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Invitrogen
DNAJB6 Monoclonal Antibody (K24018_5D5)
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DNAJB6 Antibody (MA5-55688) in IHC (P)
Immunohistochemistry analysis of DNAJB6 in paraffin-embedded testis tissue. Sample was incubated with DNAJB6 monoclonal antibody (Product # MA5-55688) at a dilution of 5 µg/mL (RT, 1 hour). Antigen was retrieved through addition of boiling Tris/EDTA buffer pH 9 in a pressure cooker for 3 min. Endogenous peroxidase activity was quenched by incubating the sections with 3% H2O2 for 30 min at room temperature. ... View More
Product Details
MA5-55688
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
K24018_5D5
Immunogen
Recombinant human DNAJB6 (immunogen range is 11-240).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
AB_3667920
Product Specific Information
Sequence of this protein is as follows: QRHASPEDIK KAYRKLALKW HPDKNPENKE EAERKFKQVA EAYEVLSDAK KRDIYDKYGK EGLNGGGGGG SHFDSPFEFG FTFRNPDDVF REFFGGRDPF SFDFFEDPFE DFFGNRRGPR GSRSRGTGSF FSAFSGFPSF GSGFSSFDTG FTSFGSLGHG GLTSFSSTSF GGSGMGNFKS ISTSTKMVNG RKITTKRIVE NGQERVEVEE DGQLKSLTIN GVADDDALAE
Target Information
This gene encodes a member of the DNAJ protein family. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. This family member may also play a role in polyglutamine aggregation in specific neurons. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been fully described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DnaJ (Hsp40) homolog, subfamily B, member 6; DnaJ homolog subfamily B member 6; DnaJ-like 2 protein; Heat shock protein J2; HHDJ1; HSJ-2; mammalian relative of DnaJ; mDj4; MRJ; MSJ-1
Gene Aliases: DJ4; DnaJ; DNAJB6; HHDJ1; HSJ-2; HSJ2; LGMD1D; LGMD1E; mDj4; MRJ; MSJ-1; MSJ1
UniProt ID: (Human) O75190, (Mouse) O54946
Entrez Gene ID: (Human) 10049, (Mouse) 23950
protein folding
actin cytoskeleton organization
extracellular matrix organization
positive regulation of ATPase activity
regulation of protein localization
protein localization to nucleus
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
intermediate filament organization
negative regulation of transcription, DNA-templated
chorio-allantoic fusion
syncytiotrophoblast cell differentiation involved in labyrinthine layer development
chorion development
negative regulation of inclusion body assembly
regulation of cellular response to heat
chaperone-mediated protein folding
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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