Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: LKGLPVYNKS NFSRFHADSV CKASNRRPSV YLPTREYPSE QIIVTEKTNI LLRYLHQQWD KKNAAKKRDQ EQVELE
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
Functions as a component of numerous distinct DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:17452440, PubMed:28437394, PubMed:28302793, PubMed:31686031, PubMed:31819272). In the DCX complexes, acts as a scaffolding subunit required to stabilize the complex (PubMed:31686031, PubMed:31819272). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cross-immune reaction antigen PCIA1; DET1- and DDB1-associated protein 1; PCIA-1; Placenta cross-immune reaction antigen 1
Gene Aliases: C19orf58; DDA1; PCIA1
UniProt ID: (Human) Q9BW61
Entrez Gene ID: (Human) 79016
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