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Product Details
H00051428-M01
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
2F4
Immunogen
DDX41 (NP_057306, 523 a.a. approximately 622 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: TGRSGNTGIA TTFINKACDE SVLMDLKALL LEAKQKVPPV LQVLHCGDES MLDIGGERGC AFCGGLGHRI TDCPKLEAMQ TKQVSNIGRK DYLAHSSMDF
Target Information
Probable ATP-dependent RNA helicase DDX41 is a DEAD box protein characterized by the conserved motif Asp-Glu-Ala-Asp. It is required during post-transcriptional gene expression and may be involved in pre-mRNA splicing. Mutations affecting the gene can result in myeloproliferative/lymphoproliferative neoplasms, familial (MPLPF).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2900024F02Rik; Abstrakt; DEAD (Asp-Glu-Ala-Asp) box polypeptide 41; DEAD box protein 41; DEAD box protein abstrakt homolog; DEAD-box protein abstrakt; Probable ATP-dependent RNA helicase DDX41; putative RNA helicase
Gene Aliases: ABS; DDX41; MPLPF
UniProt ID: (Human) Q9UJV9
Entrez Gene ID: (Human) 51428
mRNA splicing, via spliceosome
apoptotic process
cell proliferation
RNA secondary structure unwinding
cell differentiation
regulation of type I interferon production
positive regulation of type I interferon production
cellular response to interferon-beta
positive regulation of transcription from RNA polymerase II promoter
defense response to virus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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