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The protein encoded by this gene is a zinc finger protein that may act as a transcription factor. The encoded protein may be part of a BHC histone deacetylase complex. Translocation of this gene with the fibroblast growth factor receptor-1 gene (FGFR1) results in a fusion gene, which may be a cause of stem cell leukemia lymphoma syndrome (SCLL). Several transcript variants encoding the same protein have been found for this gene.
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Protein Aliases: DNA polymerase alpha 2, 68 kDa; DNA polymerase alpha 70 kDa subunit; DNA polymerase alpha subunit B; DNA polymerase alpha subunit II; DNA polymerase subunit II; DNA-directed DNA polymerase alpha 2; Ese1L; polymerase (DNA directed), alpha 2 (70kD subunit); polymerase (DNA directed), alpha 2, accessory subunit; polymerase (DNA) alpha 2, accessory subunit; polymerase (DNA-directed), alpha (70kD)
Gene Aliases: AI573378; POLA2
UniProt ID: (Human) Q14181, (Mouse) P33611
Entrez Gene ID: (Human) 23649, (Mouse) 18969, (Rat) 85242
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