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Sequence of this protein is as follows: MGLSSQNGQL RGPVKPTGGP GGGGTQTQQQ MNQLKNTNTI NNGTQQQAQS MTTTIKPGDD WKKTLKLPPK DLRIKTSDVT STKGNEFEDY CLKRELLMGI FEMGWEKPSP IQEESIPIAL SGRDILARAK NGTGKSGAYL IPLLERLDLK KDNIQAMVIV PTRELALQVS QICIQVSKHM GGAKVMATTG GTNLRDDIMR LDDTVHVVIA TPGRILDLIK KGVAKVDHVQ MIVLDEADKL LSQDFVQIME DIILTLPKNR QILLYSATFP LSVQKFMNSH LQKPYEINLM EELTLKGVTQ YYAYVTERQK VHCLNTLFSR LQINQSIIFC NSSQRVELLA KKISQLGYSC FYIHAKMRQE HRNRVFHDFR NGLCRNLVCT DLFTRGIDIQ AVNVVINFDF PKLAETYLHR IGRSGRFGHL GLAINLITYD DRFNLKSIEE QLGTEIKPIP SNIDKSLYVA EYHSEPVEDE KP
This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing.
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Protein Aliases: ATP-dependent RNA helicase p54; D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 6; DEAD (Asp-Glu-Ala-Asp) box helicase 6; DEAD (Asp-Glu-Ala-Asp) box polypeptide 6; DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 6; DEAD box protein 6; DEAD box-6; DEAD-box protein 6; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 6; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 6 (RNA helicase, 54kD); Oncogene RCK; Oncogene RCK homolog; Probable ATP-dependent RNA helicase DDX6
Gene Aliases: 1110001P04Rik; DDX6; E230023J21Rik; HLR2; mRCK/P54; P54; RCK
UniProt ID: (Human) P26196, (Mouse) P54823
Entrez Gene ID: (Human) 1656, (Mouse) 13209
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