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Invitrogen
Cyclophilin F Polyclonal Antibody
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Product Details
PA5-98077
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Peptidyl-prolyl cis-trans isomerase F, mitochondrial protein (30-207AA)
Conjugate
Form
Liquid
Concentration
0.82 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Wet ice
RRID
AB_2812691
Target Information
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cyclophilin 3; Cyclophilin D; Cyclophilin F; CyP-D; CyP-M; Mitochondrial cyclophilin; mitochondrial peptidyl-prolyl cis-trans isomerase; Peptidyl-prolyl cis-trans isomerase F; Peptidyl-prolyl cis-trans isomerase F, mitochondrial; peptidyl-prolyl cis-trans isomerase, mitochondrial; PPIase F; Rotamase F
Gene Aliases: Cyp-D; CyP-M; CYP3; CypD; PPIF
UniProt ID: (Human) P30405
Entrez Gene ID: (Human) 10105
protein peptidyl-prolyl isomerization
response to ischemia
protein folding
apoptotic mitochondrial changes
regulation of proton-transporting ATPase activity, rotational mechanism
regulation of necrotic cell death
negative regulation of ATPase activity
negative regulation of apoptotic process
regulation of mitochondrial membrane permeability
necroptotic process
cellular response to hydrogen peroxide
cellular response to arsenic-containing substance
cellular response to calcium ion
positive regulation of release of cytochrome c from mitochondria
negative regulation of release of cytochrome c from mitochondria
negative regulation of oxidative phosphorylation
regulation of mitochondrial membrane permeability involved in programmed necrotic cell death
negative regulation of oxidative phosphorylation uncoupler activity
negative regulation of intrinsic apoptotic signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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