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Abnova
DIXDC1 Polyclonal Antibody, MaxPab™
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Product Details
H00085458-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DIXDC1 (NP_219493.1, 1 a.a. approximately 472 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MGGTQVKCLT SPSPIHSAKS ESIITQSEEK ADFVIIPAEG IENRTEGTDS PLSRDWRPGS PGTYLETSWE EQLLEQQEYL EKEMEEAKKM ISGLQALLLN GSLPEDEQER PLALCEPGVN PEEQLIIIQS RLDQSMEENQ DLKKELLKCK QEARNLQGIK DALQQRLTQQ DTSVLQLKQE LLRANMDKDE LHNQNVDLQR KLDERNRLLG EYKKELGQKD RLLQQHQAKL EEALRKLSDV SYHQVDLERE LEHKDVLLAH CMKREADEAT NYNSHNSQSN GFLLPTAGKG ATSVSNRGTS DLQLVRDALR SLRNSFSGHD PQHHTIDSLE QGISSLMERL HVMETQKKQE RKVRVKSPRT QVGSEYRESW PPNSKLPHSQ SSPTVSSTCT KVLYFTDRSL TPFMVNIPKR LEEVTLKDFK AAIDREGNHR YHFKALDPEF GTVKEEIFHD DDAIPGWEGK IVAWVEEDHG EN
Target Information
This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Coiled-coil protein DIX1; Coiled-coil-DIX1; DIX domain-containing protein 1; Dixin
Gene Aliases: CCD1; DIXDC1; KIAA1735
UniProt ID: (Human) Q155Q3
Entrez Gene ID: (Human) 85458
cell cycle
cerebral cortex radially oriented cell migration
forebrain ventricular zone progenitor cell division
regulation of actin cytoskeleton organization
negative regulation of neuron differentiation
canonical Wnt signaling pathway
regulation of microtubule cytoskeleton organization
positive regulation of canonical Wnt signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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