiosarcomas of the breast: diagnostic utility of cell cycle markers with emphasis on Ki-67.
Archives of pathology & laboratory medicine
Shin SJ,Lesser M,Rosen PP
MA1-24750 was used in immunohistochemistry to investigate the diagnostic markers for hemangiomas and angiosarcomas of the breast
Sun Apr 01 00:00:00 UTC 2007
Improved clonality assessment in germinal centre/post-germinal centre non-Hodgkin's lymphomas with high rates of somatic hypermutation.
Journal of clinical pathology
Catherwood MA,Gonzalez D,Patton C,Dobbin E,Venkatraman L,Alexander HD
MA1-24750 was used in immunohistochemistry to examine the effect of high rates of somatic hypermutation in germinal centre/post-germinal centre non-Hodgkin lymphomas on the clonality assessment
Tue May 01 00:00:00 UTC 2007
Cell cycle arrest by the isoprenoids perillyl alcohol, geraniol, and farnesol is mediated by p21(Cip1) and p27(Kip1) in human pancreatic adenocarcinoma cells.
The Journal of pharmacology and experimental therapeutics
Wiseman DA,Werner SR,Crowell PL
MA1-24750 was used in western blot to study the role of p21(Cip1) and p27(Kip1) in the induction of cell cycle arrest in human panceatic adenocarcinoma cells by isoprenoids
Thu Mar 01 00:00:00 UTC 2007
Hydrocortisone and indomethacin negatively modulate EGF-R signaling in human fetal intestine.
Pediatric research
Kajanne R,Leppä S,Luukkainen P,Ustinov J,Thiel A,Ristimäki A,Miettinen PJ
MA1-24750 was used in western blot to examine if EGF-R contributes to the hydrocortisone and indomethacin-induced intestinal perforations of preterm infants
Thu Nov 01 00:00:00 UTC 2007
The over-expression of p53 H179Y residue mutation causes the increase of cyclin A1 and Cdk4 expression in HELF cells.
Molecular and cellular biochemistry
Yang D,Qi Y,Chen Q,Wang Z,Jin X,Gao J,Fu J,Xiao X,Zhou Z
MA1-24750 was used in western blot to investigate the effect of the overexpression of p53 H179Y residue mutation on the expression of cyclin A1 and Cdk4 in HELF cells
Mon Oct 01 00:00:00 UTC 2007
The significance of Ki-67 proliferative index and cyclin D1 expression of dysplastic nevi in the biologic spectrum of melanocytic lesions.
Applied immunohistochemistry & molecular morphology : AIMM
Lebe B,Pabuççuoğlu U,Ozer E
MA1-24750 was used in immunohistochemistry to study Ki-67 proliferative index and cyclin D1 expression of dysplastic nevi and its significance for melanoma development
Fri Jun 01 00:00:00 UTC 2007
The role of p28GANK in rat oval cells activation and proliferation.
Liver international : official journal of the International Association for the Study of the Liver
Shan YF,Zhou WP,Fu XY,Yan HX,Yang W,Liu SQ,Cao HF,Kang B,Wu MC,Wang HY
MA1-24750 was used in western blot to investigate the importance of p28GANK in the activation and proliferation of rat oval cells
Wed Mar 01 00:00:00 UTC 2006
Lymphoid neoplasms associated with concurrent t(14;18) and 8q24/c-MYC translocation generally have a poor prognosis.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Kanungo A,Medeiros LJ,Abruzzo LV,Lin P
MA1-24750 was used in immunohistochemistry to study the prognostic value of concurrent t(14;18) and 8q24/c-MYC translocation in lymphoid neoplasms
Sun Jan 01 00:00:00 UTC 2006
Stimulation of pancreatic beta-cell replication by incretins involves transcriptional induction of cyclin D1 via multiple signalling pathways.
