Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
DNAI1 Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
FIGURE: 1 / 1
DNAI1 Antibody (PA5-88366) in WB
Western blot analysis of DNAI1 in extracts of various cell lines. Samples were incubated with DNAI1 Polyclonal antibody (Product # PA5-88366) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
Product Details
PA5-88366
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 350-699 of human DNAI1 (NP_0362761)
Conjugate
Form
Liquid
Concentration
0.52 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2804861
Product Specific Information
Immunogen sequence: VGYGSYDFMK QSRGMLLLYS LKNPSFPEYM FSSNSGVMCL DIHVDHPYLV AVGHYDGNVA IYNLKKPHSQ PSFCSSAKSG KHSDPVWQVK WQKDDMDQNL NFFSVSSDGR IVSWTLVKRK LVHIDVIKLK VEGSTTEVPE GLQLHPVGCG TAFDFHKEID YMFLVGTEEG KIYKCSKSYS SQFLDTYDAH NMSVDTVSWN PYHTKVFMSC SSDWTVKIWD HTIKTPMFIY DLNSAVGDVA WAPYSSTVFA AVTTDGKAHI FDLAINKYEA ICNQPVAAKK NRLTHVQFNL IHPIIIVGDD RGHIISLKLS PNLRKMPKEK KGQEVQKGPA VEIAKLDKLL NLVREVKIKT; Positive Samples: HeLa, SKOV3, U-87MG, Mouse kidney; Cellular Location: Cytoplasm, cilium axoneme, cytoskeleton
Target Information
Eukaryotic cells rely on actin and microtubule-based protein "motors" to generate intracellular movements. These protein "motors" contain specialized domains that hydrolyze ATP to produce force and movement along a cytoskeletal polymer (actin in the case of myosin family and microtubules in the case of the kinesin family and dyneins). Dynein has been implicated in cytoplasmic motile functions, including chromosomal movement, retrograde organelle and axonal transport, the endocytic pathway, and the organization of the Golgi apparatus. In all cell types, dynein has the same basic structures and is composed of two or three distinct heavy chains (~450 kDa), three intermediate chains (70-125 kDa), and at least four light chains (15-25 kDa).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Axonemal dynein intermediate chain 1; Dynein axonemal intermediate chain 1; dynein, axonemal, intermediate chain 1; dynein, axonemal, intermediate polypeptide 1; ICS; immotile cilia syndrome 1; MGC26204; RP11-296L22.2; testis tissue sperm-binding protein Li 87P
Gene Aliases: CILD1; DIC1; DNAI1; ICS1; PCD
UniProt ID: (Human) Q9UI46
Entrez Gene ID: (Human) 27019
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support