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          • Primary Antibodies ›
          • Cytokeratin 1 Antibodies

          NeoBiotechnologies

          Cytokeratin 1 (Suprabasal Keratinocyte Marker) Monoclonal Antibody (KRT1/1840)

          View all (20) Cytokeratin 1 antibodies

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          Cite Cytokeratin 1 (Suprabasal Keratinocyte Marker) Monoclonal Antibody (KRT1/1840)

          • Antibody Testing Data (3)
          Cytokeratin 1 (Suprabasal Keratinocyte Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          Cytokeratin 1 (Suprabasal Keratinocyte Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          Cytokeratin 1 (Suprabasal Keratinocyte Marker) Antibody (3848-MSM3-P0) in IHC (P)

          Formalin-fixed, paraffin-embedded human Cervical Carcinoma stained with Cytokeratin 1 Mouse Monoclonal Antibody (KRT1/1840). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Cytokeratin 1 (Suprabasal Keratinocyte Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Cytokeratin 1 (Suprabasal Keratinocyte Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Cytokeratin 1 (Suprabasal Keratinocyte Marker) Antibody in SDS-PAGE (SDS-PAGE)

          Product Details

          3848-MSM3-P0

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          Assay-dependent
          -

          Immunohistochemistry (PFA fixed) (IHC (PFA))

          2-4 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human, Rat

          Host/Isotype

          Mouse / IgG2a, kappa

          Class

          Monoclonal

          Type

          Antibody

          Clone

          KRT1/1840

          Immunogen

          Recombinant full-length human KRT1 protein
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          200 µg/mL

          Purification

          Protein A/G

          Storage buffer

          PBS, pH 7.4, with 0.05% BSA

          Contains

          0.05% sodium azide

          Storage conditions

          4°C, do not freeze

          Shipping conditions

          Wet ice

          Target Information

          Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately40 kDa and approximately68 kDa and isoelectric pH between 4. 9 - 7. 8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: 67 kDa cytokeratin; CK-1; cytokeratin 1; Cytokeratin-1; epidermolytic hyperkeratosis 1; Hair alpha protein; K1; keratin 1, type II; Keratin, type II cytoskeletal 1; Keratin-1; krt1 {ECO:0000250|UniProtKB:P04264}; type II keratin Kb1; Type-II keratin Kb1

          View more View less

          Gene Aliases: CK1; EHK; EHK1; EPPK; K1; Kb1; KRT1; KRT1A; KRTA; NEPPK

          View more View less

          UniProt ID: (Human) P04264, (Rat) Q6IMF3

          View more View less

          Entrez Gene ID: (Human) 3848, (Rat) 300250

          View more View less

          Function(s)
          receptor activity structural molecule activity protein binding carbohydrate binding molecular_function
          Process(es)
          complement activation, lectin pathway retina homeostasis response to oxidative stress fibrinolysis regulation of angiogenesis negative regulation of inflammatory response establishment of skin barrier biological_process
          It has to be done as per old AB suggested Products section.
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