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Invitrogen
D4-GDI Monoclonal Antibody (97A1015)
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Product Details
MA1-41085
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Mouse
/ IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
97A1015
Immunogen
Synthetic peptide corresponding to a region containing the Fas-induced cleavage site of human D4-GDI.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2059600
Product Specific Information
Suggested positive control: anti-Fas treated Jurkat (10 ng/mL), antigen standard for ARHGDIB (transient overexpression lysate).
Target Information
Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: D4; d4 gdi; GDI LYGDI; Ly-GDI; Rho GDI 2; Rho GDP dissociation inhibitor (GDI) beta; Rho GDP-dissociation inhibitor 2; Rho-GDI beta
Gene Aliases: ARHGDIB; D4; GDIA2; GDID4; Ly-GDI; LYGDI; RAP1GN1; RhoGDI2
UniProt ID: (Human) P52566, (Mouse) Q61599
Entrez Gene ID: (Human) 397, (Mouse) 11857
metabolic process
negative regulation of trophoblast cell migration
movement of cell or subcellular component
negative regulation of cell adhesion
multicellular organism development
regulation of Rho protein signal transduction
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction
cellular response to redox state
regulation of actin cytoskeleton reorganization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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