Product References
METTL14-dependent maturation of pri-miR-17 regulates mitochondrial homeostasis and induces chemoresistance in colorectal cancer.
Cell death & disease
Sun K,Chen L,Li Y,Huang B,Yan Q,Wu C,Lai Q,Fang Y,Cai J,Liu Y,Chen J,Wang X,Zhu Y,Dong S,Tan J,Li A,Liu S,Zhang Y
Tue Feb 21 00:00:00 UTC 2023
METTL3 Promotes Osteo/Odontogenic Differentiation of Stem Cells by Inhibiting miR-196b-5p Maturation.
Stem cells international
Han X,Li G,Yang H,Zhang C,Cao Y,Wang N,Ge L,Fan Z
Mon Jun 19 00:00:00 UTC 2023
METTL3 Promotes Osteo/Odontogenic Differentiation of Stem Cells by Inhibiting miR-196b-5p Maturation.
Stem cells international
Han X,Li G,Yang H,Zhang C,Cao Y,Wang N,Ge L,Fan Z
Mon Jun 19 00:00:00 UTC 2023
METTL3 Promotes Osteo/Odontogenic Differentiation of Stem Cells by Inhibiting miR-196b-5p Maturation.
Stem cells international
Han X,Li G,Yang H,Zhang C,Cao Y,Wang N,Ge L,Fan Z
Mon Jun 19 00:00:00 UTC 2023
Therapeutic targeting m6A-guided miR-146a-5p signaling contributes to the melittin-induced selective suppression of bladder cancer.
Cancer letters
Yan R,Dai W,Wu R,Huang H,Shu M
Sat May 28 00:00:00 UTC 2022
Upregulation of DGCR8, a Candidate Predisposing to Schizophrenia in Han Chinese, Contributes to Phenotypic Deficits and Neuronal Migration Delay.
Frontiers in psychiatry
Bi Y,Chen S,Shen Q,Guo Z,Ren D,Yuan F,Niu W,Ji L,Liu L,Han K,Yu T,Yang F,Wu X,Wang L,Li X,Yu S,Xu Y,He L,Shi Y,Zhang J,Li W,He G
Sat Jul 16 00:00:00 UTC 2022
Caspase-mediated cleavage of miRNA processing proteins Drosha, DGCR8, Dicer, and TRBP2 in heat-shocked cells and its inhibition by HSP70 overexpression.
Cell stress & chaperones
Abou Zeid LY,Shanmugapriya S,Rumney RL,Mosser DD
Sat Jan 01 00:00:00 UTC 2022
Perfluorooctane sulfonate induces heart toxicity involving cardiac apoptosis and inflammation in rats.
Experimental and therapeutic medicine
Xu D,Li L,Tang L,Guo M,Yang J
Sat Jan 01 00:00:00 UTC 2022
DNA double-strand break-derived RNA drives TIRR/53BP1 complex dissociation.
Cell reports
Ketley RF,Battistini F,Alagia A,Mondielli C,Iehl F,Balikçi E,Huber KVM,Orozco M,Gullerova M
Tue Oct 25 00:00:00 UTC 2022
Principles of signaling pathway modulation for enhancing human naive pluripotency induction.
Cell stem cell
Bayerl J,Ayyash M,Shani T,Manor YS,Gafni O,Massarwa R,Kalma Y,Aguilera-Castrejon A,Zerbib M,Amir H,Sheban D,Geula S,Mor N,Weinberger L,Naveh Tassa S,Krupalnik V,Oldak B,Livnat N,Tarazi S,Tawil S,Wildschutz E,Ashouokhi S,Lasman L,Rotter V,Hanna S,Ben-Yosef D,Novershtern N,Viukov S,Hanna JH
Thu Sep 02 00:00:00 UTC 2021
Control of ribosomal protein synthesis by the Microprocessor complex.
Science signaling
Jiang X,Prabhakar A,Van der Voorn SM,Ghatpande P,Celona B,Venkataramanan S,Calviello L,Lin C,Wang W,Black BL,Floor SN,Lagna G,Hata A
Tue Feb 23 00:00:00 UTC 2021
DGCR8 deficiency impairs macrophage growth and unleashes the interferon response to mycobacteria.
Life science alliance
Killy B,Bodendorfer B,Mages J,Ritter K,Schreiber J,Hölscher C,Pracht K,Ekici A,Jäck HM,Lang R
Tue Jun 01 00:00:00 UTC 2021
Global miRNA dosage control of embryonic germ layer specification.
Nature
Cui Y,Lyu X,Ding L,Ke L,Yang D,Pirouz M,Qi Y,Ong J,Gao G,Du P,Gregory RI
Sat May 01 00:00:00 UTC 2021
Global miRNA dosage control of embryonic germ layer specification.
Nature
Cui Y,Lyu X,Ding L,Ke L,Yang D,Pirouz M,Qi Y,Ong J,Gao G,Du P,Gregory RI
Sat May 01 00:00:00 UTC 2021
Global miRNA dosage control of embryonic germ layer specification.
Nature
Cui Y,Lyu X,Ding L,Ke L,Yang D,Pirouz M,Qi Y,Ong J,Gao G,Du P,Gregory RI
Sat May 01 00:00:00 UTC 2021
Global miRNA dosage control of embryonic germ layer specification.
Nature
Cui Y,Lyu X,Ding L,Ke L,Yang D,Pirouz M,Qi Y,Ong J,Gao G,Du P,Gregory RI
Sat May 01 00:00:00 UTC 2021
Inhibition of METTL3/m6A/miR126 promotes the migration and invasion of endometrial stromal cells in endometriosis†.
Biology of reproduction
Li X,Xiong W,Long X,Dai X,Peng Y,Xu Y,Zhang Z,Zhang L,Liu Y
Mon Nov 15 00:00:00 UTC 2021
Inhibition of METTL3/m6A/miR126 promotes the migration and invasion of endometrial stromal cells in endometriosis†.
Biology of reproduction
Li X,Xiong W,Long X,Dai X,Peng Y,Xu Y,Zhang Z,Zhang L,Liu Y
Mon Nov 15 00:00:00 UTC 2021
YB1 regulates miR-205/200b-ZEB1 axis by inhibiting microRNA maturation in hepatocellular carcinoma.
