Product References
Stress keratin 17 and estrogen support viral persistence and modulate the immune environment during cervicovaginal murine papillomavirus infection.
Proceedings of the National Academy of Sciences of the United States of America
Wang W,Spurgeon ME,Pope A,McGregor S,Ward-Shaw E,Gronski E,Lambert PF
PA5-16722 was used in Immunohistochemistry to suggest that estrogen and K17 act at multiple stages of papillomavirus-induced disease at least in part via immunomodulatory mechanisms.
Tue Mar 21 00:00:00 UTC 2023
EZH2 and Endometrial Cancer Development: Insights from a Mouse Model.
Cells
Fang X,Ni N,Wang X,Tian Y,Ivanov I,Rijnkels M,Bayless KJ,Lydon JP,Li Q
PA5-16722 was used in Immunohistochemistry to show reduced tumor burden in Ptend/d; Ezh2d/d mice compared with that of Ptend/d mice during early carcinogenesis.
Mon Mar 07 00:00:00 UTC 2022
EZH2 and Endometrial Cancer Development: Insights from a Mouse Model.
Cells
Fang X,Ni N,Wang X,Tian Y,Ivanov I,Rijnkels M,Bayless KJ,Lydon JP,Li Q
PA5-16722 was used in Immunohistochemistry to show reduced tumor burden in Ptend/d; Ezh2d/d mice compared with that of Ptend/d mice during early carcinogenesis.
Mon Mar 07 00:00:00 UTC 2022
Role of EZH2 in Uterine Gland Development.
International journal of molecular sciences
Ni N,Jalufka FL,Fang X,McCreedy DA,Li Q
PA5-16722 was used in Immunohistochemistry-immunofluorescence to identify an unrecognized role of EZH2 in uterine gland development, a postnatal event critical for pregnancy success and female fertility.
Sat Dec 10 00:00:00 UTC 2022
SARS-CoV-2 Infection Dysregulates Cilia and Basal Cell Homeostasis in the Respiratory Epithelium of Hamsters.
International journal of molecular sciences
Schreiner T,Allnoch L,Beythien G,Marek K,Becker K,Schaudien D,Stanelle-Bertram S,Schaumburg B,Mounogou Kouassi N,Beck S,Zickler M,Gabriel G,Baumgärtner W,Armando F,Ciurkiewicz M
PA5-16722 was used in Immunohistochemistry to provide new insights into SARS-CoV-2 pathogenesis and expands our understanding of virally induced damage to defense mechanisms in the conducting airways.
Wed May 04 00:00:00 UTC 2022
Breast tumor IGF1R regulates cell adhesion and metastasis: alignment of mouse single cell and human breast cancer transcriptomics.
Frontiers in oncology
Obr AE,Bulatowicz JJ,Chang YJ,Ciliento V,Lemenze A,Maingrette K,Shang Q,Gallagher EJ,LeRoith D,Wood TL
PA5-16722 was used in Immunocytochemistry to find that reduced IGF1R signaling in tumor epithelial cells dysregulates cadherin expression resulting in reduced cell adhesion.
Fri Feb 24 00:00:00 UTC 2023
Functional similarity between TGF-beta type 2 and type 1 receptors in the female reproductive tract.
Scientific reports
Ni N,Fang X,Li Q
PA5-16722 was used in Immunohistochemistry to reveal the functional similarity between TGFBR2 and TGFBR1 in maintaining the structural integrity of the female reproductive tract.
Thu Apr 29 00:00:00 UTC 2021
Functional similarity between TGF-beta type 2 and type 1 receptors in the female reproductive tract.
Scientific reports
Ni N,Fang X,Li Q
PA5-16722 was used in Immunohistochemistry to reveal the functional similarity between TGFBR2 and TGFBR1 in maintaining the structural integrity of the female reproductive tract.
Thu Apr 29 00:00:00 UTC 2021
Stress keratin 17 enhances papillomavirus infection-induced disease by downregulating T cell recruitment.
PLoS pathogens
Wang W,Uberoi A,Spurgeon M,Gronski E,Majerciak V,Lobanov A,Hayes M,Loke A,Zheng ZM,Lambert PF
Published figure using Cytokeratin 14 polyclonal antibody (Product # PA5-16722) in Flow Cytometry
Wed Jan 01 00:00:00 UTC 2020
Enhancer of Zeste 2 Polycomb Repressive Complex 2 Subunit Is Required for Uterine Epithelial Integrity.