The Journal of endocrinology
Friedrichsen BN,Neubauer N,Lee YC,Gram VK,Blume N,Petersen JS,Nielsen JH,Møldrup A
MA1-24750 was used in western blot to study the mechanisms by which incretins stimulate pancreatic beta-cell replication
Wed Mar 01 00:00:00 UTC 2006
Correlation of cyclin D1 and cyclin D3 overexpression with the loss of PTEN expression in endometrial carcinoma.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
Wu W,Slomovitz BM,Soliman PT,Schmeler KM,Celestino J,Milam MR,Lu KH
MA1-24750 was used in immunohistochemistry to study whether cyclin D1 and D3 overexpression is correlated with PTEN inactivation in endometrioid endometrial cancer
Tue Dec 05 00:00:00 UTC 2006
Intrasinusoidal bone marrow infiltration and splenic marginal zone lymphoma: a quantitative study.
European journal of haematology
Pich A,Fraire F,Fornari A,Bonino LD,Godio L,Bortolin P,Chiusa L,Palestro G
MA1-24750 was used in immunohistochemistry to study whether the amount of intrasinusoidal bone marrow infiltration is diagnostic of splenic marginal zone lymphoma
Mon May 01 00:00:00 UTC 2006
HIV-1 Tat regulates endothelial cell cycle progression via activation of the Ras/ERK MAPK signaling pathway.
Molecular biology of the cell
Toschi E,Bacigalupo I,Strippoli R,Chiozzini C,Cereseto A,Falchi M,Nappi F,Sgadari C,Barillari G,Mainiero F,Ensoli B
MA1-24750 was used in western blot to study the mechanism by which HIV1 tat regulates endothelial cell cycle progression
Sat Apr 01 00:00:00 UTC 2006
Differential utilization of cyclin D1 and cyclin D3 in the distinct mitogenic stimulations by growth factors and TSH of human thyrocytes in primary culture.
Molecular endocrinology (Baltimore, Md.)
Paternot S,Dumont JE,Roger PP
MA1-24750 was used in western blot to study the roles of cyclin D1 and cyclin D3 in different mitogenic modes of human thyrocytes
Fri Dec 01 00:00:00 UTC 2006
Urinary podocyte loss is a more specific marker of ongoing glomerular damage than proteinuria.
Journal of the American Society of Nephrology : JASN
Yu D,Petermann A,Kunter U,Rong S,Shankland SJ,Floege J
MA1-24750 was used in immunohistochemistry to compare the specificity of urinary podocyte loss versus proteinurea as markers of ongoing glomerular damage
Wed Jun 01 00:00:00 UTC 2005
In vitro and in vivo pharmacokinetic-pharmacodynamic relationships for the trisubstituted aminopurine cyclin-dependent kinase inhibitors olomoucine, bohemine and CYC202.
Clinical cancer research : an official journal of the American Association for Cancer Research
Raynaud FI,Whittaker SR,Fischer PM,McClue S,Walton MI,Barrie SE,Garrett MD,Rogers P,Clarke SJ,Kelland LR,Valenti M,Brunton L,Eccles S,Lane DP,Workman P
MA1-24750 was used in western blot to study the pharmacokinetics and pharmacodynamics of three tri-substituted aminopurine Cdk inhibitors in a model of colon carcinoma
Fri Jul 01 00:00:00 UTC 2005
Absence of IHH and retention of PTHrP signalling in enchondromas and central chondrosarcomas.
The Journal of pathology
Rozeman LB,Hameetman L,Cleton-Jansen AM,Taminiau AH,Hogendoorn PC,Bovée JV
MA1-24750 was used in immunohistochemistry to study the absence of IHH and retention of PTHrP signalling in enchondromas and central chondrosarcomas
Tue Mar 01 00:00:00 UTC 2005
Expression of D-type cyclins in colon cancer and in cell lines from colon carcinomas.
British journal of cancer
Mermelshtein A,Gerson A,Walfisch S,Delgado B,Shechter-Maor G,Delgado J,Fich A,Gheber L
MA1-24750 was used in western blot to study the expression of cyclins D1, D2 and D3 in colon cancer and their role in carcinogenesis
Mon Aug 08 00:00:00 UTC 2005
Coordinated expression of cyclin D1 and LEF-1/TCF transcription factor is restricted to a subset of hepatocellular carcinoma.