Cancer communications (London, England)
Liu X,Chen D,Chen H,Wang W,Liu Y,Wang Y,Duan C,Ning Z,Guo X,Otkur W,Liu J,Qi H,Liu X,Lin A,Xia T,Liu HX,Piao HL
Thu Jul 01 00:00:00 UTC 2021
YB1 regulates miR-205/200b-ZEB1 axis by inhibiting microRNA maturation in hepatocellular carcinoma.
Cancer communications (London, England)
Liu X,Chen D,Chen H,Wang W,Liu Y,Wang Y,Duan C,Ning Z,Guo X,Otkur W,Liu J,Qi H,Liu X,Lin A,Xia T,Liu HX,Piao HL
Thu Jul 01 00:00:00 UTC 2021
YB1 regulates miR-205/200b-ZEB1 axis by inhibiting microRNA maturation in hepatocellular carcinoma.
Cancer communications (London, England)
Liu X,Chen D,Chen H,Wang W,Liu Y,Wang Y,Duan C,Ning Z,Guo X,Otkur W,Liu J,Qi H,Liu X,Lin A,Xia T,Liu HX,Piao HL
Thu Jul 01 00:00:00 UTC 2021
DGCR8-dependent efficient pri-miRNA processing of human pri-miR-9-2.
The Journal of biological chemistry
Nogami M,Miyamoto K,Hayakawa-Yano Y,Nakanishi A,Yano M,Okano H
Fri Aug 27 00:00:00 UTC 2021
HPV16 E6 enhances the radiosensitivity in HPV-positive human head and neck squamous cell carcinoma by regulating the miR-27a-3p/SMG1 axis.
Infectious agents and cancer
Long D,Xu L,Deng Z,Guo D,Zhang Y,Liu Z,Zhang C
Fri Aug 13 00:00:00 UTC 2021
HPV16 E6 enhances the radiosensitivity in HPV-positive human head and neck squamous cell carcinoma by regulating the miR-27a-3p/SMG1 axis.
Infectious agents and cancer
Long D,Xu L,Deng Z,Guo D,Zhang Y,Liu Z,Zhang C
Fri Aug 13 00:00:00 UTC 2021
METTL3 regulates skeletal muscle specific miRNAs at both transcriptional and post-transcriptional levels.
Biochemical and biophysical research communications
Diao LT,Xie SJ,Lei H,Qiu XS,Huang MC,Tao S,Hou YR,Hu YX,Sun YJ,Zhang Q,Xiao ZD
Fri May 07 00:00:00 UTC 2021
Tumor evolution selectively inactivates the core microRNA machinery for immune evasion.
Nature communications
Song TY,Long M,Zhao HX,Zou MW,Fan HJ,Liu Y,Geng CL,Song MF,Liu YF,Chen JY,Yang YL,Zhou WR,Huang DW,Peng B,Peng ZG,Cang Y
Wed Dec 01 00:00:00 UTC 2021
CircLONP2 enhances colorectal carcinoma invasion and metastasis through modulating the maturation and exosomal dissemination of microRNA-17.
Molecular cancer
Han K,Wang FW,Cao CH,Ling H,Chen JW,Chen RX,Feng ZH,Luo J,Jin XH,Duan JL,Li SM,Ma NF,Yun JP,Guan XY,Pan ZZ,Lan P,Xu RH,Xie D
Wed Mar 18 00:00:00 UTC 2020
Differential roles of human PUS10 in miRNA processing and tRNA pseudouridylation.
Nature chemical biology
Song J,Zhuang Y,Zhu C,Meng H,Lu B,Xie B,Peng J,Li M,Yi C
Sat Feb 01 00:00:00 UTC 2020
DGCR8/miR-106 Axis Enhances Radiosensitivity of Head and Neck Squamous Cell Carcinomas by Downregulating RUNX3.
Frontiers in medicine
Zhang C,Chen H,Deng Z,Long D,Xu L,Liu Z
Sat Jan 02 00:00:00 UTC 2021
DGCR8/miR-106 Axis Enhances Radiosensitivity of Head and Neck Squamous Cell Carcinomas by Downregulating RUNX3.
Frontiers in medicine
Zhang C,Chen H,Deng Z,Long D,Xu L,Liu Z
Sat Jan 02 00:00:00 UTC 2021
Deficient Expression of DGCR8 in Human Testis is Related to Spermatogenesis Dysfunction, Especially in Meiosis I.
International journal of general medicine
Babakhanzadeh E,Khodadadian A,Nazari M,Dehghan Tezerjani M,Aghaei SM,Ghasemifar S,Hosseinnia M,Mazaheri M
Fri Apr 15 00:00:00 UTC 2022
Deficient Expression of DGCR8 in Human Testis is Related to Spermatogenesis Dysfunction, Especially in Meiosis I.
International journal of general medicine
Babakhanzadeh E,Khodadadian A,Nazari M,Dehghan Tezerjani M,Aghaei SM,Ghasemifar S,Hosseinnia M,Mazaheri M
Fri Apr 15 00:00:00 UTC 2022
Genetic deletion of microRNA biogenesis in muscle cells reveals a hierarchical non-clustered network that controls focal adhesion signaling during muscle regeneration.
Molecular metabolism
Luca E,Turcekova K,Hartung A,Mathes S,Rehrauer H,Krützfeldt J
Mon Jun 01 00:00:00 UTC 2020
Oncogenic Biogenesis of pri-miR-17∼92 Reveals Hierarchy and Competition among Polycistronic MicroRNAs.
Molecular cell
Donayo AO,Johnson RM,Tseng HW,Izreig S,Gariepy A,Mayya VK,Wu E,Alam R,Lussier C,Jones RG,Duchaine TF
Thu Jul 25 00:00:00 UTC 2019
Lin28 enhances de novo fatty acid synthesis to promote cancer progression via SREBP-1.
