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Invitrogen
DNAI1 Polyclonal Antibody
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DNAI1 Antibody (PA5-99618) in IHC (P)
Immunohistochemistry analysis of DNAI1 in human kidney cancer and para-carcinoma tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with DNAI1 polyclonal antibody (Product # PA5-99618) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-99618
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human DNAI1(Accession Q9UI46), corresponding to amino acid residues I644-E694.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2818551
Product Specific Information
Antibody detects endogenous levels of total Dynein IC1.
Target Information
Eukaryotic cells rely on actin and microtubule-based protein "motors" to generate intracellular movements. These protein "motors" contain specialized domains that hydrolyze ATP to produce force and movement along a cytoskeletal polymer (actin in the case of myosin family and microtubules in the case of the kinesin family and dyneins). Dynein has been implicated in cytoplasmic motile functions, including chromosomal movement, retrograde organelle and axonal transport, the endocytic pathway, and the organization of the Golgi apparatus. In all cell types, dynein has the same basic structures and is composed of two or three distinct heavy chains (~450 kDa), three intermediate chains (70-125 kDa), and at least four light chains (15-25 kDa).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Axonemal dynein intermediate chain 1; Dynein axonemal intermediate chain 1; dynein, axonemal, intermediate chain 1; dynein, axonemal, intermediate polypeptide 1; ICS; immotile cilia syndrome 1; MGC26204; RP11-296L22.2; testis tissue sperm-binding protein Li 87P
Gene Aliases: CILD1; DIC1; DNAI1; ICS1; PCD
UniProt ID: (Human) Q9UI46
Entrez Gene ID: (Human) 27019
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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