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Progen
Cytokeratin 8 Monoclonal Antibody (Ks8.7)
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Product Details
690038S
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Hamster,
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
Ks8.7
Immunogen
Cytoskeletal Proteins From Cultured Hela Cells
Conjugate
Form
Liquid
Concentration
50 µg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 0.5% BSA
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Ks 8.7 represents an excellent marker to discriminate simple epithelia from those of different origin. Polypeptide reacting: MW 52 500 polypeptide (keratin K8; formerly also designated cytokeratin 8) of human epithelia.Reactivity on cultured cell lines: MCF-7Tumors specifically detected: All adenocarcinoma tested; undifferentiated carcinoma; cervix carcinoma; hepatocellular carcinoma.
Target Information
Cytokeratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. Cutokeratin 8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CK-8; Cytokeratin-8; K8; keratin 8; keratin 8, type II; Keratin, type II cytoskeletal 8; keratin, type II cytoskeletal 8-like protein; Keratin-8; Type-II keratin Kb8
Gene Aliases: CARD2; CK-8; CK8; CYK8; K2C8; K8; KO; KRT8
UniProt ID: (Human) P05787
Entrez Gene ID: (Human) 3856, (Chinese hamster) 100759488
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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