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Invitrogen
Cytohesin 1 Monoclonal Antibody (2E11)
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FIGURE: 1 / 9
Cytohesin 1 Antibody (MA1-060) in ICC/IF
Immunofluorescence analysis of Cytohesin 1 was done on 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with Cytohesin 1 (2E11) Mouse Monoclonal Antibody (Product # MA1-060) at 2 µg/mL in 0.1% BSA and incubated for 3 hours at ro... View More
Product Details
MA1-060
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2E11
Immunogen
Purified, His-tagged cytohesin-1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
PEG precipitation
Storage buffer
PBS with 1mg/mL BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2230263
Product Specific Information
MA1-060 detects cytohesin-1 from human and mouse cells as well as recombinant human protein.
MA1-060 has been successfully used in Western blot and IF procedures. By Western blot, this antibody detects an ~48 kDa protein representing cytohesin-1.
The MA1-060 immunogen is purified, His-tagged cytohesin-1.
Target Information
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domains, and thus represents a receptor-type PTP. The similar gene predominately expressed in mouse brain was found to associate with, and thus regulate the activity and cellular localization of MAP kinases. The rat counterpart of this gene was reported to be regulated by the nerve growth factor, which suggested the function of this gene in neuronal growth and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CLM1; cytoadhesin 1; Cytohesin-1; FLJ34050; FLJ41900; homolog of secretory protein SEC7; mSec7-1; PH, SEC7 and coiled-coil domain-containing protein 1; pleckstrin homology, Sec7 and coiled-coil domains 1; SEC7 homolog A; SEC7 homolog B2-1
Gene Aliases: B2-1; CLM1; CTH-1; CYTH1; CYTIP; CYTOHESIN-1; D17S811E; mKIAA4240; PSCD1; SEC7
UniProt ID: (Human) Q15438, (Mouse) Q9QX11
Entrez Gene ID: (Human) 9267, (Mouse) 19157
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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