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Keep as concentrated solution.
Predicted reactivity: Mouse (92%), Rat (92%), Zebrafish (81%), Xenopus laevis (80%), Chicken (86%), Rhesus Monkey (97%), Bovine (92%).
Positive Control: NT2D1, U87-MG, SK-N-SH, DCTD transfected 293T lysates.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer. This protein uses zinc as a cofactor for its activity. Two transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: dCMP deaminase; Deoxycytidylate deaminase
Gene Aliases: DCTD
UniProt ID: (Human) P32321
Entrez Gene ID: (Human) 1635
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