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Invitrogen
DENND5A Polyclonal Antibody
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Product Details
PA5-62705
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human DENND5A. Recombinant protein control fragment (Product #RP-100833).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2640521
Product Specific Information
Immunogen sequence: MHNAEYDVLH APPADDRDQS SMEDGEDTPV TKLQR
Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 80%.
Target Information
DENND5A (DENN domain-containing protein 5A) is a guanine nucleotide exchange factor (GEF) which activates RAB6A and RAB39A/RAB39B. It promotes the exchange of GDP to GTP by converting inactive GDP-bound Rab proteins to their active GTP form. DENND5A is also involved in the negative regulation of neurtie outgrowth. Mutations affecting this gene can result in epileptic encephalopathy, early infantile, 49 (EIEE49).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DENN domain-containing protein 5A; DENN/MADD domain containing 5A; RAB6 interacting protein 1; Rab6-interacting protein 1; Rab6IP1
Gene Aliases: DENND5A; KIAA1091; RAB6IP1
UniProt ID: (Human) Q6IQ26
Entrez Gene ID: (Human) 23258
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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