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Proteintech
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Immunogen sequence: GLDVKHLIL VVNYSCPNHY EDYVHRAGRT GRAGNKGYAY TFITEDQARY AGDIIKALEL SGTAVPPDLE KLWSDFKDQQ KAEGKIIKKS SGFSGKGFKF DETEQALANE RKKLQKAALG LQDSDDEDAA VDIDEQIESM FNSKKRVKDM AAPGTSSVPA PTAGNAEKLE IAKRLALRIN AQKNLGIESQ DVMQQATNAI LRGGTILAPT VSAKTIAEQL AEKINAKLNY VPLEKQEEER QDGGQNESFK RYEEELEIND FPQTARWKVT SKEALQRISE YSEAAITIRG TYFPPGKEPK EGERKIYLAI ESANELAVQK AKAEITRLIK EELIRLQNSY QPTNKGRYKV L (682-1031 aa encoded by BC012304)
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the 17S U2 snRNP complex; it plays an important role in pre-mRNA splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DEAD (Asp-Glu-Ala-Asp) box polypeptide 46; DEAD box polypeptide 46; DEAD box protein 46; Helicase of 117.4 kDa; Probable ATP-dependent RNA helicase DDX46; PRP5 homolog; Prp5-like DEAD-box protein; RNA helicase
Gene Aliases: 2200005K02Rik; 8430438J23Rik; AI325430; AI957095; DDX46; Hel117; KIAA0801; mKIAA0801; Prp5; PRPF5
UniProt ID: (Human) Q7L014, (Rat) Q62780, (Mouse) Q569Z5
Entrez Gene ID: (Human) 9879, (Rat) 245957, (Mouse) 212880
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