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Invitrogen
DCAF6 Polyclonal Antibody
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DCAF6 Antibody (PA5-89724) in WB
Western blot analysis of DCAF6 in extracts of various cell lines. Samples were incubated with DCAF6 Polyclonal antibody (Product # PA5-89724) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
PA5-89724
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 460-650 of human IQWD1 (NP_0010179771)
Conjugate
Form
Liquid
Concentration
1.36 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2805746
Product Specific Information
Immunogen sequence: DNNNEKLSPK PGTGEPVLSL HYSTEGTTTS TIKLNFTDEW SSIASSSRGI GSHCKSEGQE ESFVPQSSVQ PPEGDSETKA PEESSEDVTK YQEGVSAENP VENHINITQS DKFTAKPLDS NSGERNDLNL DRSCGVPEES ASSEKAKEPE TSDQTSTESA TNENNTNPEP QFQTEATGPS AHEETSTRDS A; Positive Samples: HeLa, LO2; Cellular Location: Nucleus
Target Information
NRIP is a novel 860a.a nuclear protein consisting of seven conserved WD40 domains and one NLS motif. It binds to androgen and glucocorticoid receptors and up regulates their transcriptional activity, thereby functioning as a nuclear receptor coactivator. Role of NRIP has been implicated in cell growth and also in cervical and prostrate cancer thus indicating a therapeutic intervention. Northern Blot analysis detected a high expression of NRIP in skeletal muscle and testis and low expression in heart, prostrate and adrenal gland.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Androgen receptor complex-associated protein; ARCAP; DDB1- and CUL4-associated factor 6; IQ motif and WD repeat-containing protein 1; IQ motif and WD repeats 1; NRIP; Nuclear receptor interaction protein
Gene Aliases: 1200006M05Rik; ARCAP; DCAF6; IQWD1; MSTP055; NRIP; PC326
UniProt ID: (Human) Q58WW2
Entrez Gene ID: (Human) 55827
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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