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Invitrogen
DCAF12 Polyclonal Antibody
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Product Details
PA5-20939
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Chicken
/ IgY
Class
Polyclonal
Type
Antibody
Immunogen
A 15 amino acid peptide near the carboxy terminus of human TCC52.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11157454
Product Specific Information
A suggested positive control is 293 cell lysate.
PA5-20939 can be used with blocking peptide PEP-1053.
Target Information
Cancer-testis (CT) antigens are a type of antigen whose expression is highly restricted, primarily in normal testis, but aberrantly in different tumor types. Their immunogenicity in cancer patients makes them prime targets for immunotherapy of human tumors. One such CT antigen is TCC52, a novel centrosomal protein. TCC52 is a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. The normal biological function of this protein is not known at this time.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cancer/testis antigen 102; Centrosome-related protein TCC52; DDB1- and CUL4-associated factor 12; similar to WD repeat domain 40A; Testis cancer centrosome-related protein; WD repeat domain 40A; WD repeat-containing protein 40A
Gene Aliases: 1500001L20Rik; 5830424K06Rik; AA420338; AI851081; CT102; DCAF12; KIAA1892; TCC52; WDR40A
UniProt ID: (Human) Q5T6F0, (Mouse) Q8BGZ3
Entrez Gene ID: (Human) 25853, (Mouse) 68970, (Rat) 682812
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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