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Invitrogen
DLL1 Polyclonal Antibody
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DLL1 Antibody (PA5-47556) in IHC (F)
Immunohistochemical analysis of DLL1 in immersion fixed frozen sections of embryonic mouse stomach (E13.5). Samples were incubated in DLL1 polyclonal antibody (Product # PA5-47556) using a dilution of 10 µg/mL overnight at 4 °C followed by NorthernLights™ 557-conjugated Anti-Sheep IgG Secondary Antibody (red) and counterstained with DAPI (blue).
Product Details
PA5-47556
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Sheep
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant rat DLL1 Gln18-Trp537 (predicted)
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2607385
Product Specific Information
In direct ELISAs, approximately 10% cross-reactivity with recombinant human DLL-1 is observed and less than 1% cross-reactivity with recombinant rat Notch-1 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Delta-like protein 1 (DLL1) is a transmembrane protein characterized by epidermal growth factor (EGF)-like repeats. It is a ligand for Notch receptor. It blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: delta like-1; Delta-like protein 1; Delta1; Drosophila Delta homolog 1; OTTHUMP00000017690
Gene Aliases: Delta1; Dll1
UniProt ID: (Mouse) Q61483, (Rat) P97677
Entrez Gene ID: (Mouse) 13388, (Rat) 84010
in utero embryonic development
somitogenesis
somite specification
heart looping
cell communication
Notch signaling pathway
cell-cell signaling
multicellular organism development
determination of left/right symmetry
compartment pattern specification
nervous system development
organ morphogenesis
auditory receptor cell fate commitment
cell differentiation
negative regulation of interleukin-10 production
inner ear morphogenesis
odontogenesis of dentin-containing tooth
auditory receptor cell differentiation
negative regulation of cell differentiation
negative regulation of auditory receptor cell differentiation
negative regulation of myeloid cell differentiation
negative regulation of neuron differentiation
positive regulation of Notch signaling pathway
positive regulation of transcription from RNA polymerase II promoter
inner ear development
regulation of neurogenesis
Notch signaling involved in heart development
left/right axis specification
cell fate determination
proximal tubule development
loop of Henle development
neuronal stem cell population maintenance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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