EMBO reports
Zhang Y,Li C,Hu C,Wu Q,Cai Y,Xing S,Lu H,Wang L,Huang D,Sun L,Li T,He X,Zhong X,Wang J,Gao P,Smith ZJ,Jia W,Zhang H
Fri Oct 04 00:00:00 UTC 2019
Biological and RNA regulatory function of MOV10 in mammalian germ cells.
BMC biology
Fu K,Tian S,Tan H,Wang C,Wang H,Wang M,Wang Y,Chen Z,Wang Y,Yue Q,Xu Q,Zhang S,Li H,Xie J,Lin M,Luo M,Chen F,Ye L,Zheng K
Tue May 14 00:00:00 UTC 2019
An Intermediate Pluripotent State Controlled by MicroRNAs Is Required for the Naive-to-Primed Stem Cell Transition.
Cell stem cell
Du P,Pirouz M,Choi J,Huebner AJ,Clement K,Meissner A,Hochedlinger K,Gregory RI
Fri Jun 01 00:00:00 UTC 2018
An Intermediate Pluripotent State Controlled by MicroRNAs Is Required for the Naive-to-Primed Stem Cell Transition.
Cell stem cell
Du P,Pirouz M,Choi J,Huebner AJ,Clement K,Meissner A,Hochedlinger K,Gregory RI
Fri Jun 01 00:00:00 UTC 2018
High-Throughput Characterization of Primary microRNA Transcripts.
Methods in molecular biology (Clifton, N.J.)
Chang TC,Mendell JT
Thu Mar 21 00:00:00 UTC 2019
High-Throughput Characterization of Primary microRNA Transcripts.
Methods in molecular biology (Clifton, N.J.)
Chang TC,Mendell JT
Thu Mar 21 00:00:00 UTC 2019
DGCR8 Promotes Neural Progenitor Expansion and Represses Neurogenesis in the Mouse Embryonic Neocortex.
Frontiers in neuroscience
Hoffmann N,Weise SC,Marinaro F,Vogel T,De Pietri Tonelli D
Thu Oct 01 00:00:00 UTC 2020
DGCR8 Promotes Neural Progenitor Expansion and Represses Neurogenesis in the Mouse Embryonic Neocortex.
Frontiers in neuroscience
Hoffmann N,Weise SC,Marinaro F,Vogel T,De Pietri Tonelli D
Thu Oct 01 00:00:00 UTC 2020
Super-Enhancer-Mediated RNA Processing Revealed by Integrative MicroRNA Network Analysis.
Cell
Suzuki HI,Young RA,Sharp PA
Thu Mar 09 00:00:00 UTC 2017
Super-Enhancer-Mediated RNA Processing Revealed by Integrative MicroRNA Network Analysis.
Cell
Suzuki HI,Young RA,Sharp PA
Thu Mar 09 00:00:00 UTC 2017
Unravelling Endogenous MicroRNA System Dysfunction as a New Pathophysiological Mechanism in Machado-Joseph Disease.
Molecular therapy : the journal of the American Society of Gene Therapy
Carmona V,Cunha-Santos J,Onofre I,Simões AT,Vijayakumar U,Davidson BL,Pereira de Almeida L
Wed Apr 05 00:00:00 UTC 2017
Unravelling Endogenous MicroRNA System Dysfunction as a New Pathophysiological Mechanism in Machado-Joseph Disease.
Molecular therapy : the journal of the American Society of Gene Therapy
Carmona V,Cunha-Santos J,Onofre I,Simões AT,Vijayakumar U,Davidson BL,Pereira de Almeida L
Wed Apr 05 00:00:00 UTC 2017
MicroRNA-independent functions of DGCR8 are essential for neocortical development and TBR1 expression.
EMBO reports
Marinaro F,Marzi MJ,Hoffmann N,Amin H,Pelizzoli R,Niola F,Nicassio F,De Pietri Tonelli D
Sat Apr 01 00:00:00 UTC 2017
MicroRNA-independent functions of DGCR8 are essential for neocortical development and TBR1 expression.
EMBO reports
Marinaro F,Marzi MJ,Hoffmann N,Amin H,Pelizzoli R,Niola F,Nicassio F,De Pietri Tonelli D
Sat Apr 01 00:00:00 UTC 2017
Noncanonical function of DGCR8 controls mESC exit from pluripotency.
The Journal of cell biology
Cirera-Salinas D,Yu J,Bodak M,Ngondo RP,Herbert KM,Ciaudo C
Wed Feb 01 00:00:00 UTC 2017
Noncanonical function of DGCR8 controls mESC exit from pluripotency.
The Journal of cell biology
Cirera-Salinas D,Yu J,Bodak M,Ngondo RP,Herbert KM,Ciaudo C
Wed Feb 01 00:00:00 UTC 2017
Canonical microRNAs Enable Differentiation, Protect Against DNA Damage, and Promote Cholesterol Biosynthesis in Neural Stem Cells.
Stem cells and development
Liu Z,Zhang C,Khodadadi-Jamayran A,Dang L,Han X,Kim K,Li H,Zhao R
Wed Feb 01 00:00:00 UTC 2017
Canonical microRNAs Enable Differentiation, Protect Against DNA Damage, and Promote Cholesterol Biosynthesis in Neural Stem Cells.
Stem cells and development
Liu Z,Zhang C,Khodadadi-Jamayran A,Dang L,Han X,Kim K,Li H,Zhao R
Wed Feb 01 00:00:00 UTC 2017
The RNA binding protein EWS is broadly involved in the regulation of pri-miRNA processing in mammalian cells.
Nucleic acids research
Ouyang H,Zhang K,Fox-Walsh K,Yang Y,Zhang C,Huang J,Li H,Zhou Y,Fu XD
Fri Dec 01 00:00:00 UTC 2017
The Fragment HMGA2-sh-3p20 from HMGA2 mRNA 3'UTR Promotes the Growth of Hepatoma Cells by Upregulating HMGA2.
Scientific reports
Wang Y,Chen F,Yang Z,Zhao M,Zhang S,Gao Y,Feng J,Yang G,Zhang W,Ye L,Zhang X
Thu May 18 00:00:00 UTC 2017
The Fragment HMGA2-sh-3p20 from HMGA2 mRNA 3'UTR Promotes the Growth of Hepatoma Cells by Upregulating HMGA2.
