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Product Details
PA5-51474
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human DGCR2. Recombinant protein control fragment (Product #RP-91328).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2640544
Product Specific Information
Immunogen sequence: RFSRKCPTGW HHYEGTASCY RVYLSGENYW DAAQTCQRLN GSLATFSTDQ ELRFVLAQEW DQPERSFGWK DQRKLWVGYQ YVITGRNRSL EGRWEVAFKG SSEVFLPPDP IFASAMSEND NVFCAQLQCF HFPTLRHHDL HSWHAESCYE KSSFLCKRSQ TCVDIKDNVV DEGFYFTPK
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.
Target Information
Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DiGeorge syndrome critical region protein 2; integral membrane protein deleted in DiGeorge syndrome; Integral membrane protein DGCR2/IDD
Gene Aliases: DGCR2; DGS-C; IDD; KIAA0163; LAN; SEZ-12
UniProt ID: (Human) P98153
Entrez Gene ID: (Human) 9993
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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