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Proteintech
DIXDC1 Polyclonal Antibody
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Product Details
13816-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DIXDC1 Fusion Protein Ag4904 (330-683 aa encoded by BC033034)
Conjugate
Form
Liquid
Concentration
0.27 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: VNPEEQLII IQSRLDQSME ENQDLKKELL KCKQEARNLQ GIKDALQQRL TQQDTSVLQL KQELLRANMD KDELHNQNVD LQRKLDERNR LLGEYKKELG QKDRLLQQHQ AKLEEALRKL SDVSYHQVDL ERELEHKDVL LAHCMKREAD EATNYNSHNS QSNGFLLPTA GKGATSVSNR GTSDLQLVRD ALRSLRNSFS GHDPQHHTID SLEQGISSLM ERLHVMETQK KQERKVRVKS PRTQVGSEYR ESWPPNSKLP HSQSSPTVSS TCTKVLYFTD RSLTPFMVNI PKRLEEVTLK DFKAAIDREG NHRYHFKALD PEFGTVKEEI FHDDDAIPGW EGKIVAWVEE DHGEN (330-683 aa encoded by BC033034)
Target Information
This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Coiled-coil protein DIX1; Coiled-coil-DIX1; DIX domain-containing protein 1; Dixin
Gene Aliases: 4930563F16Rik; BC048182; CCD1; Ccd1Aalpha1L; Ccd1Abeta1L; Ccd1BalphaL; Ccd1BbetaL; Ccd1CL; DIXDC1; KIAA1735; mKIAA1735
UniProt ID: (Human) Q155Q3, (Mouse) Q80Y83
Entrez Gene ID: (Human) 85458, (Mouse) 330938, (Rat) 363062
cell cycle
multicellular organism development
Wnt signaling pathway
cerebellar cortex development
cerebral cortex cell migration
cerebral cortex radially oriented cell migration
cell proliferation in forebrain
forebrain ventricular zone progenitor cell division
positive regulation of Wnt signaling pathway
regulation of actin cytoskeleton organization
negative regulation of neuron differentiation
regulation of JNK cascade
positive regulation of JNK cascade
positive regulation of axonogenesis
canonical Wnt signaling pathway
regulation of microtubule cytoskeleton organization
positive regulation of canonical Wnt signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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