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Immunogen sequence: LDTSALSVQG NFDLNSKSKL QENFCTRSIQ IPANRSKTAM SKCPIFPMAR SISTSGPLDK EDTGRQKLIS TGSLPATLQG ATDSLGL
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 82%.
Probable guanine nucleotide exchange factor (GEF) which may activate RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. According to PubMed:8056341, it may bind to ISRE-like element (interferon-stimulated response element) of MYC P2 promoter.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: c-myc promoter binding protein; C-myc promoter-binding protein; DENN domain-containing protein 4A; DENN/MADD domain containing 4A
Gene Aliases: DENND4A; IRLB; MYCPBP
UniProt ID: (Human) Q7Z401
Entrez Gene ID: (Human) 10260
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