Scientific reports
Wang Y,Chen F,Yang Z,Zhao M,Zhang S,Gao Y,Feng J,Yang G,Zhang W,Ye L,Zhang X
Thu May 18 00:00:00 UTC 2017
Schizophrenia-Related Microdeletion Impairs Emotional Memory through MicroRNA-Dependent Disruption of Thalamic Inputs to the Amygdala.
Cell reports
Eom TY,Bayazitov IT,Anderson K,Yu J,Zakharenko SS
Tue May 23 00:00:00 UTC 2017
Schizophrenia-Related Microdeletion Impairs Emotional Memory through MicroRNA-Dependent Disruption of Thalamic Inputs to the Amygdala.
Cell reports
Eom TY,Bayazitov IT,Anderson K,Yu J,Zakharenko SS
Tue May 23 00:00:00 UTC 2017
Deficiency of DGCR8 increases bone formation through downregulation of miR-22 expression.
Bone
Choi YJ,Jeong S,Yoon KA,Sung HJ,Cho HS,Kim DW,Cho JY
Sun Oct 01 00:00:00 UTC 2017
Deficiency of DGCR8 increases bone formation through downregulation of miR-22 expression.
Bone
Choi YJ,Jeong S,Yoon KA,Sung HJ,Cho HS,Kim DW,Cho JY
Sun Oct 01 00:00:00 UTC 2017
Deficiency of DGCR8 increases bone formation through downregulation of miR-22 expression.
Bone
Choi YJ,Jeong S,Yoon KA,Sung HJ,Cho HS,Kim DW,Cho JY
Sun Oct 01 00:00:00 UTC 2017
Deficiency of DGCR8 increases bone formation through downregulation of miR-22 expression.
Bone
Choi YJ,Jeong S,Yoon KA,Sung HJ,Cho HS,Kim DW,Cho JY
Sun Oct 01 00:00:00 UTC 2017
Deficiency of DGCR8 increases bone formation through downregulation of miR-22 expression.
Bone
Choi YJ,Jeong S,Yoon KA,Sung HJ,Cho HS,Kim DW,Cho JY
Sun Oct 01 00:00:00 UTC 2017
Cytoplasmic Drosha activity generated by alternative splicing.
Nucleic acids research
Dai L,Chen K,Youngren B,Kulina J,Yang A,Guo Z,Li J,Yu P,Gu S
Thu Dec 01 00:00:00 UTC 2016
Cytoplasmic Drosha activity generated by alternative splicing.
Nucleic acids research
Dai L,Chen K,Youngren B,Kulina J,Yang A,Guo Z,Li J,Yu P,Gu S
Thu Dec 01 00:00:00 UTC 2016
Alternative splicing affects the subcellular localization of Drosha.
Nucleic acids research
Link S,Grund SE,Diederichs S
Mon Jun 20 00:00:00 UTC 2016
Alternative splicing affects the subcellular localization of Drosha.
Nucleic acids research
Link S,Grund SE,Diederichs S
Mon Jun 20 00:00:00 UTC 2016
Post-transcriptional modulation of protein phosphatase PPP2CA and tumor suppressor PTEN by endogenous siRNA cleaved from hairpin within PTEN mRNA 3'UTR in human liver cells.
Acta pharmacologica Sinica
Gao YE,Wang Y,Chen FQ,Feng JY,Yang G,Feng GX,Yang Z,Ye LH,Zhang XD
Fri Jul 01 00:00:00 UTC 2016
Post-transcriptional modulation of protein phosphatase PPP2CA and tumor suppressor PTEN by endogenous siRNA cleaved from hairpin within PTEN mRNA 3'UTR in human liver cells.
Acta pharmacologica Sinica
Gao YE,Wang Y,Chen FQ,Feng JY,Yang G,Feng GX,Yang Z,Ye LH,Zhang XD
Fri Jul 01 00:00:00 UTC 2016
The TLX-miR-219 cascade regulates neural stem cell proliferation in neurodevelopment and schizophrenia iPSC model.
Nature communications
Murai K,Sun G,Ye P,Tian E,Yang S,Cui Q,Sun G,Trinh D,Sun O,Hong T,Wen Z,Kalkum M,Riggs AD,Song H,Ming GL,Shi Y
Fri Mar 11 00:00:00 UTC 2016
The TLX-miR-219 cascade regulates neural stem cell proliferation in neurodevelopment and schizophrenia iPSC model.
Nature communications
Murai K,Sun G,Ye P,Tian E,Yang S,Cui Q,Sun G,Trinh D,Sun O,Hong T,Wen Z,Kalkum M,Riggs AD,Song H,Ming GL,Shi Y
Fri Mar 11 00:00:00 UTC 2016
MicroRNA-27b up-regulated by human papillomavirus 16 E7 promotes proliferation and suppresses apoptosis by targeting polo-like kinase2 in cervical cancer.
Oncotarget
Liu F,Zhang S,Zhao Z,Mao X,Huang J,Wu Z,Zheng L,Wang Q
Tue Apr 12 00:00:00 UTC 2016
MicroRNA-27b up-regulated by human papillomavirus 16 E7 promotes proliferation and suppresses apoptosis by targeting polo-like kinase2 in cervical cancer.
Oncotarget
Liu F,Zhang S,Zhao Z,Mao X,Huang J,Wu Z,Zheng L,Wang Q
Tue Apr 12 00:00:00 UTC 2016
Deficiency in DGCR8-dependent canonical microRNAs causes infertility due to multiple abnormalities during uterine development in mice.
Scientific reports
Kim YS,Kim HR,Kim H,Yang SC,Park M,Yoon JA,Lim HJ,Hong SH,DeMayo FJ,Lydon JP,Choi Y,Lee DR,Song H
Tue Feb 02 00:00:00 UTC 2016
Deficiency in DGCR8-dependent canonical microRNAs causes infertility due to multiple abnormalities during uterine development in mice.
Scientific reports
Kim YS,Kim HR,Kim H,Yang SC,Park M,Yoon JA,Lim HJ,Hong SH,DeMayo FJ,Lydon JP,Choi Y,Lee DR,Song H
Tue Feb 02 00:00:00 UTC 2016
Regulation of HBEGF by Micro-RNA for Survival of Developing Human Trophoblast Cells.
