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Proteintech
DAP5 Polyclonal Antibody
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Product Details
17728-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DAP5 Fusion Protein Ag12125 (563-907 aa encoded by BC043149)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: EAVNGVREM RAPKHFLPEM LSKVIILSLD RSDEDKEKAS SLISLLKQEG IATSDNFMQA FLNVLDQCPK LEVDIPLVKS YLAQFAARAI ISELVSISEL AQPLESGTHF PLFLLCLQQL AKLQDREWLT ELFQQSKVNM QKMLPEIDQN KDRMLEILEG KGLSFLFPLL KLEKELLKQI KLDPSPQTIY KWIKDNISPK LHVDKGFVNI LMTSFLQYIS SEVNPPSDET DSSSAPSKEQ LEQEKQLLLS FKPVMQKFLH DHVDLQVSAL YALQVHCYNS NFPKGMLLRF FVHFYDMEII EEEAFLAWKE DITQEFPGKG KALFQVNQWL TWLETAEEEE SEEEAD (563-907 aa encoded by BC043149)
Target Information
CDK5RAP2 is a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein is localized to the centrosome and Golgi complex and interacts with CDK5R1 and pericentrin (PCNT). CDK5RAP2 plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: aging-associated protein 1; DAP-5; Death-associated protein 5; eIF-4-gamma 2; eIF-4G 2; eIF4G 2; EIF4G2; Eukaryotic translation initiation factor 4 gamma 2; eukaryotic translation initiation factor 4 gamma, 2; eukaryotic translation initiation factor 4G-like 1; FLJ41344; Novel APOBEC-1 target 1; p97; Translation repressor NAT1
Gene Aliases: AA589388; AAG1; DAP-5; DAP5; E130105L11Rik; EIF4G2; NAT1; Natm1; OK/SW-cl.75; P97
UniProt ID: (Human) P78344, (Mouse) Q62448
Entrez Gene ID: (Human) 1982, (Mouse) 13690
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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