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          • Primary Antibodies ›
          • Cytokeratin 10/14/17/19/42 Antibodies

          Bioss

          Cytokeratin 10+14+17+19+42 Polyclonal Antibody

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          Datasheet
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          Cite Cytokeratin 10+14+17+19+42 Polyclonal Antibody

          • Antibody Testing Data (1)
          Cytokeratin 10+14+17+19+42 Antibody in Western Blot (WB)
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          Cytokeratin 10+14+17+19+42 Antibody in Western Blot (WB)
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          FIGURE: 1 / 1

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          Cytokeratin 10+14+17+19+42 Antibody (BS-11185R) in WB

          Urinary bladder lysates probed with Cytokeratin 10+14+17+19+42 Polyclonal Antibody, Unconjugated (bs-11185R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37°C. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Cytokeratin 10+14+17+19+42 Antibody in Western Blot (WB)

          Product Details

          BS-11185R

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000
          -

          ELISA (ELISA)

          1:500-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          KLH conjugated synthetic peptide derived from human Cytokeratin 19.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein A

          Storage buffer

          PBS with 1% BSA, 50% glycerol

          Contains

          0.09% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.This gene encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. [provided by RefSeq, Aug 2008].

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: 39.1; 40-kDa keratin intermediate filament; 56 kDa cytokeratin; CK-10; CK-14; CK-17; CK-19; cytokeratin 10; cytokeratin 14; cytokeratin 19; Cytokeratin-10; Cytokeratin-14; Cytokeratin-17; Cytokeratin-19; epidermal keratin 10; epidermolysis bullosa simplex, Dowling-Meara, Koebner; intermediate filament protein; K10; K14; K17; K19; keratin 10, type I; keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner); keratin 14, type I; keratin 17, type I; keratin 19, type I; keratin complex 1, acidic, gene 10; keratin complex 1, acidic, gene 14; keratin complex 1, acidic, gene 17; keratin complex 1, acidic, gene 19; Keratin, type I cytoskeletal 10; Keratin, type I cytoskeletal 14; Keratin, type I cytoskeletal 17; Keratin, type I cytoskeletal 19; Keratin, type I cytoskeletal 59 kDa; keratin, type I, 40-kd; Keratin-10; Keratin-14; Keratin-17; Keratin-19; krt10 {ECO:0000250|UniProtKB:P13645}; krt17 {ECO:0000250|UniProtKB:Q04695}; suprabasal cytokeratin 10; type I keratin KA10; Type I keratin Ka14; Type I keratin Ka17; Type I keratin Ka19

          View more View less

          Gene Aliases: 39.1; AI626930; AI663979; BCIE; BIE; CK-17; CK10; CK14; CK19; D130054E02Rik; EBS3; EBS4; EHK; EndoC; K10; K14; K17; K19; K1C1; K1CS; Ka10; Ka14; Ka17; Ka19; KPP; Krt-1.10; Krt-1.14; Krt-1.19; Krt1-10; Krt1-14; Krt1-17; Krt1-19; KRT10; KRT14; KRT17; KRT19; NFJ; PC; PC2; PCHC1

          View more View less

          UniProt ID: (Human) P13645, (Human) P02533, (Human) Q04695, (Human) P08727, (Mouse) P02535, (Mouse) Q61781, (Rat) Q6IFV1, (Mouse) Q9QWL7, (Rat) Q6IFU8, (Mouse) P19001, (Rat) Q63279

          View more View less

          Entrez Gene ID: (Human) 3858, (Human) 3861, (Human) 3872, (Human) 3880, (Mouse) 16661, (Rat) 450225, (Mouse) 16664, (Rat) 287701, (Mouse) 16667, (Rat) 287702, (Mouse) 16669, (Rat) 360626

          View more View less

          Function(s)
          structural constituent of epidermis structural constituent of cytoskeleton protein binding keratin filament binding MHC class II receptor activity MHC class II protein binding structural constituent of muscle protein complex binding structural molecule activity molecular_function
          Process(es)
          morphogenesis of an epithelium signal transduction positive regulation of cell growth hair follicle morphogenesis keratinization intermediate filament organization positive regulation of translation positive regulation of hair follicle development Notch signaling pathway viral process response to estrogen sarcomere organization cell differentiation involved in embryonic placenta development aging epithelial cell differentiation hair cycle intermediate filament bundle assembly cellular response to calcium ion biological_process keratinocyte differentiation epidermis development response to zinc ion response to ionizing radiation hemidesmosome assembly intermediate filament-based process
          It has to be done as per old AB suggested Products section.
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