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Invitrogen
DLL3 Recombinant Human Monoclonal Antibody (7B7)
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DLL3 Antibody (MA5-43156) in Flow
Flow Cytometry analysis of DLL3 in untransfected HEK293 cells (green line) and transfected Human DLL3 HEK293 stable cells (red line) using DLL3 Monoclonal Antibody (Product # MA5-43156) (2 µL/1x10^6cells), washed and then followed by FITC-conjugated anti-Human IgG1 Fc antibody.
Product Details
MA5-43156
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Human
/ IgG1
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
7B7
Immunogen
Recombinant Human DLL3 protein
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2912292
Product Specific Information
Antibody tested in Indirect ELISA
Target Information
Delta-like protein 3 (DLL3) is a ligand for the Notch signaling pathway. It inhibits primary neurogenesis. DLL3 plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. Defects in DLL3 are the cause of Spondylocostal dysostosis autosomal recessive type 1 (SCDO1). Mutations in DLL3 gene cause truncal shortening relative to their limbs, which leads to abdominal protrusion, abnormal spinal curvature and sometimes a plagiocephaly-torticollis sequence. It may be required to divert neurons along a specific differentiation pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: delta-like 3; Delta-like protein 3; Delta3; Drosophila Delta homolog 3
Gene Aliases: DLL3; SCDO1
UniProt ID: (Human) Q9NYJ7
Entrez Gene ID: (Human) 10683
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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