Liver international : official journal of the International Association for the Study of the Liver
Schmitt-Graeff A,Ertelt-Heitzmann V,Allgaier HP,Olschewski M,Nitschke R,Haxelmans S,Koelble K,Behrens J,Blum HE
MA1-24750 was used in immunohistochemistry to study the coordinated expression of cyclin D1 and LEF-1/TCF transcription factors in a subset of hepatocellular carcinoma
Mon Aug 01 00:00:00 UTC 2005
Differential effects of 16alpha-hydroxyestrone and 2-methoxyestradiol on cyclin D1 involving the transcription factor ATF-2 in MCF-7 breast cancer cells.
Journal of molecular endocrinology
Lewis JS,Thomas TJ,Pestell RG,Albanese C,Gallo MA,Thomas T
MA1-24750 was used in western blot to study the effect of two metabolites of estradiol on DNA synthesis, cell cycle progression and cyclin D1 protein levels in estrogen receptor-positive MCF-7 cells
Tue Feb 01 00:00:00 UTC 2005
Indian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiation.
Nature genetics
van den Brink GR,Bleuming SA,Hardwick JC,Schepman BL,Offerhaus GJ,Keller JJ,Nielsen C,Gaffield W,van Deventer SJ,Roberts DJ,Peppelenbosch MP
MA1-24750 was used in western blot to study the roles of Indian Hedgehog and Wnt signaling in colonic epithelial cell differentiation
Mon Mar 01 00:00:00 UTC 2004
Overexpression of the colony-stimulating factor (CSF-1) and/or its receptor c-fms in mammary glands of transgenic mice results in hyperplasia and tumor formation.
Cancer research
Kirma N,Luthra R,Jones J,Liu YG,Nair HB,Mandava U,Tekmal RR
MA1-24750 was used in western blot to study the roles of CSF-1 and its receptor c-fms in hyperplasia and tumor formation
Tue Jun 15 00:00:00 UTC 2004
Skp2-dependent degradation of p27kip1 is essential for cell cycle progression.
Genes & development
Kossatz U,Dietrich N,Zender L,Buer J,Manns MP,Malek NP
MA1-24750 was used in western blot to study the essential role of Skp2-dependent degradation of p27kip1 in cell cycle progression
Mon Nov 01 00:00:00 UTC 2004
Differential expression of the calcium sensing receptor and combined loss of chromosomes 1q and 11q in parathyroid carcinoma.
The Journal of pathology
Haven CJ,van Puijenbroek M,Karperien M,Fleuren GJ,Morreau H
MA1-24750 was used in immunohistochemistry to study the expression of the calcium sensing receptor and loss of chromosomes 1q and 11q in parathyroid carcinoma
Thu Jan 01 00:00:00 UTC 2004
Cdk6-cyclin D3 activity in murine ES cells is resistant to inhibition by p16(INK4a).
Oncogene
Faast R,White J,Cartwright P,Crocker L,Sarcevic B,Dalton S
MA1-24750 was used in western blot to study the resistance of embryonic stem cell Cdk6-cyclin D3 complexes to inhibition by p16(INK4a)
Thu Jan 15 00:00:00 UTC 2004
p53, p16 and cyclin D1: molecular determinants of radiotherapy treatment response in oral carcinoma.
International journal of cancer
Jayasurya R,Francis G,Kannan S,Lekshminarayanan K,Nalinakumari KR,Abraham T,Abraham EK,Nair MK
MA1-24750 was used in immunohistochemistry to study the molecular determinants of the response to radiotherapy in oral carcinoma
Sat May 01 00:00:00 UTC 2004
ILK is required for the assembly of matrix-forming adhesions and capillary morphogenesis in endothelial cells.
Journal of cell science
Vouret-Craviari V,Boulter E,Grall D,Matthews C,Van Obberghen-Schilling E
MA1-24750 was used in western blot to study the role of ILK during the assembly of matrix-forming adhesions and capillary morphogenesis in endothelial cells
Wed Sep 01 00:00:00 UTC 2004
Role of the phosphatidylinositol 3'-kinase-Akt signal pathway in the proliferation of human pancreatic ductal carcinoma cell lines.
Pancreas
Takeda A,Osaki M,Adachi K,Honjo S,Ito H
MA1-24750 was used in western blot to study the proliferation of human pancreatic ductal carcinoma cell lines and the role played by the the PI3 kinase-Akt pathway
Thu Apr 01 00:00:00 UTC 2004
Subchronic exposure to arsenic through drinking water alters expression of cancer-related genes in rat liver.
