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Immunogen sequence: SIAWHSEVGL PVYAHIRPRD VEAIPRASTN PSNRKVRAL
Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 77%.
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by Gly-His and Trp-Asp (GH-WD), which may facilitate formation of heterotrimeric or multi-protein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene appears to represent an intronless retrocopy of a related multi-exon gene located on chromosome 9. However, the CDS of this intronless gene remains intact, it is conserved in other mammalian species, it is known to be transcribed, and it is therefore thought to encode a functional protein. [provided by RefSeq, May 2010].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DDB1 and CUL4 associated factor 12-like 2; DDB1- and CUL4-associated factor 12-like protein 2; WD repeat-containing protein 40C
Gene Aliases: DCAF12L2; WDR40C
UniProt ID: (Human) Q5VW00
Entrez Gene ID: (Human) 340578
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