The American journal of pathology
Fang X,Ni N,Lydon JP,Ivanov I,Bayless KJ,Rijnkels M,Li Q
PA5-16722 was used in Immunohistochemistry to propose the Ezh2 conditional knockout mouse model may be useful to explore mechanisms that regulate endometrial homeostasis and uterine function.
Sat Jun 01 00:00:00 UTC 2019
Microenvironment-Induced Non-sporadic Expression of the AXL and cKIT Receptors Are Related to Epithelial Plasticity and Drug Resistance.
Frontiers in cell and developmental biology
Jokela TA,Engelsen AST,Rybicka A,Pelissier Vatter FA,Garbe JC,Miyano M,Tiron C,Ferariu D,Akslen LA,Stampfer MR,Lorens JB,LaBarge MA
PA5-16722 was used in Immunohistochemistry-immunofluorescence to examine the mechanisms causing the non-sporadic expression of proteins related to epithelial plasticity and drug resistance in the tumour microenvironment.
Thu Mar 14 00:00:00 UTC 2024
The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα.
Nature
Britschgi A,Duss S,Kim S,Couto JP,Brinkhaus H,Koren S,De Silva D,Mertz KD,Kaup D,Varga Z,Voshol H,Vissieres A,Leroy C,Roloff T,Stadler MB,Scheel CH,Miraglia LJ,Orth AP,Bonamy GM,Reddy VA,Bentires-Alj M
PA516722 was used in immunocytochemistry and western blot to define the interaction between LATS1/2 and the estrogen receptor signaling in breast cancer initiation.
Thu Jan 26 00:00:00 UTC 2017
Hyaluronan Rich Microenvironment in the Limbal Stem Cell Niche Regulates Limbal Stem Cell Differentiation.
Investigative ophthalmology & visual science
Gesteira TF,Sun M,Coulson-Thomas YM,Yamaguchi Y,Yeh LK,Hascall V,Coulson-Thomas VJ
Published figure using Cytokeratin 14 polyclonal antibody (Product # PA5-16722) in Immunofluorescence
Fri Sep 01 00:00:00 UTC 2017
Constitutively activated PI3K accelerates tumor initiation and modifies histopathology of breast cancer.
Oncogenesis
Sheen MR,Marotti JD,Allegrezza MJ,Rutkowski M,Conejo-Garcia JR,Fiering S
PA516722 was used in immunohistochemistry - paraffin section to determine if PIK3CA mutations contribute to tumor initiation
Mon Oct 31 00:00:00 UTC 2016
PIK3CA(H1047R) induces multipotency and multi-lineage mammary tumours.
Nature
Koren S,Reavie L,Couto JP,De Silva D,Stadler MB,Roloff T,Britschgi A,Eichlisberger T,Kohler H,Aina O,Cardiff RD,Bentires-Alj M
PA5-16722 was used in western blot to elucidate the potential of PIK3CA to induce multipotency during tumorigenesis in the mammary gland.
Thu Sep 03 00:00:00 UTC 2015
Programmed synthesis of three-dimensional tissues.
Nature methods
Todhunter ME,Jee NY,Hughes AJ,Coyle MC,Cerchiari A,Farlow J,Garbe JC,LaBarge MA,Desai TA,Gartner ZJ
PA5-16722 was used in immunocytochemistry to study three-dimensional tissues by programmed synthesis
Thu Oct 01 00:00:00 UTC 2015
Aspirin blocks growth of breast tumor cells and tumor-initiating cells and induces reprogramming factors of mesenchymal to epithelial transition.
Laboratory investigation; a journal of technical methods and pathology
Maity G,De A,Das A,Banerjee S,Sarkar S,Banerjee SK
PA5-16722 was used in western blot to evaluate the effect of aspirin in mesenchymal to epithelial transition
Wed Jul 01 00:00:00 UTC 2015
Modelling breast cancer requires identification and correction of a critical cell lineage-dependent transduction bias.
Nature communications
Hines WC,Yaswen P,Bissell MJ
PA5-16722 was used in immunocytochemistry to study and identify critical cell lineage-dependent transduction bias to model breast cancer properly
Tue Apr 21 00:00:00 UTC 2015
Label-retaining, quiescent globose basal cells are found in the olfactory epithelium.