Toxicologic pathology
Cui X,Li S,Shraim A,Kobayashi Y,Hayakawa T,Kanno S,Yamamoto M,Hirano S
MA1-24750 was used in immunohistochemistry to study the effect of sub-chronic arsenic exposure om the expression of cancer-related genes in rat liver
Tue Sep 28 00:00:00 UTC 2004
Trichostatin A induces differential cell cycle arrests but does not induce apoptosis in primary cultures of mitogen-stimulated rat hepatocytes.
Journal of hepatology
Papeleu P,Loyer P,Vanhaecke T,Elaut G,Geerts A,Guguen-Guillouzo C,Rogiers V
MA1-24750 was used in western blot to study the effect of Trichostatin A on the proliferation and survival of primary cultures of mitogen-stimulated hepatocytes
Mon Sep 01 00:00:00 UTC 2003
Cyclooxygenase 2 expression and molecular alterations in Peutz-Jeghers hamartomas and carcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research
De Leng WW,Westerman AM,Weterman MA,De Rooij FW,Dekken Hv Hv,De Goeij AF,Gruber SB,Wilson JH,Offerhaus GJ,Giardiello FM,Keller JJ
MA1-24750 was used in immunohistochemistry to study the expression of cyclooxygenase 2 and molecular alterations in Peutz-Jeghers hamartomas and carcinomas
Fri Aug 01 00:00:00 UTC 2003
Expression of angiotensin type II receptor downregulates Cdk4 synthesis and inhibits cell-cycle progression.
Oncogene
Gingras B,Rodier G,Giasson E,Coulombe P,Chassagne C,Meloche S
MA1-24750 was used in western blot to study the role of angiotensin II receptor expression in Cdk4 downregulation and inhibition of cell proliferation
Thu May 01 00:00:00 UTC 2003
Differences in the pathologic and molecular features of intraductal breast carcinoma between younger and older women.
Cancer
Rodrigues NA,Dillon D,Carter D,Parisot N,Haffty BG
MA1-24750 was used in immunohistochemistry to study the effect of age on the pathologic and molecular features of intraductal breast carcinoma
Sat Mar 15 00:00:00 UTC 2003
G3139 (oblimersen) may inhibit prostate cancer cell growth in a partially bis-CpG-dependent non-antisense manner.
Molecular cancer therapeutics
Lai JC,Benimetskaya L,Santella RM,Wang Q,Miller PS,Stein CA
MA1-24750 was used in western blot to study the contribution of a bis-CpG-dependent non-antisense mechanism to the inibition of prostate cancer cell growth by oblimersen
Wed Oct 01 00:00:00 UTC 2003
Alterations of beta-catenin pathway in non-melanoma skin tumors: loss of alpha-ABC nuclear reactivity correlates with the presence of beta-catenin gene mutation.
The American journal of pathology
Doglioni C,Piccinin S,Demontis S,Cangi MG,Pecciarini L,Chiarelli C,Armellin M,Vukosavljevic T,Boiocchi M,Maestro R
MA1-24750 was used in immunohistochemistry to investigate the beta-catenin pathway in non-melanoma skin tumors
Mon Dec 01 00:00:00 UTC 2003
Roles of mitogen-activated protein kinase and phosphoinositide 3'-kinase in ErbB2/ErbB3 coreceptor-mediated heregulin signaling.
Experimental cell research
Vijapurkar U,Kim MS,Koland JG
MA1-24750 was used in western blot to study the roles of MAP kinase and PI3 kinase in heregulin signaling mediated via the ErbB2/ErbB3 co-receptor
Tue Apr 01 00:00:00 UTC 2003
Validation of tissue array technology in head and neck squamous cell carcinoma.
Head & neck
Chen B,van den Brekel MW,Buschers W,Balm AJ,van Velthuysen ML
MA1-24750 was used in immunohistochemistry to evaluate the use of tissue array technology to analyse archived head and neck cancer tissue samples
Sat Nov 01 00:00:00 UTC 2003
Cyclin D2 compensates for the loss of cyclin D1 in estrogen-induced mouse uterine epithelial cell proliferation.
