Proteintech

Cytokeratin 15 Polyclonal Antibody

Cytokeratin 15 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 15

Cytokeratin 15 Antibody (10137-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue slide using (Product # 10137-1-AP) Cytokeratin 15 antibody at dilution of 1:800 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

Cytokeratin 15 Antibody in Western Blot (WB)

Cytokeratin 15 Antibody in Flow Cytometry (Flow)

Cytokeratin 15 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

10137-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 2 publications 2 publications

Immunohistochemistry (IHC)

View 6 publications 6 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 9 publications 9 publications

Flow Cytometry (Flow)

Assay-dependent

Immunoprecipitation (IP)

0.5-4.0 µg

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Cytokeratin 15 Fusion Protein Ag0185 (238-450 aa encoded by BC002641)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.25 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: AYLKKNHEE EMKEFSSQLA GQVNVEMDAA PGVDLTRVLA EMREQYEAMA EKNRRDVEAW FFSKTEELNK EVASNTEMIQ TSKTEITDLR RTMQELEIEL QSQLSMKAGL ENSLAETECR YATQLQQIQG LIGGLEAQLS ELRCEMEAQN QEYKMLLDIK TRLEQEIATY RSLLEGQDAK MAGIGIREAS SGGGGSSSNF HINVEESVDG QVVS (238-450 aa encoded by B C002641)

Target Information

Cytokeratin 15 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region on chromosome 17q21. 2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Distinct bulge stem cell populations maintain the pilosebaceous unit in a β-catenin-dependent manner.

iScience

Han J,Lin K,Choo H,Chen Y,Zhang X,Xu RH,Wang X,Wu Y

Fri Jan 20 00:00:00 UTC 2023

Metformin Promotes Mechanical Stretch-Induced Skin Regeneration by Improving the Proliferative Activity of Skin-Derived Stem Cells.

Frontiers in medicine

Xiong S,Liu W,Song Y,Du J,Wang T,Zhang Y,Huang Z,He Q,Dong C,Yu Z,Ma X

Sat Jul 16 00:00:00 UTC 2022

Metformin Promotes Mechanical Stretch-Induced Skin Regeneration by Improving the Proliferative Activity of Skin-Derived Stem Cells.

Frontiers in medicine

Xiong S,Liu W,Song Y,Du J,Wang T,Zhang Y,Huang Z,He Q,Dong C,Yu Z,Ma X

Sat Jul 16 00:00:00 UTC 2022

A hybrid hydrogel composed of chitin and β-glucan for the effective management of wound healing and scarring.

Biomaterials science

Kang X,Lei J,Yang C,Zhang P,Li X,Zheng S,Li Q,Zhang J

Tue Oct 11 00:00:00 UTC 2022

Curcumin Promotes Primary Oral Wound Healing in a Rat Model.

Journal of medicinal food

Chaushu L,Rahmanov Gavrielov M,Chaushu G,Zar K,Vered M

Thu Apr 01 00:00:00 UTC 2021

Wounding Induces Facultative Opn5-Dependent Circadian Photoreception in the Murine Cornea.

Investigative ophthalmology & visual science

Díaz NM,Lang RA,Van Gelder RN,Buhr ED

Wed Jun 03 00:00:00 UTC 2020

Palatal Wound Healing with Primary Intention in a Rat Model-Histology and Immunohistomorphometry.

Medicina (Kaunas, Lithuania)

Chaushu L,Rahmanov Gavrielov M,Chaushu G,Vered M

Fri Apr 24 00:00:00 UTC 2020

Ultrastructural morphology is distinct among primary progenitor cell isolates from normal, inflamed, and cryopreserved equine hoof tissue and CD105⁺K14⁺ progenitor cells.

In vitro cellular & developmental biology. Animal

Yang Q,Lopez MJ

Sun Sep 01 00:00:00 UTC 2019

Human nail stem cells are retained but hypofunctional during aging.

Journal of molecular histology

Shi J,Lv Z,Nie M,Lu W,Liu C,Tian Y,Li L,Zhang G,Ren R,Zhang Z,Kang H

Fri Jun 01 00:00:00 UTC 2018

Human nail stem cells are retained but hypofunctional during aging.

Journal of molecular histology

Shi J,Lv Z,Nie M,Lu W,Liu C,Tian Y,Li L,Zhang G,Ren R,Zhang Z,Kang H

Fri Jun 01 00:00:00 UTC 2018

Human nail stem cells are retained but hypofunctional during aging.

Journal of molecular histology

Shi J,Lv Z,Nie M,Lu W,Liu C,Tian Y,Li L,Zhang G,Ren R,Zhang Z,Kang H

Fri Jun 01 00:00:00 UTC 2018

Identification of transcription factors that promote the differentiation of human pluripotent stem cells into lacrimal gland epithelium-like cells.

NPJ aging and mechanisms of disease

Hirayama M,Ko SBH,Kawakita T,Akiyama T,Goparaju SK,Soma A,Nakatake Y,Sakota M,Chikazawa-Nohtomi N,Shimmura S,Tsubota K,Ko MSH

Mon Mar 18 00:00:00 UTC 2024

Identification of transcription factors that promote the differentiation of human pluripotent stem cells into lacrimal gland epithelium-like cells.

