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Invitrogen
DDX10 Polyclonal Antibody
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Product Details
PA5-52086
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human DDX10. Recombinant protein control fragment (Product #RP-102449).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2640458
Product Specific Information
Immunogen sequence: KVPVKEIKIN PEKLIDVQKK LESILAQDQD LKERAQRCFV SYVRSVYLMK DKEVFDVSKL PIPEYALSLG LAVAPRVRFL QKMQKQPTKE LVRSQADKVI EPRAPSLTND EVEEFRAYFN EKMSILQKGG KRLEGTEHRQ DNDTGNEE
Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 78%.
Target Information
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it may be involved in ribosome assembly. Fusion of this gene and the nucleoporin gene, NUP98, by inversion 11 (p15q22) chromosome translocation is found in the patients with de novo or therapy-related myeloid malignancies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DDX10-NUP98 fusion protein type 2; DEAD (Asp-Glu-Ala-Asp) box polypeptide 10; DEAD box protein 10; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 10 (RNA helicase); Probable ATP-dependent RNA helicase DDX10
Gene Aliases: DDX10; HRH-J8
UniProt ID: (Human) Q13206
Entrez Gene ID: (Human) 1662
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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