Molecular endocrinology (Baltimore, Md.)
Chen B,Pollard JW
MA1-24750 was used in western blot to study the ability of cyclin D2 to compensate for cyclin D1 loss in estrogen-induced mouse uterine epithelial cell proliferation
Tue Jul 01 00:00:00 UTC 2003
Signal transducer and activator of transcription 5 activation is sufficient to drive transcriptional induction of cyclin D2 gene and proliferation of rat pancreatic beta-cells.
Molecular endocrinology (Baltimore, Md.)
Friedrichsen BN,Richter HE,Hansen JA,Rhodes CJ,Nielsen JH,Billestrup N,Møldrup A
MA124750 was used in western blot to study the role of STAT5 in transcriptional induction of the cyclin D2 gene and proliferation of rat pancreatic beta-cells
Thu May 01 00:00:00 UTC 2003
Differential effects of p21(WAF1/CIP1) deficiency on MMTV-ras and MMTV-myc mammary tumor properties.
Cancer research
Bearss DJ,Lee RJ,Troyer DA,Pestell RG,Windle JJ
MA1-24750 was used in western blot to study the role of the CDK inhibitor p21(WAF1/CIP1) in tumor suppression in MMTV-ras and MMTV-myc transgenic mice
Mon Apr 01 00:00:00 UTC 2002
Rapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells.
Molecular and cellular biology
Law BK,Chytil A,Dumont N,Hamilton EG,Waltner-Law ME,Aakre ME,Covington C,Moses HL
MA1-24750 was used in western blot to study the mechanism by which rapamycin potentiates TGFbeta-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells
Sun Dec 01 00:00:00 UTC 2002
Another case of mantle cell lymphoma presenting as breast masses.
Journal of clinical pathology
Fadare O,Shukla P
MA1-24750 was used in immunohistochemistry to report on a case of mantle cell lymphoma presenting as breast masses
Thu Aug 01 00:00:00 UTC 2002
Stage-dependent activation of cell cycle and apoptosis mechanisms in the right ventricle by pressure overload.
Biochimica et biophysica acta
Ecarnot-Laubriet A,Assem M,Poirson-Bichat F,Moisant M,Bernard C,Lecour S,Solary E,Rochette L,Teyssier JR
MA1-24750 was used in immunohistochemistry to study the role of apoptosis and aberrant cell cycle re-entry in the vulnerability of the right ventricle to pressure overload
Wed Apr 24 00:00:00 UTC 2002
Analysis of C-MYC function in normal cells via conditional gene-targeted mutation.
Immunity
de Alboran IM,O'Hagan RC,Gärtner F,Malynn B,Davidson L,Rickert R,Rajewsky K,DePinho RA,Alt FW
MA1-24750 was used in western blot to study C-MYC function in mouse embryonic fibroblasts and mature B lymphocytes
Mon Jan 01 00:00:00 UTC 2001
Overexpression of aromatase leads to hyperplasia and changes in the expression of genes involved in apoptosis, cell cycle, growth, and tumor suppressor functions in the mammary glands of transgenic mice.
Cancer research
Kirma N,Gill K,Mandava U,Tekmal RR
MA1-24750 was used in western blot to study the role of aromatase in the biochemical pathways leading to mammary tumorigenesis in transgenic mice
Thu Mar 01 00:00:00 UTC 2001
Analysis of the transcriptional program induced by Raf in epithelial cells.
Genes & development
Schulze A,Lehmann K,Jefferies HB,McMahon M,Downward J
MA1-24750 was used in western blot to study the transcriptional program induced by Raf in epithelial cells
Sun Apr 15 00:00:00 UTC 2001
Telomerase activation cooperates with inactivation of p16 in early head and neck tumorigenesis.
British journal of cancer
Soria JC,Morat L,Commo F,Dabit D,Perie S,Sabatier L,Fouret P
MA1-24750 was used in immunohistochemistry to investigate the interplay between telomerase activation and p16 inactivation during the early head and neck tumorigenesis
Thu Feb 01 00:00:00 UTC 2001
Loss of p16(INK4a) expression correlates with decreased survival in pediatric osteosarcomas.
