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Search Thermo Fisher Scientific
Immunogen sequence: MVPKADSGA FLLLFLLVLT VTEPLRPELR CNPGQFACRS GTIQCIPLPW QCDGWATCED ESDEANCPEV TGEVRPHHGK EAVDPRQGRA RGGDPSHFHA VNVAQPVRFS SFLGKCPTGW HHYEGTASCY RVYLSGENYW DAAQTCQRLN GSLATFSTDQ ELRFVLAQEW DQPERSFGWK DQRKLWVGYQ YVITGRNRSL EGRWEVAFKG SSEVFLPPDP IFASAMSEND NVFCAQLQCF HFPTLRHHDL HSWHAESCYE KSSFLCKRSQ TCVDIKDNVV DEGFYFTPKG DDPCLSCTCH G (1-300 aa encoded by BC032430)
Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DiGeorge syndrome critical region protein 2; DiGeorge syndrome gene c; DiGeorge syndrome protein C; integral membrane protein deleted in DiGeorge syndrome; Integral membrane protein DGCR2/IDD; Seizure-related membrane-bound adhesion protein
Gene Aliases: 9930034O06Rik; DGCR2; DGS-C; Dgsc; IDD; KIAA0163; LAN; mKIAA0163; SEZ-12; Sez12
UniProt ID: (Human) P98153, (Mouse) P98154
Entrez Gene ID: (Human) 9993, (Rat) 360742, (Mouse) 13356
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