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Invitrogen
DEPDC1 Polyclonal Antibody
FIGURE: 1 / 7
DEPDC1 Antibody (PA5-34864) in ICC/IF
DEPDC1 Polyclonal Antibody detects DEPDC1 protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: DEPDC1 protein stained by DEPDC1 Polyclonal Antibody (Product # PA5-34864) diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 µm.
Product Details
PA5-34864
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human DEPDC1. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2552216
Product Specific Information
Recommended positive controls: 293T, A431, HepG2.
Predicted reactivity: Rat (87%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: cell cycle control protein SDP35; DEP domain-containing protein 1A
Gene Aliases: DEP.8; DEPDC1; DEPDC1-V2; DEPDC1A; SDP35
UniProt ID: (Human) Q5TB30
Entrez Gene ID: (Human) 55635
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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