International journal of cancer
Maitra A,Roberts H,Weinberg AG,Geradts J
MA1-24750 was used in immunohistochemistry to study the prognostic significance of loss of p16(INK4a) expression in pediatric osteosarcomas
Sat Jan 20 00:00:00 UTC 2001
Large cell variants of CD5+, CD23- B-cell lymphoma/leukemia.
Archives of pathology & laboratory medicine
Dunphy CH,Perkins SL
MA1-24750 was used in immunohistochemistry to study 19 cases of large-cell variants of CD5+/CD23- B-cell lymphoma/leukemia
Sun Apr 01 00:00:00 UTC 2001
Genetic evidence for the interactions of cyclin D1 and p27(Kip1) in mice.
Molecular and cellular biology
Tong W,Pollard JW
MA1-24750 was used in immunoprecipitation to study the interactions of cyclin D1 and p27(Kip1) using knockout mice
Thu Feb 01 00:00:00 UTC 2001
Metabolic stabilization of p27 in senescent fibroblasts correlates with reduced expression of the F-box protein Skp2.
Experimental gerontology
Wagner M,Hampel B,Hütter E,Pfister G,Krek W,Zwerschke W,Jansen-Dürr P
MA1-24750 was used in western blot to study the correlation of p27(KIP1) accumulation in senescent fibroblasts with reduced levels of the F-box protein Skp2
Sat Dec 01 00:00:00 UTC 2001
TGFbeta and PTHrP control chondrocyte proliferation by activating cyclin D1 expression.
Molecular biology of the cell
Beier F,Ali Z,Mok D,Taylor AC,Leask T,Albanese C,Pestell RG,LuValle P
MA1-24750 was used in western blot to study the role of cyclin D1 expression in the control of chondrocyte proliferation by TGFbeta and PTHrP
Sat Dec 01 00:00:00 UTC 2001
Effects of arsenite on p53, p21 and cyclin D expression in normal human fibroblasts -- a possible mechanism for arsenite's comutagenicity.
Mutation research
Vogt BL,Rossman TG
MA1-24750 was used in western blot to study the effect of arsenite on p53, p21 and cyclin D expression by human fibroblasts and the mechanistic significance for the comutagenic activity of arsenite
Sun Jul 01 00:00:00 UTC 2001
Cyclin D1 overexpression is a critical event in gallbladder carcinogenesis and independently predicts decreased survival for patients with gallbladder carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research
Hui AM,Li X,Shi YZ,Takayama T,Torzilli G,Makuuchi M
MA1-24750 was used in immunohistochemistry to study the role of the cyclin D1 overexpression in gallbladder carcinogenesis and prognosis
Wed Nov 01 00:00:00 UTC 2000
Abnormal expression of cell cycle regulatory proteins in ductal and lobular carcinomas of the breast.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Geradts J,Ingram CD
MA1-24750 was used in immunohistochemistry to investigate the expression of cell cycle regulatory proteins in breast cancers
Fri Sep 01 00:00:00 UTC 2000
Differential regulation of p27(Kip1) expression by mitogenic and hypertrophic factors: Involvement of transcriptional and posttranscriptional mechanisms.
The Journal of cell biology
Servant MJ,Coulombe P,Turgeon B,Meloche S
MA1-24750 was used in Western Blot to examine the downstream effects of platelet-derived growth factor-BB and Angiotensin II on regulators of the cell cycle machinery in rat aortic smooth muscle cells.
Mon Feb 07 00:00:00 UTC 2000
Primary nodal marginal zone B-cell lymphoma arising from more than one clonal neoplastic population.
Archives of pathology & laboratory medicine
Finch CN,Nichols M,Shrimpton A,Liu D,Hutchison RE
MA1-24750 was used in immunohistochemistry to study the clonality and originatino of primary nodal marginal zone B-cell lymphoma
Fri Dec 01 00:00:00 UTC 2000
v-Jun overrides the mitogen dependence of S-phase entry by deregulating retinoblastoma protein phosphorylation and E2F-pocket protein interactions as a consequence of enhanced cyclin E-cdk2 catalytic activity.
