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Product Details
PA5-60282
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human DDI2. Recombinant protein control fragment (Product #RP-99834).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2640448
Product Specific Information
Immunogen sequence: VDADFELHNF RALCELESGI PAAESQIVYA ERPLTDNHRS LASYGL
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
Target Information
Aspartic protease that mediates the cleavage of NFE2L1/NRF1 at 'Leu-104', thereby promoting release of NFE2L1/NRF1 from the endoplasmic reticulum membrane. Ubiquitination of NFE2L1/NRF1 is a prerequisite for cleavage, suggesting that DDI2 specifically recognizes and binds ubiquitinated NFE2L1/NRF1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DDI1, DNA-damage inducible 1, homolog 2; DNA-damage inducible 1 homolog 2; DNA-damage inducible protein 2 (DDI2); Protein DDI1 homolog 2; RP4-680D5.5
Gene Aliases: DDI2
UniProt ID: (Human) Q5TDH0
Entrez Gene ID: (Human) 84301
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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