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Invitrogen
DGKZ Polyclonal Antibody
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Product Details
PA5-50613
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues near the C terminal of human diacylglycerol kinase, zeta
Conjugate
Form
Liquid
Concentration
2.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2636066
Product Specific Information
The antibody detects endogenous levels of total DGKZ protein.
Target Information
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 104 kDa diacylglycerol kinase; DAG kinase DAGK6; DAG kinase zeta; DGK-IV; DGK-zeta; Diacylglycerol kinase zeta; diacylglycerol kinase, zeta 104kDa; Diglyceride kinase; Diglyceride kinase zeta
Gene Aliases: DAGK5; DAGK6; DGK-ZETA; DGKZ; E130307B02Rik; ENSMUSG00000075035; F730209L11Rik; hDGKzeta; mDGK[z]
UniProt ID: (Human) Q13574, (Mouse) Q80UP3, (Rat) O08560
Entrez Gene ID: (Human) 8525, (Mouse) 104418, (Rat) 81821
protein kinase C-activating G-protein coupled receptor signaling pathway
phosphorylation
mitotic G1 DNA damage checkpoint
intracellular signal transduction
negative regulation of catalytic activity
negative regulation of mitotic cell cycle
negative regulation of Ras protein signal transduction
lipid phosphorylation
cell migration
platelet activation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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