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Invitrogen
DLL1 Polyclonal Antibody
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DLL1 Antibody (PA5-85819) in WB
Western blot analysis of DLL1 in mouse tissue extract using DLL1 polyclonal antibody (Product # PA5-85819) using 50 µg of sample at a dilution of 1:100. Sample was then incubated with HRP-conjugated anti-rabbit IgG secondary antibody. Prior to incubation with primary antibody, the sample was separated on 7.5% SDS-PAGE.
Product Details
PA5-85819
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the Extracellular domain of human DLL1. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.81 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2792955
Product Specific Information
Keep as concentrated solution.
Predicted reactivity: Mouse (87%), Rat (84%), Chicken (81%).
Positive Control: mouse heart.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Delta-like protein 1 (DLL1) is a transmembrane protein characterized by epidermal growth factor (EGF)-like repeats. It is a ligand for Notch receptor. It blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: delta like-1; Delta-like protein 1; Delta1; Drosophila Delta homolog 1; H-Delta-1; OTTHUMP00000017690
Gene Aliases: Delta; DELTA1; DL1; DLL1; UNQ146/PRO172
UniProt ID: (Human) O00548, (Mouse) Q61483
Entrez Gene ID: (Human) 28514, (Mouse) 13388
in utero embryonic development
somitogenesis
somite specification
heart looping
cell communication
Notch signaling pathway
cell-cell signaling
multicellular organism development
determination of left/right symmetry
compartment pattern specification
nervous system development
organ morphogenesis
auditory receptor cell fate commitment
cell differentiation
negative regulation of interleukin-10 production
inner ear morphogenesis
odontogenesis of dentin-containing tooth
auditory receptor cell differentiation
negative regulation of cell differentiation
negative regulation of auditory receptor cell differentiation
negative regulation of myeloid cell differentiation
negative regulation of neuron differentiation
positive regulation of Notch signaling pathway
positive regulation of transcription from RNA polymerase II promoter
inner ear development
regulation of neurogenesis
Notch signaling involved in heart development
left/right axis specification
cell fate determination
marginal zone B cell differentiation
type B pancreatic cell development
Notch receptor processing
regulation of blood pressure
positive regulation of cell proliferation
negative regulation of cell proliferation
proximal/distal pattern formation
astrocyte development
regulation of somitogenesis
spinal cord development
cerebellar molecular layer formation
cerebellar Purkinje cell layer structural organization
hemopoiesis
regulation of cell adhesion
negative regulation of epithelial cell differentiation
negative regulation of glial cell apoptotic process
organ growth
regulation of growth
negative regulation of epidermal cell differentiation
negative regulation of myoblast differentiation
positive regulation of endocytosis
lateral inhibition
skeletal muscle tissue growth
regulation of skeletal muscle tissue growth
positive regulation of skeletal muscle tissue growth
neuron fate specification
regulation of cell division
retina development in camera-type eye
retina morphogenesis in camera-type eye
Notch signaling pathway involved in arterial endothelial cell fate commitment
nephron development
proximal tubule development
loop of Henle development
clathrin-mediated endocytosis
endothelial tip cell fate specification
neuronal stem cell population maintenance
skin epidermis development
regulation of vascular endothelial growth factor signaling pathway
positive regulation of sprouting angiogenesis
regulation of energy homeostasis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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