The Journal of comparative neurology
Jang W,Chen X,Flis D,Harris M,Schwob JE
PA5-16722 was used in immunohistochemistry to study the presence in olfactory epithelium of quiescent globose basal cells that retain thymidine analogue labels
Sat Mar 01 00:00:00 UTC 2014
Afadin requirement for cytokine expressions in keratinocytes during chemically induced inflammation in mice.
Genes to cells : devoted to molecular & cellular mechanisms
Yoshida T,Iwata T,Takai Y,Birchmeier W,Yamato M,Okano T
PA5-16722 was used in immunohistochemistry - paraffin section to investigate the role of afadin in epithelial tissue development using epithelium-specific afadin-deficient mice
Sat Nov 01 00:00:00 UTC 2014
Solitary tumours associated with Jaagsiekte retrovirus in sheep are heterogeneous and contain cells expressing markers identifying progenitor cells in lung repair.
Journal of comparative pathology
De las Heras M,de Martino A,Borobia M,Ortín A,Álvarez R,Borderías L,Giménez-Más JA
PA5-16722 was used in immunohistochemistry to study the heterogeneity and the presence of lung repair progenitor cells in Jaagsiekte retrovirus-associated solitary tumors in sheep
Tue Nov 18 00:00:00 UTC 2014
Global expression profiling of globose basal cells and neurogenic progression within the olfactory epithelium.
The Journal of comparative neurology
Krolewski RC,Packard A,Schwob JE
PA5-16722 was used in immunohistochemistry to profile the expression pattern of globose basal cells within the olfactory epithelium
Fri Mar 01 00:00:00 UTC 2013
A small molecule inhibitor of SRC family kinases promotes simple epithelial differentiation of human pluripotent stem cells.
PloS one
Lian X,Selekman J,Bao X,Hsiao C,Zhu K,Palecek SP
PA5-16722 was used in flow cytometry and immunocytochemistry to describe conditions that promote development of hPSC-derived simple epithelial cells
Tue Sep 17 00:00:00 UTC 2013
Ascl1 (Mash1) knockout perturbs differentiation of nonneuronal cells in olfactory epithelium.
PloS one
Krolewski RC,Packard A,Jang W,Wildner H,Schwob JE
PA5-16722 was used in immunohistochemistry to study the abnormal differentiation of non-neuronal cells in the olfactory epithelium of ASCL1 knockout mice
Mon Jun 17 00:00:00 UTC 2013
Py2T murine breast cancer cells, a versatile model of TGFβ-induced EMT in vitro and in vivo.
PloS one
Waldmeier L,Meyer-Schaller N,Diepenbruck M,Christofori G
PA5-16722 was used in immunocytochemistry to develop a novel cellular model of epithelial-to-mesenchymal transition based on the use of mouse Py2T breast cancer cells
Wed Apr 24 00:00:00 UTC 2013
Luminal expression of PIK3CA mutant H1047R in the mammary gland induces heterogeneous tumors.
Cancer research
Meyer DS,Brinkhaus H,Müller U,Müller M,Cardiff RD,Bentires-Alj M
PA5-16722 was used in immunohistochemistry to elucidate the contribution of PIK3CA H1047R to breast cancer pathogenesis.
Fri Jul 01 00:00:00 UTC 2011
An immunohistochemical method to study breast cancer cell subpopulations and their growth regulation by hormones in three-dimensional cultures.
Frontiers in endocrinology
Pinto MP,Jacobsen BM,Horwitz KB
PA5-16722 was used in immunocytochemistry and immunohistochemistry - paraffin section to develop a simple and inexpensive method to analyze cell subpopulations in mixed-cell colonies
Thu Aug 23 00:00:00 UTC 2012
An oestrogen-dependent model of breast cancer created by transformation of normal human mammary epithelial cells.
Breast cancer research : BCR
Duss S,André S,Nicoulaz AL,Fiche M,Bonnefoi H,Brisken C,Iggo RD
PA5-16722 was used in immunocytochemistry and immunohistochemistry to develop an estrogen receptor-alpha-positive model of breast cancer using human mammary epithelial cells
Fri Sep 14 00:00:00 UTC 2007