PloS one
Jain CV,Jessmon P,Kilburn BA,Jodar M,Sendler E,Krawetz SA,Armant DR
Mon Jun 19 00:00:00 UTC 2017
Regulation of HBEGF by Micro-RNA for Survival of Developing Human Trophoblast Cells.
PloS one
Jain CV,Jessmon P,Kilburn BA,Jodar M,Sendler E,Krawetz SA,Armant DR
Mon Jun 19 00:00:00 UTC 2017
SUMOylation at K707 of DGCR8 controls direct function of primary microRNA.
Nucleic acids research
Zhu C,Chen C,Huang J,Zhang H,Zhao X,Deng R,Dou J,Jin H,Chen R,Xu M,Chen Q,Wang Y,Yu J
Fri Sep 18 00:00:00 UTC 2015
SUMOylation at K707 of DGCR8 controls direct function of primary microRNA.
Nucleic acids research
Zhu C,Chen C,Huang J,Zhang H,Zhao X,Deng R,Dou J,Jin H,Chen R,Xu M,Chen Q,Wang Y,Yu J
Fri Sep 18 00:00:00 UTC 2015
SUMOylation at K707 of DGCR8 controls direct function of primary microRNA.
Nucleic acids research
Zhu C,Chen C,Huang J,Zhang H,Zhao X,Deng R,Dou J,Jin H,Chen R,Xu M,Chen Q,Wang Y,Yu J
Fri Sep 18 00:00:00 UTC 2015
Microprocessor mediates transcriptional termination of long noncoding RNA transcripts hosting microRNAs.
Nature structural & molecular biology
Dhir A,Dhir S,Proudfoot NJ,Jopling CL
Wed Apr 01 00:00:00 UTC 2015
DGCR8 is essential for tumor progression following PTEN loss in the prostate.
EMBO reports
Belair CD,Paikari A,Moltzahn F,Shenoy A,Yau C,Dall'Era M,Simko J,Benz C,Blelloch R
Tue Sep 01 00:00:00 UTC 2015
DGCR8 is essential for tumor progression following PTEN loss in the prostate.
EMBO reports
Belair CD,Paikari A,Moltzahn F,Shenoy A,Yau C,Dall'Era M,Simko J,Benz C,Blelloch R
Tue Sep 01 00:00:00 UTC 2015
The BDNF Val66Met variant affects gene expression through miR-146b.
Neurobiology of disease
Hsu PK,Xu B,Mukai J,Karayiorgou M,Gogos JA
Fri May 01 00:00:00 UTC 2015
The BDNF Val66Met variant affects gene expression through miR-146b.
Neurobiology of disease
Hsu PK,Xu B,Mukai J,Karayiorgou M,Gogos JA
Fri May 01 00:00:00 UTC 2015
Regulation of MicroRNA 183 by Cyclooxygenase 2 in Liver Is DEAD-Box Helicase p68 (DDX5) Dependent: Role in Insulin Signaling.
Molecular and cellular biology
Motiño O,Francés DE,Mayoral R,Castro-Sánchez L,Fernández-Velasco M,Boscá L,García-Monzón C,Brea R,Casado M,Agra N,Martín-Sanz P
Wed Jul 01 00:00:00 UTC 2015
Regulation of MicroRNA 183 by Cyclooxygenase 2 in Liver Is DEAD-Box Helicase p68 (DDX5) Dependent: Role in Insulin Signaling.
Molecular and cellular biology
Motiño O,Francés DE,Mayoral R,Castro-Sánchez L,Fernández-Velasco M,Boscá L,García-Monzón C,Brea R,Casado M,Agra N,Martín-Sanz P
Wed Jul 01 00:00:00 UTC 2015
miR-199a Links MeCP2 with mTOR Signaling and Its Dysregulation Leads to Rett Syndrome Phenotypes.
Cell reports
Tsujimura K,Irie K,Nakashima H,Egashira Y,Fukao Y,Fujiwara M,Itoh M,Uesaka M,Imamura T,Nakahata Y,Yamashita Y,Abe T,Takamori S,Nakashima K
Tue Sep 22 00:00:00 UTC 2015
miR-199a Links MeCP2 with mTOR Signaling and Its Dysregulation Leads to Rett Syndrome Phenotypes.
Cell reports
Tsujimura K,Irie K,Nakashima H,Egashira Y,Fukao Y,Fujiwara M,Itoh M,Uesaka M,Imamura T,Nakahata Y,Yamashita Y,Abe T,Takamori S,Nakashima K
Tue Sep 22 00:00:00 UTC 2015
Canonical MicroRNA Activity Facilitates but May Be Dispensable for Transcription Factor-Mediated Reprogramming.
Stem cell reports
Liu Z,Skamagki M,Kim K,Zhao R
Tue Dec 08 00:00:00 UTC 2015
Canonical MicroRNA Activity Facilitates but May Be Dispensable for Transcription Factor-Mediated Reprogramming.
Stem cell reports
Liu Z,Skamagki M,Kim K,Zhao R
Tue Dec 08 00:00:00 UTC 2015
Hippo signaling regulates microprocessor and links cell-density-dependent miRNA biogenesis to cancer.
Cell
Mori M,Triboulet R,Mohseni M,Schlegelmilch K,Shrestha K,Camargo FD,Gregory RI
Thu Feb 27 00:00:00 UTC 2014
Hippo signaling regulates microprocessor and links cell-density-dependent miRNA biogenesis to cancer.
Cell
Mori M,Triboulet R,Mohseni M,Schlegelmilch K,Shrestha K,Camargo FD,Gregory RI
Thu Feb 27 00:00:00 UTC 2014
Interplay between pre-mRNA splicing and microRNA biogenesis within the supraspliceosome.
Nucleic acids research
Agranat-Tamir L,Shomron N,Sperling J,Sperling R
Tue Apr 01 00:00:00 UTC 2014
Interplay between pre-mRNA splicing and microRNA biogenesis within the supraspliceosome.
