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Product Details
11021-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DHX16 Fusion Protein Ag1482 (1-310 aa encoded by BC009392)
Conjugate
Form
Liquid
Concentration
0.35 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MATPAGLER WVQDELHSVL GLSERHVAQF LIGTAQRCTS AEEFVQRLRD TDTLDLSGPA RDFALRLWNK VPRKAVVEKP ARAAEREARA LLEKNRSYRL LEDSEESSEE TVSRAGSSLQ KKRKKRKHLR KKREEEEEEE ASEKGKKKTG GSKQQTEKPE SEDEWERTER ERLQDLEERD AFAERVRQRD KDRTRNVLER SDKKAYEEAQ KRLKMAEEDR KAMVPELRKK SRREYLAKRE REKLEDLEAE LADEEFLFGD VELSRHERQE LKYKRRVRDL AREYRAAGEQ EKLEATNRYH MPKETRGQPA R (1-310 aa encoded by BC009392)
Target Information
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a functional homolog of fission yeast Prp8 protein involved in cell cycle progression. This gene is mapped to the MHC region on chromosome 6p21.3, a region where many malignant, genetic and autoimmune disease genes are linked. Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP-dependent RNA helicase #3; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 16; DEAD/H box 16; DEAH (Asp-Glu-Ala-His) box polypeptide 16; DEAH-box protein 16; Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; RNA helicase
Gene Aliases: 2410006N22Rik; DBP2; DDX16; DHX16; KIAA0577; mKIAA0577; PRO2014; PRP2; PRP8; PRPF2
UniProt ID: (Human) O60231
Entrez Gene ID: (Human) 8449, (Mouse) 69192
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