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Product Details
PA5-101997
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human DGKB(Accession Q9Y6T7), corresponding to amino acid residues L656-A706.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2851429
Product Specific Information
Antibody detects endogenous levels of total DGKB.
Target Information
Diacylglycerol (DAG) is an allosteric activator of protein kinase C. DAG also participates in regulating RAS and RHO family proteins by activating the guanine nucleotide exchange factors VAV and RASGRP1. DAG is also involved in the synthesis of phospholipids and triacylglycerols. Tight regulation of DAG levels is achieved via DAG kinases (DGKs), which remove DAG by phosphorylate it to phosphatidic acid. Several mammalian isozymes of DAGK have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 90 kDa diacylglycerol kinase; DAG kinase beta; DGK-beta; Diacylglycerol kinase 90kDa; Diacylglycerol kinase beta; diacylglycerol kinase beta, 90kDa; diacylglycerol kinase, beta 90kDa; Diglyceride kinase beta
Gene Aliases: 6430574F24; 90kda; C630029D13Rik; Dagk; DAGK2; DGK; DGK-BETA; DGKB; KIAA0718; mKIAA0718
UniProt ID: (Human) Q9Y6T7, (Rat) P49621, (Mouse) Q6NS52
Entrez Gene ID: (Human) 1607, (Rat) 54248, (Mouse) 217480
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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