Nucleic acids research
Agranat-Tamir L,Shomron N,Sperling J,Sperling R
Tue Apr 01 00:00:00 UTC 2014
Decreased DGCR8 expression and miRNA dysregulation in individuals with 22q11.2 deletion syndrome.
PloS one
Sellier C,Hwang VJ,Dandekar R,Durbin-Johnson B,Charlet-Berguerand N,Ander BP,Sharp FR,Angkustsiri K,Simon TJ,Tassone F
Thu Apr 23 00:00:00 UTC 2015
Decreased DGCR8 expression and miRNA dysregulation in individuals with 22q11.2 deletion syndrome.
PloS one
Sellier C,Hwang VJ,Dandekar R,Durbin-Johnson B,Charlet-Berguerand N,Ander BP,Sharp FR,Angkustsiri K,Simon TJ,Tassone F
Thu Apr 23 00:00:00 UTC 2015
DGCR8-mediated disruption of miRNA biogenesis induces cellular senescence in primary fibroblasts.
Aging cell
Gómez-Cabello D,Adrados I,Gamarra D,Kobayashi H,Takatsu Y,Takatsu K,Gil J,Palmero I
Tue Oct 01 00:00:00 UTC 2013
DGCR8-mediated disruption of miRNA biogenesis induces cellular senescence in primary fibroblasts.
Aging cell
Gómez-Cabello D,Adrados I,Gamarra D,Kobayashi H,Takatsu Y,Takatsu K,Gil J,Palmero I
Tue Oct 01 00:00:00 UTC 2013
Reduced adult hippocampal neurogenesis and working memory deficits in the Dgcr8-deficient mouse model of 22q11.2 deletion-associated schizophrenia can be rescued by IGF2.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Ouchi Y,Banno Y,Shimizu Y,Ando S,Hasegawa H,Adachi K,Iwamoto T
Wed May 29 00:00:00 UTC 2013
Reduced adult hippocampal neurogenesis and working memory deficits in the Dgcr8-deficient mouse model of 22q11.2 deletion-associated schizophrenia can be rescued by IGF2.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Ouchi Y,Banno Y,Shimizu Y,Ando S,Hasegawa H,Adachi K,Iwamoto T
Wed May 29 00:00:00 UTC 2013
Reduced adult hippocampal neurogenesis and working memory deficits in the Dgcr8-deficient mouse model of 22q11.2 deletion-associated schizophrenia can be rescued by IGF2.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Ouchi Y,Banno Y,Shimizu Y,Ando S,Hasegawa H,Adachi K,Iwamoto T
Wed May 29 00:00:00 UTC 2013
Reduced adult hippocampal neurogenesis and working memory deficits in the Dgcr8-deficient mouse model of 22q11.2 deletion-associated schizophrenia can be rescued by IGF2.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Ouchi Y,Banno Y,Shimizu Y,Ando S,Hasegawa H,Adachi K,Iwamoto T
Wed May 29 00:00:00 UTC 2013
Cyclin D1 induction of Dicer governs microRNA processing and expression in breast cancer.
Nature communications
Yu Z,Wang L,Wang C,Ju X,Wang M,Chen K,Loro E,Li Z,Zhang Y,Wu K,Casimiro MC,Gormley M,Ertel A,Fortina P,Chen Y,Tozeren A,Liu Z,Pestell RG
Tue Jul 15 00:00:00 UTC 2014
Cyclin D1 induction of Dicer governs microRNA processing and expression in breast cancer.
Nature communications
Yu Z,Wang L,Wang C,Ju X,Wang M,Chen K,Loro E,Li Z,Zhang Y,Wu K,Casimiro MC,Gormley M,Ertel A,Fortina P,Chen Y,Tozeren A,Liu Z,Pestell RG
Tue Jul 15 00:00:00 UTC 2014
Sequestration of DROSHA and DGCR8 by expanded CGG RNA repeats alters microRNA processing in fragile X-associated tremor/ataxia syndrome.
Cell reports
Sellier C,Freyermuth F,Tabet R,Tran T,He F,Ruffenach F,Alunni V,Moine H,Thibault C,Page A,Tassone F,Willemsen R,Disney MD,Hagerman PJ,Todd PK,Charlet-Berguerand N
Thu Mar 28 00:00:00 UTC 2013
Sequestration of DROSHA and DGCR8 by expanded CGG RNA repeats alters microRNA processing in fragile X-associated tremor/ataxia syndrome.
Cell reports
Sellier C,Freyermuth F,Tabet R,Tran T,He F,Ruffenach F,Alunni V,Moine H,Thibault C,Page A,Tassone F,Willemsen R,Disney MD,Hagerman PJ,Todd PK,Charlet-Berguerand N
Thu Mar 28 00:00:00 UTC 2013
Acetylation of drosha on the N-terminus inhibits its degradation by ubiquitination.
PloS one
Tang X,Wen S,Zheng D,Tucker L,Cao L,Pantazatos D,Moss SF,Ramratnam B
Wed Apr 16 00:00:00 UTC 2014
Acetylation of drosha on the N-terminus inhibits its degradation by ubiquitination.
PloS one
Tang X,Wen S,Zheng D,Tucker L,Cao L,Pantazatos D,Moss SF,Ramratnam B
Wed Apr 16 00:00:00 UTC 2014
Modulation of microRNA processing by mismatch repair protein MutLα.
Cell research
Mao G,Lee S,Ortega J,Gu L,Li GM
Fri Jun 01 00:00:00 UTC 2012
Modulation of microRNA processing by mismatch repair protein MutLα.
Cell research
Mao G,Lee S,Ortega J,Gu L,Li GM
Fri Jun 01 00:00:00 UTC 2012
Efficiency and specificity in microRNA biogenesis.
Nature structural & molecular biology
Barad O,Mann M,Chapnik E,Shenoy A,Blelloch R,Barkai N,Hornstein E
Sun May 13 00:00:00 UTC 2012
Efficiency and specificity in microRNA biogenesis.
Nature structural & molecular biology
Barad O,Mann M,Chapnik E,Shenoy A,Blelloch R,Barkai N,Hornstein E
Sun May 13 00:00:00 UTC 2012
Efficiency and specificity in microRNA biogenesis.
