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Product Details
PA5-53255
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human DENND4C. Recombinant protein control fragment (Product #RP-91444).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2640519
Product Specific Information
Immunogen sequence: PSGIFDVNSR KSSTGSISNV LFSTQDPVED AVFGEATNLK KNGDRGEKRQ KHFPERSCSF SSESRAGMLL KKSSLDSNSS EMAIMMGADA KILTAALTCP KTSLLHIART HSFENVSCHL PDSRTCMSES TW
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 86%.
Target Information
DENND4C is guanine nucleotide exchange factor (GEF) activating RAB10. It promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB10 into its active GTP-bound form. Thereby, stimulates SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane in response to insulin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DENN domain-containing protein 4C; DENN/MADD domain containing 4A pseudogene; DENN/MADD domain containing 4C; likely ortholog of H. sapiens chromosome 9 open reading frame 55 (C9orf55)
Gene Aliases: 1700065A05Rik; AA420392; bA513M16.3; C9orf55; C9orf55B; DENND4C; RAB10GEF; RGD1308489
UniProt ID: (Human) Q5VZ89, (Mouse) A6H8H2
Entrez Gene ID: (Human) 55667, (Mouse) 329877, (Rat) 313340
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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