Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Peptide sequence: FFFNMLFVFR YCRMLEEGSF RGRTADFVFM FLFGGVLMTL LGLLGSLFFL
Sequence homology: Cow: 100%; Dog: 100%; Goat: 92%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
The protein encoded by this gene belongs to the derlin family, and resides in the endoplasmic reticulum (ER). Proteins that are unfolded or misfolded in the ER must be refolded or degraded to maintain the homeostasis of the ER. This protein appears to be involved in the degradation of misfolded glycoproteins in the ER. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Degradation in endoplasmic reticulum protein 3; Der1-like domain family, member 3; Der1-like protein 3; Derlin-3; DERtrin 3; DERtrin-3; MGC71803
Gene Aliases: C22orf14; DER3; DERL3; derlin-3; IZP6; LLN2
UniProt ID: (Human) Q96Q80
Entrez Gene ID: (Human) 91319
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