Molecular and cellular biology
Clark W,Black EJ,MacLaren A,Kruse U,LaThangue N,Vogt PK,Gillespie DA
MA1-24750 was used in immunoprecipitation to study the mechanism by which v-Jun promotes S-phase entry in the absence of mitogens
Sat Apr 01 00:00:00 UTC 2000
Cyclin-D1 expression in node-positive (N+) and node-negative (N-) infiltrating human mammary carcinomas.
International journal of cancer
Collecchi P,Passoni A,Rocchetta M,Gnesi E,Baldini E,Bevilacqua G
MA1-24750 was used in immunohistochemistry to study the expression and significance of cyclin D1 in node positive and node negative infiltrating human mammary carcinoma
Tue Apr 20 00:00:00 UTC 1999
Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity.
Molecular and cellular biology
Tsutsui T,Hesabi B,Moons DS,Pandolfi PP,Hansel KS,Koff A,Kiyokawa H
MA1-24750 was used in western blot to study the role of CDK4 in cell cycle regulation using targeted knockdown
Fri Oct 01 00:00:00 UTC 1999
Progesterone inhibits estrogen-induced cyclin D1 and cdk4 nuclear translocation, cyclin E- and cyclin A-cdk2 kinase activation, and cell proliferation in uterine epithelial cells in mice.
Molecular and cellular biology
Tong W,Pollard JW
MA1-24750 was used in western blot to study the molecular mechanisms underlying the effects of female sex hormones on the proliferation of murine uterine epithelial cells
Mon Mar 01 00:00:00 UTC 1999
Inhibition of basal and mitogen-stimulated pancreatic cancer cell growth by cyclin D1 antisense is associated with loss of tumorigenicity and potentiation of cytotoxicity to cisplatinum.
The Journal of clinical investigation
Kornmann M,Arber N,Korc M
MA1-24750 was used in western blot to study the effect of cyclin D1 knockdown on the tumorigenicity and cisplantin-sensitivity of PANC-1 human pancreatic cancer cells
Thu Jan 15 00:00:00 UTC 1998
Ligand-independent recruitment of steroid receptor coactivators to estrogen receptor by cyclin D1.
Genes & development
Zwijsen RM,Buckle RS,Hijmans EM,Loomans CJ,Bernards R
MA1-24750 was used in western blot to study the role of cyclin D1 in ligand-independent recruitment of steroid receptor coactivators to estrogen receptors
Sun Nov 15 00:00:00 UTC 1998
Anchorage-independent transcription of the cyclin A gene induced by the E7 oncoprotein of human papillomavirus type 16.
Journal of virology
Schulze A,Mannhardt B,Zerfass-Thome K,Zwerschke W,Jansen-Dürr P
MA1-24750 was used in western blot to study the mechanisms by which the HPV-16 E7 protein induces anchorage-independent cell growth
Sun Mar 01 00:00:00 UTC 1998
A K-ras oncogene increases resistance to sulindac-induced apoptosis in rat enterocytes.
Gastroenterology
Arber N,Han EK,Sgambato A,Piazza GA,Delohery TM,Begemann M,Weghorst CM,Kim NH,Pamukcu R,Ahnen DJ,Reed JC,Weinstein IB,Holt PR
MA1-24750 was used in immunoprecipitation to study the effect of c-K-ras mutations on the response to the chemopreventive agent sulindac in rat enterocytes
Mon Dec 01 00:00:00 UTC 1997
The subcellular locations of p15(Ink4b) and p27(Kip1) coordinate their inhibitory interactions with cdk4 and cdk2.
Genes & development
Reynisdóttir I,Massagué J
MA1-24750 was used in immunocytochemistry to study the role of p15(Ink4b) and p27(Kip1) subcellular localization in the coordinate regulation of cdk2 and cdk4
Sat Feb 15 00:00:00 UTC 1997
Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4.
Molecular and cellular biology
Neuman E,Ladha MH,Lin N,Upton TM,Miller SJ,DiRenzo J,Pestell RG,Hinds PW,Dowdy SF,Brown M,Ewen ME
MA1-24750 was used in western blot to study the cdk4-independent stimulation of estrogen receptor transcriptional activity by cyclin D1
Mon Sep 01 00:00:00 UTC 1997
