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Proteintech
DEK Monoclonal Antibody (5E3A6)
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Product Details
66194-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
5E3A6
Immunogen
DEK Fusion Protein Ag8225 (1-375 aa encoded by BC035259)
Conjugate
Form
Liquid
Concentration
1.61 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSASAPAAE GEGTPTQPAS EKEPEMPGPR EESEEEEDED DEEEEEEEKE KSLIVEGKRE KKKVERLTMQ VSSLQREPFT IAQGKGQKLC EIERIHFFLS KKKTDELRNL HKLLYNRPGT VSSLKKNVGQ FSGFPFEKGS VQYKKKEEML KKFRNAMLKS ICEVLDLERS GVNSELVKRI LNFLMHPKPS GKPLPKSKKT CSKGSKKERN SSGMARKAKR TKCPEILSDE SSSDEDEKKN KEESSDDEDK ESEEEPPKKT AKREKPKQKA TSKSKKSVKS ANVKKADSST TKKNQNSSKK ESESEDSSDD EPLIKKLKKP PTDEELKETI KKLLASANLE EVTMKQICKK VYENYPTYDL TERKDFIKTT VKELIS (1-375 aa encoded by B C035259)
Target Information
DEK is a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DEK oncogene (DNA binding); Protein DEK
Gene Aliases: 1810019E15Rik; D13H6S231E; D6S231E; DEK
UniProt ID: (Human) P35659, (Rat) Q6AXS3, (Mouse) Q7TNV0
Entrez Gene ID: (Human) 7913, (Rat) 306817, (Mouse) 110052
biological_process
chromatin modification
regulation of double-strand break repair
regulation of double-strand break repair via nonhomologous end joining
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
signal transduction
covalent chromatin modification
viral genome replication
positive regulation of gene expression, epigenetic
cell quiescence
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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