Nature structural & molecular biology
Barad O,Mann M,Chapnik E,Shenoy A,Blelloch R,Barkai N,Hornstein E
Sun May 13 00:00:00 UTC 2012
TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes.
Proceedings of the National Academy of Sciences of the United States of America
Kawahara Y,Mieda-Sato A
Tue Feb 28 00:00:00 UTC 2012
TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes.
Proceedings of the National Academy of Sciences of the United States of America
Kawahara Y,Mieda-Sato A
Tue Feb 28 00:00:00 UTC 2012
Histone deacetylase 1 enhances microRNA processing via deacetylation of DGCR8.
EMBO reports
Wada T,Kikuchi J,Furukawa Y
Wed Feb 01 00:00:00 UTC 2012
Histone deacetylase 1 enhances microRNA processing via deacetylation of DGCR8.
EMBO reports
Wada T,Kikuchi J,Furukawa Y
Wed Feb 01 00:00:00 UTC 2012
Histone deacetylase 1 enhances microRNA processing via deacetylation of DGCR8.
EMBO reports
Wada T,Kikuchi J,Furukawa Y
Wed Feb 01 00:00:00 UTC 2012
Histone deacetylase 1 enhances microRNA processing via deacetylation of DGCR8.
EMBO reports
Wada T,Kikuchi J,Furukawa Y
Wed Feb 01 00:00:00 UTC 2012
Dgcr8 controls neural crest cells survival in cardiovascular development.
Developmental biology
Chapnik E,Sasson V,Blelloch R,Hornstein E
Wed Feb 01 00:00:00 UTC 2012
Dgcr8 controls neural crest cells survival in cardiovascular development.
Developmental biology
Chapnik E,Sasson V,Blelloch R,Hornstein E
Wed Feb 01 00:00:00 UTC 2012
Rare Drosha splice variants are deficient in microRNA processing but do not affect general microRNA expression in cancer cells.
Neoplasia (New York, N.Y.)
Grund SE,Polycarpou-Schwarz M,Luo C,Eichmüller SB,Diederichs S
Thu Mar 01 00:00:00 UTC 2012
Rare Drosha splice variants are deficient in microRNA processing but do not affect general microRNA expression in cancer cells.
Neoplasia (New York, N.Y.)
Grund SE,Polycarpou-Schwarz M,Luo C,Eichmüller SB,Diederichs S
Thu Mar 01 00:00:00 UTC 2012
Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms.
Cell
Piskounova E,Polytarchou C,Thornton JE,LaPierre RJ,Pothoulakis C,Hagan JP,Iliopoulos D,Gregory RI
Wed Nov 23 00:00:00 UTC 2011
Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms.
Cell
Piskounova E,Polytarchou C,Thornton JE,LaPierre RJ,Pothoulakis C,Hagan JP,Iliopoulos D,Gregory RI
Wed Nov 23 00:00:00 UTC 2011
A primate herpesvirus uses the integrator complex to generate viral microRNAs.
Molecular cell
Cazalla D,Xie M,Steitz JA
Fri Sep 16 00:00:00 UTC 2011
A primate herpesvirus uses the integrator complex to generate viral microRNAs.
Molecular cell
Cazalla D,Xie M,Steitz JA
Fri Sep 16 00:00:00 UTC 2011
MCPIP1 ribonuclease antagonizes dicer and terminates microRNA biogenesis through precursor microRNA degradation.
Molecular cell
Suzuki HI,Arase M,Matsuyama H,Choi YL,Ueno T,Mano H,Sugimoto K,Miyazono K
Fri Nov 04 00:00:00 UTC 2011
MCPIP1 ribonuclease antagonizes dicer and terminates microRNA biogenesis through precursor microRNA degradation.
Molecular cell
Suzuki HI,Arase M,Matsuyama H,Choi YL,Ueno T,Mano H,Sugimoto K,Miyazono K
Fri Nov 04 00:00:00 UTC 2011
Impaired MicroRNA Processing Facilitates Breast Cancer Cell Invasion by Upregulating Urokinase-Type Plasminogen Activator Expression.
Genes & cancer
Noh H,Hong S,Dong Z,Pan ZK,Jing Q,Huang S
Tue Feb 01 00:00:00 UTC 2011
Impaired MicroRNA Processing Facilitates Breast Cancer Cell Invasion by Upregulating Urokinase-Type Plasminogen Activator Expression.
Genes & cancer
Noh H,Hong S,Dong Z,Pan ZK,Jing Q,Huang S
Tue Feb 01 00:00:00 UTC 2011
Testis-specific miRNA-469 up-regulated in gonadotropin-regulated testicular RNA helicase (GRTH/DDX25)-null mice silences transition protein 2 and protamine 2 messages at sites within coding region: implications of its role in germ cell development.
The Journal of biological chemistry
Dai L,Tsai-Morris CH,Sato H,Villar J,Kang JH,Zhang J,Dufau ML
Fri Dec 30 00:00:00 UTC 2011
Testis-specific miRNA-469 up-regulated in gonadotropin-regulated testicular RNA helicase (GRTH/DDX25)-null mice silences transition protein 2 and protamine 2 messages at sites within coding region: implications of its role in germ cell development.
The Journal of biological chemistry
Dai L,Tsai-Morris CH,Sato H,Villar J,Kang JH,Zhang J,Dufau ML
Fri Dec 30 00:00:00 UTC 2011
Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha.
Molecular cell
Davis BN,Hilyard AC,Nguyen PH,Lagna G,Hata A
Fri Aug 13 00:00:00 UTC 2010
Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha.
Molecular cell
Davis BN,Hilyard AC,Nguyen PH,Lagna G,Hata A
Fri Aug 13 00:00:00 UTC 2010
Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha.
Molecular cell
Davis BN,Hilyard AC,Nguyen PH,Lagna G,Hata A
Fri Aug 13 00:00:00 UTC 2010
Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha.
Molecular cell
Davis BN,Hilyard AC,Nguyen PH,Lagna G,Hata A
Fri Aug 13 00:00:00 UTC 2010
MicroRNAs control hepatocyte proliferation during liver regeneration.
