Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
Cyclophilin 40 Monoclonal Antibody (5A6)
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
FIGURE: 1 / 9
Cyclophilin 40 Antibody (MA5-49223) in ICC/IF
Immunocytochemistry analysis of Cyclophilin 40 in A431 cells. Enzyme antigen retrieval was performed using IHC enzyme antigen retrieval reagent for 15 mins. The cells were blocked with 10% goat serum. Samples were then incubated in Cyclophilin 40 Monoclonal antibody (Product # MA5-49223) using a dilution of 5 μg/mL. DyLight®488 Conjugated Goat Anti-Mouse IgG was used as secondary antibody at 1:100 dilution ... View More
Product Details
MA5-49223
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
5A6
Immunogen
E. coli-derived human PPID recombinant protein (Position: N306-A370).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_3074881
Product Specific Information
Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Positive Control - WB: HL-60 whole cell, K562 whole cell, THP-1 whole cell, COS-7 whole cell, rat brain tissue, rat spleen tissue, rat liver tissue, mouse brain tissue, mouse liver tissue, HEPA1-6 whole cell. IHC: human intestinal cancer tissue, human intestinal cancer tissue, human mammary cancer tissue, mouse small intestine tissue, mouse small intestine tissue. ICC/IF: A431 cell. Flow: A431 cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
This gene encodes a H1 histone binding protein that is involved in transporting histones into the nucleus of dividing cells. Multiple isoforms are encoded by transcript variants of this gene. The somatic form is expressed in all mitotic cells, is localized to the nucleus, and is coupled to the cell cycle. The testicular form is expressed in embryonic tissues, tumor cells, and the testis. In male germ cells, this protein is localized to the cytoplasm of primary spermatocytes, the nucleus of spermatids, and the periacrosomal region of mature spermatozoa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: 40 kDa peptidyl-prolyl cis-trans isomerase; 40 kDa peptidyl-prolyl cis-trans isomerase D; cyclophilin 40; Cyclophilin D; Cyclophilin-40; Cyclophilin-related protein; Cyp 40; Cyp D; CYP-40; CYP-S1; cytoplasmic cyclophilin D; EC 5.2.1.8; MGC33096; Peptidyl-prolyl cis-trans isomerase D; PPIase; PPIase D; rotamase; Rotamase D; S-cyclophilin; SCYLP; testicular tissue protein Li 147
Gene Aliases: 4930564J03Rik; CYP-40; CYP40; CYPD; PPID; Ppidl; Ppif
UniProt ID: (Human) Q08752, (Mouse) Q9CR16, (Rat) Q6DGG0
Entrez Gene ID: (Human) 5481, (Mouse) 67738, (Rat) 361967
negative regulation of transcription from RNA polymerase II promoter
protein peptidyl-prolyl isomerization
protein folding
protein complex assembly
transport
apoptotic process
protein transport
lipid particle organization
regulation of apoptotic process
positive regulation of apoptotic process
positive regulation of viral genome replication
positive regulation of protein secretion
chaperone-mediated protein folding
cellular response to UV-A
response to oxidative stress
negative regulation of apoptotic process
regulation of mitochondrial membrane potential
viral release from host cell
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support