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Invitrogen
DDX41 Polyclonal Antibody
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Product Details
PA5-28260
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human DDX41. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2545736
Product Specific Information
Recommended positive controls: A431, H1299.
Predicted reactivity: Mouse (99%), Rat (99%), Chicken (95%), Chimpanzee (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Probable ATP-dependent RNA helicase DDX41 is a DEAD box protein characterized by the conserved motif Asp-Glu-Ala-Asp. It is required during post-transcriptional gene expression and may be involved in pre-mRNA splicing. Mutations affecting the gene can result in myeloproliferative/lymphoproliferative neoplasms, familial (MPLPF).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2900024F02Rik; Abstrakt; DEAD (Asp-Glu-Ala-Asp) box polypeptide 41; DEAD box protein 41; DEAD box protein abstrakt homolog; DEAD-box protein abstrakt; Probable ATP-dependent RNA helicase DDX41; putative RNA helicase
Gene Aliases: ABS; DDX41; MPLPF
UniProt ID: (Human) Q9UJV9
Entrez Gene ID: (Human) 51428
mRNA splicing, via spliceosome
apoptotic process
cell proliferation
RNA secondary structure unwinding
cell differentiation
regulation of type I interferon production
positive regulation of type I interferon production
cellular response to interferon-beta
positive regulation of transcription from RNA polymerase II promoter
defense response to virus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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