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Immunogen sequence: EIKMEDILCV LTRDDCFKGK RWGAQKSHAV GPQEIRERAT VLQTVFEDYV HSSERRVSWA KKALQSFIQA YATYPRELKH IFHVRSLHLG HVAKSFGLRD APRNLSALTR KKRKAHVKRP DLHKKTQSKH SLAEILRSEY SSGMEADIAK VKKQNAPGEP GGRPLQHSLQ PTPCFGRGKT LKWRKTQKGV QRDSKTSQKV; Positive Samples: A-549; Cellular Location: Nucleus, nucleolus
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX31 is a member of this family. The function of this member has not been determined. Alternative splicing of this gene generates 2 transcript variants.
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Protein Aliases: ATP-dependent DNA helicase DDX31; DEAD (Asp-Glu-Ala-Asp) box polypeptide 31; DEAD box protein 31; DEAD/DEXH helicase DDX31; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 31; G2 helicase; Helicain; Probable ATP-dependent RNA helicase DDX31; protein phosphatase 1, regulatory subunit 25
Gene Aliases: 5830444G11Rik; DDX31; Gm997; PPP1R25
UniProt ID: (Human) Q9H8H2, (Mouse) Q6NZQ2
Entrez Gene ID: (Human) 64794, (Mouse) 227674, (Rat) 311835
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