Invitrogen

Cytochrome C1 Polyclonal Antibody

Cytochrome C1 Antibody in Immunocytochemistry (ICC/IF)

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Cytochrome C1 Antibody (PA5-51550) in ICC/IF

Immunofluorecent analysis of Cytochrome C1 in human cell line U-251 MG using Cytochrome C1 Polyclonal Antibody (Product # PA5-51550). Staining shows localization to mitochondria.

Cytochrome C1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Cytochrome C1 Antibody in Western Blot (WB)

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Product Details

PA5-51550

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human Cytochrome C1. Recombinant protein control fragment (Product #RP-99401).

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2640351

Product Specific Information

Immunogen sequence: NSEAARAANN GALPPDLSYI VRARHGGEDY VFSLLTGYCE PPTGVSLREG LYFNPYFPGQ AIAMAPPIYT DVLEFDDGTP ATMSQIAKDV CTFLRWASEP EHDHRKRMGL KMLMMMALLV PLVYTIKRHK WSVLKSRKLA YR

Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.

Target Information

This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Effects of epigenetic pathway inhibitors on corticotroph tumour AtT20 cells.

Endocrine-related cancer

Lines KE,Filippakopoulos P,Stevenson M,Müller S,Lockstone HE,Wright B,Knapp S,Buck D,Bountra C,Thakker RV

PA5-51550 was used in Western Blot to conclude that JQ1 treatment has anti-proliferative and pro-apoptotic effects on AtT20 cells and reduces ACTH secretion, thereby indicating that BET inhibition may provide a novel approach for treatment of corticotrophinomas.

Sun Mar 01 00:00:00 UTC 2020

Effects of epigenetic pathway inhibitors on corticotroph tumour AtT20 cells.

Endocrine-related cancer

Lines KE,Filippakopoulos P,Stevenson M,Müller S,Lockstone HE,Wright B,Knapp S,Buck D,Bountra C,Thakker RV

Sun Mar 01 00:00:00 UTC 2020

Protective Effects of Foam Rolling against Inflammation and Notexin Induced Muscle Damage in Rats.

International journal of medical sciences

Pablos A,Ceca D,Jorda A,Rivera P,Colmena C,Elvira L,Martínez-Arnau FM,Valles SL

PA5-51550 was used in Western Blot to conclude that applying foam rolling after damage has benefits such as an increase in anti-inflammatory proteins and a reduction of pro-inflammatory proteins, resulting in muscle recovery and better performance.

Mon Oct 05 00:00:00 UTC 2020

Protective Effects of Foam Rolling against Inflammation and Notexin Induced Muscle Damage in Rats.

International journal of medical sciences

Pablos A,Ceca D,Jorda A,Rivera P,Colmena C,Elvira L,Martínez-Arnau FM,Valles SL

Mon Oct 05 00:00:00 UTC 2020

Bioinformatics

Protein Aliases: Complex III subunit 4; Complex III subunit IV; Cytochrome b-c1 complex subunit 4; Cytochrome c-1; Cytochrome c1, heme protein, mitochondrial; Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit

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Gene Aliases: 2610002H19Rik; AA408921; CYC1; MC3DN6; UQCR4

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UniProt ID: (Human) P08574, (Mouse) Q9D0M3

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Entrez Gene ID: (Human) 1537, (Rat) 300047, (Mouse) 66445

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Function(s)

heme binding electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity metal ion binding molecular_function iron ion binding electron carrier activity protein binding

Process(es)

response to glucagon mitochondrial electron transport, ubiquinol to cytochrome c transport oxidation-reduction process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Cytochrome C1 Polyclonal Antibody

Cytochrome C1 Antibody (PA5-51550) in ICC/IF

Product Details

PA5-51550

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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