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Bioss
Cytochrome P450 4A Polyclonal Antibody
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Product Details
BS-5054R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human Cytochrome P450 4A.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates medium-chain fatty acids such as laurate and myristate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 20-HETE synthase; 20-hydroxyeicosatetraenoic acid synthase; alkane-1 monooxygenase; cyp4a10; cyp4a14; CYP4AII; CYPIVA10; CYPIVA11; CYPIVA12; CYPIVA14; CYPIVA2; CYPIVA22; Cytochrome P-450 K-2; Cytochrome P-450HK-omega; Cytochrome P450 4A10; Cytochrome P450 4A11; Cytochrome P450 4A12A; Cytochrome P450 4A14; Cytochrome P450 4A2; Cytochrome P450 4A22; cytochrome P450 4A22K; cytochrome P450 4A3; Cytochrome P450 K-5; cytochrome P450, 4A1; cytochrome P450, 4a10; cytochrome P450, 4a14; cytochrome P450, family 4, subfamily a, polypeptide 10; cytochrome P450, family 4, subfamily A, polypeptide 11; cytochrome P450, family 4, subfamily a, polypeptide 12; cytochrome P450, family 4, subfamily a, polypeptide 14; cytochrome P450, family 4, subfamily A, polypeptide 22; cytochrome P450, IVA1; cytochrome P450, subfamily 4A, polypeptide 11; cytochrome P450, subfamily IVA, polypeptide 11; Cytochrome P450-LA-omega 1; Cytochrome P450-LA-omega 2; Cytochrome P450-LA-omega 3; Cytochrome P450HL-omega; Cytochrome P452; Fatty acid omega-hydroxylase; Lauric acid hydroxylase; Lauric acid omega-hydroxylase; lauric acid omega-hydroxylase 3; Long-chain fatty acid omega-monooxygenase; P-450 IV4AII; P-450 K-2; P450 K-5; P450-LA-omega 2; P450-LA-omega 3; P450HL-omega
Gene Aliases: AI314743; AI647584; BC025936; CP4Y; Cyp4a; Cyp4a-1; Cyp4a-10; Cyp4a-2; Cyp4a-3; Cyp4a1; Cyp4a10; CYP4A11; Cyp4a12; Cyp4a12a; Cyp4a14; CYP4A2; CYP4A22; Cyp4a3; CYP4AII; CYPIVA10; CYPIVA3; D4Rp1; RP1
UniProt ID: (Human) Q02928, (Human) Q5TCH4, (Rat) P08516, (Mouse) O88833, (Mouse) Q91WL5, (Mouse) O35728, (Rat) P20816, (Rat) P20817
Entrez Gene ID: (Human) 1579, (Human) 284541, (Rat) 50549, (Mouse) 13117, (Mouse) 277753, (Mouse) 13119, (Rat) 24306, (Rat) 298423
monooxygenase activity
iron ion binding
arachidonic acid epoxygenase activity
alkane 1-monooxygenase activity
oxygen binding
heme binding
leukotriene-B4 20-monooxygenase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
arachidonic acid monooxygenase activity
arachidonic acid omega-hydroxylase activity
oxidoreductase activity
metal ion binding
aromatase activity
fatty acid binding
arachidonic acid binding
arachidonic acid 11,12-epoxygenase activity
kidney development
response to hormone
arachidonic acid metabolic process
response to drug
linoleic acid metabolic process
icosanoid biosynthetic process
lauric acid metabolic process
oxidation-reduction process
long-chain fatty acid metabolic process
placenta development
renal water homeostasis
pressure natriuresis
leukotriene metabolic process
epoxygenase P450 pathway
positive regulation of icosanoid secretion
leukotriene B4 catabolic process
sodium ion homeostasis
fatty acid metabolic process
omega-hydroxylase P450 pathway
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