Hepatology (Baltimore, Md.)
Song G,Sharma AD,Roll GR,Ng R,Lee AY,Blelloch RH,Frandsen NM,Willenbring H
Sat May 01 00:00:00 UTC 2010
MicroRNAs control hepatocyte proliferation during liver regeneration.
Hepatology (Baltimore, Md.)
Song G,Sharma AD,Roll GR,Ng R,Lee AY,Blelloch RH,Frandsen NM,Willenbring H
Sat May 01 00:00:00 UTC 2010
Regulation of the microRNA processor DGCR8 by the tumor suppressor ING1.
Cancer research
Gómez-Cabello D,Callejas S,Benguría A,Moreno A,Alonso J,Palmero I
Mon Mar 01 00:00:00 UTC 2010
Regulation of the microRNA processor DGCR8 by the tumor suppressor ING1.
Cancer research
Gómez-Cabello D,Callejas S,Benguría A,Moreno A,Alonso J,Palmero I
Mon Mar 01 00:00:00 UTC 2010
Regulation of the microRNA processor DGCR8 by the tumor suppressor ING1.
Cancer research
Gómez-Cabello D,Callejas S,Benguría A,Moreno A,Alonso J,Palmero I
Mon Mar 01 00:00:00 UTC 2010
Regulation of the microRNA processor DGCR8 by the tumor suppressor ING1.
Cancer research
Gómez-Cabello D,Callejas S,Benguría A,Moreno A,Alonso J,Palmero I
Mon Mar 01 00:00:00 UTC 2010
miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues.
Aging
Saunders LR,Sharma AD,Tawney J,Nakagawa M,Okita K,Yamanaka S,Willenbring H,Verdin E
Thu Jul 01 00:00:00 UTC 2010
miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues.
Aging
Saunders LR,Sharma AD,Tawney J,Nakagawa M,Okita K,Yamanaka S,Willenbring H,Verdin E
Thu Jul 01 00:00:00 UTC 2010
Modulation of microRNA processing by p53.
Nature
Suzuki HI,Yamagata K,Sugimoto K,Iwamoto T,Kato S,Miyazono K
Thu Jul 23 00:00:00 UTC 2009
Modulation of microRNA processing by p53.
Nature
Suzuki HI,Yamagata K,Sugimoto K,Iwamoto T,Kato S,Miyazono K
Thu Jul 23 00:00:00 UTC 2009
Existence of a microRNA pathway in anucleate platelets.
Nature structural & molecular biology
Landry P,Plante I,Ouellet DL,Perron MP,Rousseau G,Provost P
Tue Sep 01 00:00:00 UTC 2009
Existence of a microRNA pathway in anucleate platelets.
Nature structural & molecular biology
Landry P,Plante I,Ouellet DL,Perron MP,Rousseau G,Provost P
Tue Sep 01 00:00:00 UTC 2009
Existence of a microRNA pathway in anucleate platelets.
Nature structural & molecular biology
Landry P,Plante I,Ouellet DL,Perron MP,Rousseau G,Provost P
Tue Sep 01 00:00:00 UTC 2009
Existence of a microRNA pathway in anucleate platelets.
Nature structural & molecular biology
Landry P,Plante I,Ouellet DL,Perron MP,Rousseau G,Provost P
Tue Sep 01 00:00:00 UTC 2009
Cell-cell contact globally activates microRNA biogenesis.
Proceedings of the National Academy of Sciences of the United States of America
Hwang HW,Wentzel EA,Mendell JT
Tue Apr 28 00:00:00 UTC 2009
Cell-cell contact globally activates microRNA biogenesis.
Proceedings of the National Academy of Sciences of the United States of America
Hwang HW,Wentzel EA,Mendell JT
Tue Apr 28 00:00:00 UTC 2009
Post-transcriptional control of DGCR8 expression by the Microprocessor.
RNA (New York, N.Y.)
Triboulet R,Chang HM,Lapierre RJ,Gregory RI
Mon Jun 01 00:00:00 UTC 2009
Post-transcriptional control of DGCR8 expression by the Microprocessor.
RNA (New York, N.Y.)
Triboulet R,Chang HM,Lapierre RJ,Gregory RI
Mon Jun 01 00:00:00 UTC 2009
The NF90-NF45 complex functions as a negative regulator in the microRNA processing pathway.
Molecular and cellular biology
Sakamoto S,Aoki K,Higuchi T,Todaka H,Morisawa K,Tamaki N,Hatano E,Fukushima A,Taniguchi T,Agata Y
Wed Jul 01 00:00:00 UTC 2009
The NF90-NF45 complex functions as a negative regulator in the microRNA processing pathway.
Molecular and cellular biology
Sakamoto S,Aoki K,Higuchi T,Todaka H,Morisawa K,Tamaki N,Hatano E,Fukushima A,Taniguchi T,Agata Y
Wed Jul 01 00:00:00 UTC 2009
Suppression of HIV-1 replication by microRNA effectors.
Retrovirology
Chable-Bessia C,Meziane O,Latreille D,Triboulet R,Zamborlini A,Wagschal A,Jacquet JM,Reynes J,Levy Y,Saib A,Bennasser Y,Benkirane M
Mon Mar 09 00:00:00 UTC 2009
Suppression of HIV-1 replication by microRNA effectors.
Retrovirology
Chable-Bessia C,Meziane O,Latreille D,Triboulet R,Zamborlini A,Wagschal A,Jacquet JM,Reynes J,Levy Y,Saib A,Bennasser Y,Benkirane M
Mon Mar 09 00:00:00 UTC 2009
Primary microRNA transcripts are processed co-transcriptionally.
Nature structural & molecular biology
Morlando M,Ballarino M,Gromak N,Pagano F,Bozzoni I,Proudfoot NJ
Mon Sep 01 00:00:00 UTC 2008
Primary microRNA transcripts are processed co-transcriptionally.
Nature structural & molecular biology
Morlando M,Ballarino M,Gromak N,Pagano F,Bozzoni I,Proudfoot NJ
Mon Sep 01 00:00:00 UTC 2008
