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Proteintech
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Immunogen sequence: CNLGSPEDF LSKALDPPQL QVISNAMNLL RKIGACELNE PKLTPLGQHL AALPVNVKIG KMLIFGAIFG CLDPVATLAA VMTEKSPFTT PIGRKDEADL AKSALAMADS DHLTIYNAYL GWKKARQEGG YRSEITYCRR NFLNRTSLLT LEDVKQELIK LVKAAGFSSS TTSTSWEGNR ASQTLSFQEI ALLKAVLVAG LYDNVGKIIY TKSVDVTEKL ACIVETAQGK AQVHPSSVNR DLQTHGWLLY QEKIRYARVY LRETTLITPF PVLLFGGDIE VQHRERLLSI DGWIYFQAPV KIAVIFKQLR VLIDSVLRKK LENPKMSLEN DKILQIITEL IKTENN (1025-1369 aa encoded by BC056219)
DNA helicase and probable main scaffold component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair; according to PubMed:20687897 the contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation. Recruited by YY1 to YY1-activated genes, where it acts as an essential coactivator. Binds DNA. In vitro, has double-stranded DNA-dependent ATPase activity. Involved in UV-damage excision repair, DNA replication and chromosome segregation during normal cell division cycle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATP-dependent RNA helicase DHX29; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 29; DEAH (Asp-Glu-Ala-His) box polypeptide 29; DEAH box protein 29; Nucleic acid helicase DDXx
Gene Aliases: 3732415M03; AU043276; DDX29; Ddxx; DHX29; E130202M19Rik
UniProt ID: (Human) Q7Z478, (Mouse) Q6PGC1
Entrez Gene ID: (Human) 54505, (Mouse) 218629, (Rat) 100362324
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