NPJ aging and mechanisms of disease

Hirayama M,Ko SBH,Kawakita T,Akiyama T,Goparaju SK,Soma A,Nakatake Y,Sakota M,Chikazawa-Nohtomi N,Shimmura S,Tsubota K,Ko MSH

Mon Mar 18 00:00:00 UTC 2024

Characterization of slow cycling corneal limbal epithelial cells identifies putative stem cell markers.

Scientific reports

Sartaj R,Zhang C,Wan P,Pasha Z,Guaiquil V,Liu A,Liu J,Luo Y,Fuchs E,Rosenblatt MI

Mon Jun 19 00:00:00 UTC 2017

Characterization of slow cycling corneal limbal epithelial cells identifies putative stem cell markers.

Scientific reports

Sartaj R,Zhang C,Wan P,Pasha Z,Guaiquil V,Liu A,Liu J,Luo Y,Fuchs E,Rosenblatt MI

Mon Jun 19 00:00:00 UTC 2017

LIM Homeobox Domain 2 Is Required for Corneal Epithelial Homeostasis.

Stem cells (Dayton, Ohio)

Sartaj R,Chee RI,Yang J,Wan P,Liu A,Guaiquil V,Fuchs E,Rosenblatt MI

Mon Feb 01 00:00:00 UTC 2016

LIM Homeobox Domain 2 Is Required for Corneal Epithelial Homeostasis.

Stem cells (Dayton, Ohio)

Sartaj R,Chee RI,Yang J,Wan P,Liu A,Guaiquil V,Fuchs E,Rosenblatt MI

Mon Feb 01 00:00:00 UTC 2016

Survival of skin cancer stem cells requires the Ezh2 polycomb group protein.

Carcinogenesis

Adhikary G,Grun D,Balasubramanian S,Kerr C,Huang JM,Eckert RL

Wed Jul 01 00:00:00 UTC 2015

Survival of skin cancer stem cells requires the Ezh2 polycomb group protein.

Carcinogenesis

Adhikary G,Grun D,Balasubramanian S,Kerr C,Huang JM,Eckert RL

Wed Jul 01 00:00:00 UTC 2015

Identification of a population of epidermal squamous cell carcinoma cells with enhanced potential for tumor formation.

PloS one

Adhikary G,Grun D,Kerr C,Balasubramanian S,Rorke EA,Vemuri M,Boucher S,Bickenbach JR,Hornyak T,Xu W,Fisher ML,Eckert RL

Mon Oct 13 00:00:00 UTC 2014

Identification of a population of epidermal squamous cell carcinoma cells with enhanced potential for tumor formation.

PloS one

Adhikary G,Grun D,Kerr C,Balasubramanian S,Rorke EA,Vemuri M,Boucher S,Bickenbach JR,Hornyak T,Xu W,Fisher ML,Eckert RL

Mon Oct 13 00:00:00 UTC 2014

Distribution of label-retaining cells in the limbal epithelium of a mouse eye.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society

Zhao J,Mo V,Nagasaki T

Sun Feb 01 00:00:00 UTC 2009

Distribution of label-retaining cells in the limbal epithelium of a mouse eye.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society

Zhao J,Mo V,Nagasaki T

Sun Feb 01 00:00:00 UTC 2009

GW bodies: cytoplasmic compartments in normal human skin.

The Journal of investigative dermatology

Zee JM,Shideler KK,Eystathioy T,Bruecks AK,Fritzler MJ,Mydlarski PR

Mon Dec 01 00:00:00 UTC 2008

GW bodies: cytoplasmic compartments in normal human skin.

The Journal of investigative dermatology

Zee JM,Shideler KK,Eystathioy T,Bruecks AK,Fritzler MJ,Mydlarski PR

Mon Dec 01 00:00:00 UTC 2008

Abnormal epithelial homeostasis in the cornea of mice with a destrin deletion.

Molecular vision

Zhang W,Zhao J,Chen L,Urbanowicz MM,Nagasaki T

Fri Dec 12 00:00:00 UTC 2008

Abnormal epithelial homeostasis in the cornea of mice with a destrin deletion.

Molecular vision

Zhang W,Zhao J,Chen L,Urbanowicz MM,Nagasaki T

Fri Dec 12 00:00:00 UTC 2008

Bioinformatics

Protein Aliases: C K1CO; CK-15; cytokeratin 15; Cytokeratin-15; K15; keratin 15, type I; keratin complex 1, acidic, gene 15; Keratin, type I cytoskeletal 15; Keratin-15; keratin-15, basic; keratin-15, beta; KRT1; krt15 {ECO:0000250|UniProtKB:P19012}; type I cytoskeletal 15; Type I keratin Ka15

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Gene Aliases: AI528832; CK15; K15; K1CO; Ka15; Krt1-15; KRT15; KRTB

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UniProt ID: (Human) P19012, (Mouse) Q61414, (Rat) Q6IFV3

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Entrez Gene ID: (Human) 3866, (Mouse) 16665, (Rat) 287700

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Function(s)

structural constituent of cytoskeleton protein binding scaffold protein binding structural molecule activity

Process(es)

cytoskeleton organization epidermis development mitophagy in response to mitochondrial depolarization intermediate filament-based process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Cytokeratin 15 Polyclonal Antibody

Cytokeratin 15 Antibody (10137-1-AP) in IHC (P)

Product Details

10137-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Immunoprecipitation (IP)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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