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Recommended positive controls: NT2D1, PC-3, U87-MG, SK-N-SH, human DCTD-transfected 293T cells.
Predicted reactivity: Mouse (94%), Rat (94%), Zebrafish (90%), Xenopus laevis (90%), Chicken (90%), Rhesus Monkey (97%), Bovine (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer. This protein uses zinc as a cofactor for its activity. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: dCMP deaminase; Deoxycytidylate deaminase
Gene Aliases: DCTD
UniProt ID: (Human) P32321
Entrez Gene ID: (Human) 1635
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