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Proteintech
Cytokeratin 17 Polyclonal Antibody
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Product Details
18502-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Cytokeratin 17 Fusion Protein Ag13351 (1-432 aa encoded by BC011901)
Conjugate
Form
Liquid
Concentration
0.22 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MTTSIRQFT SSSSIKGSSG LGGGSSRTSC RLSGGLGAGS CRLGSAGGLG STLGGSSYSS CYSFGSGGGY GSSFGGVDGL LAGGEKATMQ NLNDRLASYL DKVRALEEAN TELEVKIRDW YQRQAPGPAR DYSQYYRTIE ELQNKILTAT VDNANILLQI DNARLAADDF RTKFETEQAL RLSVEADING LRRVLDELTL ARADLEMQIE NLKEELAYLK KNHEEEMNAL RGQVGGEINV EMDAAPGVDL SRILNEMRDQ YEKMAEKNRK DAEDWFFSKT EELNREVATN SELVQSGKSE ISELRRTMQA LEIELQSQLS MKASLEGNLA ETENRYCVQL SQIQGLIGSV EEQLAQLRCE MEQQNQEYKI LLDVKTRLEQ EIATYRRLLE GEDAHLTQYK KEPVTTRQVR TIVEEVQDGK VISSREQVHQ TTR (1-432 aa encoded by BC011901)
Target Information
Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately40 kDa and approximately68 kDa and isoelectric pH between 4. 9 - 7. 8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 39.1; CK-17; CK17; Cytokeratin-17; hard keratin; K17; keratin 17, type I; keratin complex 1, acidic, gene 17; Keratin, type I cytoskeletal 17; Keratin-17; krt17 {ECO:0000250|UniProtKB:Q04695}; Type I keratin Ka17
Gene Aliases: 39.1; CK-17; K17; Ka17; Krt1-17; KRT17; PC; PC2; PCHC1
UniProt ID: (Human) Q04695, (Mouse) Q9QWL7, (Rat) Q6IFU8
Entrez Gene ID: (Human) 3872, (Mouse) 16667, (Rat) 287702
morphogenesis of an epithelium
signal transduction
positive regulation of cell growth
hair follicle morphogenesis
keratinization
intermediate filament organization
positive regulation of translation
positive regulation of hair follicle development
epidermis development
intermediate filament-based process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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