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Product Details
MA1-90930
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgM
Class
Monoclonal
Type
Antibody
Clone
LH8
Immunogen
The 50,000 Mr band (including K14 )cut from an SDS-polyacrylamide gel and Triton X-100 extracted cytoskeleton pellet from cultured human foreskin keratinocytes.
Conjugate
Form
Liquid
Concentration
0.8 mg/mL
Purification
IgG fraction
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_1955730
Product Specific Information
MA1-90930 detects Cytokeratin 5 + 14 from human samples.
Target Information
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 58 kDa cytokeratin; CK-14; CK-5; cytokeratin 14; Cytokeratin-14; Cytokeratin-5; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; K14; K5; keratin 14, type I; keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5, type II; Keratin, type I cytoskeletal 14; Keratin, type II cytoskeletal 5; Keratin-14; Keratin-5; Type-II keratin Kb5
Gene Aliases: CK14; CK5; DDD; DDD1; EBS2; EBS3; EBS4; K14; K5; KRT14; KRT5; KRT5A; NFJ
UniProt ID: (Human) P02533, (Human) P13647
Entrez Gene ID: (Human) 3861, (Human) 3852
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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